Ian Malinow retweetledi

In large part, the ability of eggs or other high cholesterol foods to raise plasma cholesterol depends on # eggs eaten and the presence or absence of NPC1L1 (sterol influx transporter) and ABCG5/ABCG8 (sterol efflux transporter) loss of functions. Sterol hyperabsorbers (ABCG5/G8 LOF) need to watch cholesterol (and phytosterol via supplement) intake. Sterol hypoabsorbers (NPC1L1 LOF) have little worries.

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