Jeremy Baskin

New paper @JCellBiol! We found a new regulator of p62 phase separation, autophagy, and antioxidant signaling — it is an E3 ligase adaptor called SHKBP1 but the effect is via direct p62 binding, not ubiquitination. Congrats to Lin Luan & team! rupress.org/jcb/article/22…

Our May issue is live! nature.com/nchembio/volum… The cover image depicts the vulnerability of the non-transcribed strand of genes to oxidized guanines and abasic sites

A new CRISPR-based genetic toolkit enables genome-wide, single-cell gene analysis in fruit flies. This will speed up gene discovery and reveal insights into brain function, development, and disease. Developed by researchers at @Cornell. Read more: bit.ly/421Ofi0

The Booker Lab at the University of Pennsylvania, in Philadelphia, and HHMI is searching for a lab manager. If interested, please apply at the HHMI link below.hhmi.wd1.myworkdayjobs.com/en-US/External…

Thrilled to welcome @mbogyo, @danetteldaniels, @SlavoffL, and Marcey Waters to @CornellChem for today’s annual Chemistry-Biology Interface Symposium!

I had a blast visiting the @omenndarlingbio @Princeton yesterday! Thanks so much to @tinakim_neuro for hosting my visit! @christhechang @KleinerLabRNA

Hello, @Princeton! Excited for my visit to @omenndarlingbio tomorrow 😃

Special day @CornellChem: welcoming back PhD alum Xiaoyu Zhang (Hening Lin lab) from @NUChemistry for a phenomenal seminar on targeted protein degradation and chemical immunology!

Methods in Enzymology, Volumes 726-728: Lipids & Membranes Vol 726: Detection by Imaging & Lipidomics sciencedirect.com/bookseries/met… Vol 727: Dynamics & Interorganelle Transport sciencedirect.com/bookseries/met… Vol 728: Metabolism, Lipidation, & Lipid-Protein Interactions: coming soon!

I've been leading a big project at Methods in Enzymology over the past year: editing back-to-back-to-back volumes describing the latest advances in methods for studying lipids and membranes — thank you to the 50 #lipidtime luminaries who contributed the 51 chapters! Details 👇

How moss makes a spiral of leaves through a rotating asymmetric division of the apical cell meristem--our paper is out @CurrentBiology today! @StraussSoe @RichardSmithLab @Joesophila cell.com/current-biolog…

A Postdoctoral Associate position is available in the Roeder Laboratory at Cornell University in Ithaca, NY with a focus on researching Polyploidy. Apply by March 1. Please spread the word. apps.hr.cornell.edu/recruiting/fac…

Too much data, too little thinking. A important essay from Ruslan Medzhitov on the importance of understanding data, not just generating it. A must read. @RMedzhitov @YaleIBIO nature.com/articles/s4157…

Lin Luan, Jeremy Baskin @basktastic et al. @weillinstitute @CornellChem identify the Cullin-3 adaptor SHKBP1 as a non-canonical regulator of p62 phase behavior limiting p62 body formation and affecting Keap1/Nrf2 antioxidant signaling. hubs.ly/Q04271ml0 #CellSignaling

Check out our new chapter in Methods in Enzymology on inhibition of #sterol protein function! Here @HoganBryceRoge1, @Laura_dta and @tomeveriss describe in detail our assay cascade to identify inhibitors of sterol transport proteins. (1/2) sciencedirect.com/science/chapte…

It was fun writing this book chapter on methods to trace #lipid metabolism. Congrats to Alec and Helene! Thanks to @basktastic for the invitation to contribute this chapter. #lipidtime @OHSUNews sciencedirect.com/science/chapte…

Membrane editing with proximity labeling reveals protein networks and mechanisms regulating lipid homeostasis in the membranes of target organelles nature.com/articles/s4158…

LipoID profiles lipid droplet interactions and identifies interorganelle regulators nature.com/articles/s4158…

Bump-and-hole engineering of xylosyltransferase isoenzymes XT1 and XT2 enables substrate profiling and modification of proteins as designer proteoglycans to modulate cellular behavior #glycotime nature.com/articles/s4158…

Janelia is hiring Group Leaders! Work alongside superstars like Luke Lavis, @JiefuBiol, @mengwang939, @JLS_Lab, @ERSchreiter. If you have ideas that are perhaps too ambitious or crazy for a traditional academic setting, that is exactly who they are looking for. Tool-builders at all career stages with original, transformative ideas for experimental approaches in imaging, molecular engineering, protein chemistry, mass spectrometry, and methods that don’t yet exist: Apply by Feb. 3, 2026: janelia.org/groupleader