Immunity

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Plasma cells are the backbone of long-term antibody protection. Colin Fields & Deepta Bhattacharya explore their origins, functions, and lifespans, key to understanding lasting immunity. @uarizona hubs.ly/Q04d21Cc0

Looking forward to hosting #CSMicrobiome2026 next week in Bruges 🇧🇪 Check out the outstanding program, featuring keynote talks from Yasmine Belkaid and Michael Fischbach. See you there! hubs.li/Q04f5rkk0

Online now: NK cell dysfunction and interferon gamma production underlie autoinflammation in mevalonate kinase deficiency dlvr.it/TSJTj0

Cell Press editors Bruce Koppelman @Immunity_CP and Claudia Burrello @TrendsImmuno look forward to welcoming you in Shanghai next month to explore the fundamental aspects of immune regulation beyond disease contexts. @CellPressEvents #CSImmuneHomeostas26 hubs.li/Q04dK0hj0

What defines human pDC diversity? Our newest work led by @UlezkoAlina in @ImmunityCP uncovers a complex landscape shaped by age and tissue niche, including a cycling pDC subset that declines with age but persists in the BM & expands in malignant BPDCN. shorturl.at/99Zui

Online now: Metabolic and transcriptional plasticity supports CD8+ T cell resilience and anti-tumor immunity under nutrient stress dlvr.it/TSHg6T

Online now: Age- and tissue-dependent diversity of human plasmacytoid dendritic cells uncovers a cycling subset dominant in early life and cancer dlvr.it/TSHW39

Where memory T cells live shapes how they protect us. Thomas Burn & Laura K. Mackay reveal how tissue-resident memory T cells are spatially organized for rapid, local immunity. @UniMelb hubs.li/Q04d2KMw0

Online now: Mechanisms of inflammatory bowel diseases: Insights from human genetics and chemical biology dlvr.it/TSFqBl

Online now: An SPP1-SOCS1 pathway constrains interferon responses in tumor-associated macrophages and shapes an immunosuppressive tumor microenvironment dlvr.it/TSFlCN

Online now: Krüppel-like factor 2 programs early exhausted T cell states and restrains antiviral immunity dlvr.it/TSFbnP

Innate immune cells make lasting memories. Sarah Sun, Raúl Aguirre-Gamboa & Luis Barreiro unpack the molecular & cellular basis of trained immunity, how innate responses adapt & get stronger over time. @UChicago @Stanford hubs.ly/Q04d1ckG0

Out now! Spatial organisation of tissue-resident memory T cells. Laura Mackay & Thomas N. Burn @TheDohertyInst at The Unviersity of Melbourne report in @ImmunityCP #AAI2026 hubs.li/Q04c5-ZF0

To mark the occasion of #AAI2026, Cell Press editors have curated a special collection of cutting-edge immunology research from across their portfolio, including highlights from @CellCellPress @ImmunityCP and many more. Explore the latest insights here: hubs.li/Q04ckbWm0

Out now! Plasma cell ontogenies, functions, and lifespans. Deepta Bhattacharya & Colin A. Fields @UAZMedTucson report in @ImmunityCP #AAI2026 hubs.li/Q04c5ZRH0

Open Box Science Immunology Shaping Macrophages: Microplastics and Developmental Origin 🔹Ana Codo, @anaccodo @WeillCornell @MSKCancerCenter @ImmunityCP 📅 Thrusday, April 30 ⏰ 2 pm ET 💻 us02web.zoom.us/j/82008313506

Triple-negative breast cancer-induced palmitic acid activates neutrophils to secrete lipocalin-2, disrupting the vascular barrier in the pre-metastatic lung and thereby promoting tumor cell extravasation and metastatic colonization @ImmunityCP cell.com/immunity/fullt… 🇨🇳

Transient host-cell glycoengineering to reduce N-glycan trimming strengthens IgG-FcγRIIIa bond resilience under vascular flow forces and potentiates therapeutic antibody efficacy in lymphoma and melanoma models @ImmunityCP @LabTaia @Stanford @UWBioE cell.com/immunity/fullt…

Online now: Pharmacologic glycoengineering of Fcγ receptor IIIa enhances force-resistant IgG-FcγR interactions and anti-tumor antibody efficacy dlvr.it/TSCfRY

Online now: Palmitic acid reprograms neutrophils to compromise vascular integrity and promote breast cancer lung metastasis dlvr.it/TSCZkF