Conan O'Brien

Check out this thing I wrote! Macrophages back at it again! Adipose tissue-resident macrophages direct fat storage in adipocytes through PDGFcc, which can be inhibited by antibodies to reduce adiposity & body weight👨‍🔬Great work from the Geissmann lab! science.sciencemag.org/content/373/65…

So you think macrophages are “just” immune cells? Well then I fear you haven’t been paying attention… Macrophages are essential regulators of the endocrine axes controlling how our bodies work. Check out this review I wrote to learn more about it 🧫🧪 sciencedirect.com/science/articl…

Microglia are the brain's resident immune cells. Their job is to patrol the brain's blood vessels looking for invading pathogens to gobble up. But what happens when they go rogue? Great article on brain-macrophages from the BBC bbc.com/future/article…

@LboroSport @lborobasketball Do you know if this game is being streamed?

It's nearly HT at the basketball down in Sir David Wallace and @lborobasketball Women's 2s have a considerable lead 👏 Loughborough 42 - 23 Oxford #BUCSBigWednesday #wherehistorybegins #bleedpurple

Habemus Doctore @OxfordDPAG ! 🎉 Congrats, Conan O'Brien 🎓 @ImmunOBrien on earning your PhD from @OxfordDPAG! It was a pleasure mentoring you on this incredible journey. Special thanks to Jeremy Taylor and Mikael Karlson for their examination of his exceptional thesis!

Circulating senescent myeloid cells infiltrate the brain and cause neurodegeneration in histiocytic disorders dlvr.it/T08X6R

Massive congratulations to @Emma_Rose_64 for getting this out before Christmas! Adipose tissue perineurial protect against obesity by promoting thermogenesis in brown adipose tissue! Super cool work and so so well earned!! 🤩👩‍🔬👏👏 See now in @ImmunityCP #neuroimmunology

@mcsinton Thanks Matthew - I enjoyed yours too!

What a fantastic #BSI23 and what a pleasure to be able to present my PhD work to such an engaged audience of immunologists! My Fitbit said I was in fat burning mode for the duration of my talk too which may help to offset some of the indulgences that followed! 👨‍🔬🔬🍺 🍔

Very tired at the last day of #BSI23 after a 5am poster presentation at the afterparty... Invite @ImmunOBrien and @Emma_Rose_64 to your parties if you want some proper immunology entertainment 😅

@ScottPLand Thanks Scott!!

Lovely talk by Conan O’Brien (not THAT one - @ImmunOBrien this one) on fat macrophages accumulating in the adrenal glands. Nice data! #BSI23. Quite a bit of discussion after too!

@AmyShergold Massive congrats Amy!! 🥳🥳 and cya soon!

This week I passed my viva meaning I have officially matured (like a preDC to cDC) and am now Dr Shergold!

@JudyRSayers @IdrmOxford @GroupRiley @OxfordDPAG Massive congrats Judy! Pint to celebrate soon!

How it started vs how it’s going… …PhD thesis submitted! ✅ @IdrmOxford @GroupRiley @OxfordDPAG #phdchat #AcademicChatter

Yet another reason why macrophages are awesome 🤩

This is pretty awesome

Great paper, yet another proof that the fixation you use for your staining can make a huge difference: just look at figures 2 and 7! science.org/doi/full/10.11…

Macrophages strike again! This time, infiltrating macrophages trigger cell death of pineal gland innervating neurons, causing functional denervation, impaired melatonin production, and sleep disruption! Not “just” immune cells! science.org/doi/10.1126/sc…

Ever wondered how dendritic cells that have never been at the site of a challenge know how to drive the right kind of T cell response? We did, and it’s finally come together! science.org/doi/10.1126/sc… @SciImmunology

Fascinating new framework for single cell seq analysis I had the pleasure of learning about from Davi himself. A particularly relevant method for understanding the functional heterogeneity of T cells - check it out!!

Is there anything macrophages don’t do??!