Irina Blumenstein

Patient Reported Outcomes (PROs) in Inflammatory Bowel Disease (IBD) around the World mdpi.com/si/205569 #mdpijcm via @JCM_MDPI Please submit your manuscript!

Merci. #NotreDameDeParis

Spatially restricted immune and microbiota-driven adaptation of the gut @NaturePortfolio #IBD pubmed.ncbi.nlm.nih.gov/39567686/ @IBD_FloMD @Y_ECCO_IBD @DignassAxel @RajaAtreya @fgomollon @bverstockt @IBD_MB @I_Blumenstein @FernandoMagro6 @alearmuzzi @IBD_JohnD @vipuljairath @RPanaccione

Gestern haben wir Abschied feiern müssen- mit einem lachenden und weinenden Auge. Liebe Andrea, alles Gute und viel Erfolg an der @UKKoeln - ich bin sicher, du wirst eine ganz tolle Direktorin und Vorbild. Wir werden dich in Frankfurt sehr vermissen. 3x W3, 3x 👩🏼, 6x 👧🏼 👦🏻

Hot off the press : the #ECCO 2024 #Guidelines on Therapeutics in #CD: Medical Treatment. Excellently lead by Hannah Gordon and @IBD_MB, in close collaboration with ECCO GuiCom, @efcca and many clinicians globally. @Y_ECCO_IBD academic.oup.com/ecco-jcc/advan…

Nature research paper: A disease-associated gene desert directs macrophage inflammation through ETS2 go.nature.com/45iCJzK

This work took 3⃣ years from conception to publication in @NatureRevGastro ‘A global consensus on definitions, diagnosis and management of fibrostenosing small bowel Crohn’s disease in clinical practice’ Essentials on this challenging #IBD treatment situation in a 🧵 1/11

#Choy: PREDICT UC: OPTIMISING INFLIXIMAB INDUCTION THERAPY FOR ACUTE SEVERE ULCERATIVE COLITIS - A RANDOMISED CONTROLLED TRIAL #DDW2024 @Y_ECCO_IBD @fgomollon @IBD_FloMD @AshkanRA @DCharabaty @I_Blumenstein @QueirozNataliaF @RestelliniS

A tremendous effort from @UmaMahadevanIBD and @MLongMD consolidating pregnancy data from around the 🌎 -rotavirus💉should be given on schedule in infants with in utero TNF -active flare=teratogen -breastfeeding safe with mAb use -preeclampsia is a major risk, start low dose asa

🚨Strategies for targeting cytokines in #IBD @NatRevImmunol Timely, comprehensive and elegant state of the art by #MarkusNeurath @Y_ECCO_IBD @IBD_FloMD @fgomollon @I_Blumenstein @DCharabaty @GianlucaPellino @bverstockt @ibddoctor @IBD_JohnD @RajaAtreya

@drRobinDud @MWiestler @IBD @JCGjournal @WorldGastroOrg @laura_targownik @MRegueiroMD @DignassAxel @LumirKunovsky @alearmuzzi @UmaMahadevanIBD @vipuljairath @ibdseb @RestelliniS @silvio_silvio75 71 patients…. Rather small study for such impactful conclusions. How was their IBD managed?

Hormonal Contraceptives in women with #IBD: ➕Reduce ⬇️ Active Symptomatic 😣 Disease #IBDSI ➖ but May ⬆️ Increase Intestinal 🔥 Inflammation #FCAL>250 ug/g 🔜 More data among👩‍🔬🧕👩‍🏫of reproductive age with @IBD are needed pubmed.ncbi.nlm.nih.gov/38349017/ @JCGjournal @WorldGastroOrg

Impressive start of #ECCO24 by #NuruNoor presenting results from #PROFILE. Paradigm-changing re the use of top-down in #IBD? 👉🏼Severe endoscopic activity -> higher response 👉🏼No pts with mild CD included 👉🏼 Biomarker neg @Y_ECCO_IBD @GianlucaPellino @IBD_FloMD @EdwardLoftus2

Data from PROFILE trial Amazing presentation by Nuru Noor Top down IFX+IMM from diagnosis of #CD shows: -⬆️sustained steroid & surgery-free remission -No increase in serious infections
-67% endoscopic remission rate and 10x ⬇️in urgent abdominal surgery #ECCO2024 #ECCO24

New 2-year postdoc position available in my lab @TheCrick to test novel therapies for #IBD and related diseases by targeting a master regulator of #macrophage-driven inflammation using antibody-drug conjugates and related tools. Apply here: crick.wd3.myworkdayjobs.com/External/job/L… Pls retweet!

Access to all abstracts of #ECCO2024 👇🏿👇🏼👇 ecco-ibd.eu/publications/c… @IBD_FloMD @alearmuzzi @FernandoMagro6 @DignassAxel @charlie_lees @DignassAxel @RPanaccione @pakotze @RestelliniS @BattatMD4IBD @IBD_JohnD @GianlucaPellino @NuhaZsurgeon @I_Blumenstein @bverstockt @Y_ECCO_IBD

@Bealoquebea @AshkanRA @DCharabaty @IBDimmunology @fgomollon @ign76 @sepdigestiva That is brilliant, Beatriz!

🌟Ever found yourself doubting about IBD new drugs doses? or forgetting Thiopurine metabolism details? I've been there too So I thought it could help having "IBD Cheat Sheets" and that is what I did: ibd-eii.com/ibdcheatsheet I hope it helps as much as it helps me 1/2 #IBD

Meet Dr Maryam Alkhatry who is a former President of the Emirates Gastro and #Hepatology Society and Elected President of the Pan Arab Society of #Gastroenterology for 2024. Read her article at bit.ly/4aDeyyf #WomenInMedicine #endoscopy

Early Intestinal Ultrasound Predicts Long-Term Endoscopic Response to Biologics in Ulcerative Colitis academic.oup.com/ecco-jcc/artic…

Higher serum infliximab concentrations following subcutaneous dosing are associated with deep remission in patients with #IBD @Y_ECCO_IBD @I_Blumenstein @DignassAxel @IBD_FloMD @fgomollon @DCharabaty @IBD_JohnD @alearmuzzi @RajaAtreya @charlie_lees academic.oup.com/ecco-jcc/advan…