John Gross Lab

UCSF Department of Pharmaceutical Chemistry is hiring faculty! Seeking candidates in #chemicalbiology, #computationalchemistry, #AI, #drugdiscovery and more. Apply now! aprecruit.ucsf.edu/JPF05273 #UCSF #QBI #FacultyJobs #academicjobs #UCSFPharmacy

End of summer, chocolate cake, and birthday celebrations.

Congratulations to Victor Lam who defended his thesis on how 'SIV/HIV-1 Vif overcomes host defenses with one small trick'

@eugenevalkov Come for sabbatical!

Interested in enzyme regulation in biological condensates? Want to live the California Dream? If yes, and yes, consider applying to our lab!

@DrP_PhD @__caro__line___ @nchesarino @memerman @ig_ech @caleighmazumaya @yifan_ucsf Thanks DAvid.

@JDGrossLab @__caro__line___ @nchesarino @memerman @ig_ech @caleighmazumaya @yifan_ucsf Congrats! I know this was a lot of work and iterations to get to this point. Excited to dig in.

Congratulations to post-doc Yen-Li Li for her work on the structure of HIV-1 Vif in complex with human A3G. A fantastic collaboration with @__caro__line___ , @nchesarino, @memerman of #FredHutch and @ig_ech, @caleighmazumaya, @yifan_ucsf of #UCSF. rdcu.be/c5bst

@ShahmoraLab @__caro__line___ @nchesarino @memerman @ig_ech @caleighmazumaya @yifan_ucsf Thank you Sarah.

@JDGrossLab @__caro__line___ @nchesarino @memerman @ig_ech @caleighmazumaya @yifan_ucsf Congratulations to the whole team!!

@SamWitus Thank you Sam.

@JenBinning @JohnGrossSF Your careful work in this area helped @JDGrossLab push the project forward.

Excited is an understatement! We finally get to see the Vif-A3G interaction. Congratulations @JohnGrossSF and Team!!

@adbelete Thanks Belete.

Congratulations @JDGrossLab. 20+ yrs later the puzzle solved. Awesome paper.

@vcluca1 @__caro__line___ @nchesarino @memerman @ig_ech @caleighmazumaya @yifan_ucsf Thanks Vince.

@JDGrossLab @__caro__line___ @nchesarino @memerman @ig_ech @caleighmazumaya @yifan_ucsf Whoa this is huge, congrats!!

Check out this review article by former graduate student Ryan Tibble dedicated to Gerhard Wagner for his 75th Birthday on the challenges and opportunities for NMR spectroscopy in biological condensates. authors.elsevier.com/sd/article/S10…

Pausing to thank everyone in the lab for a fantastic year.

We are grateful for post-docs Xi Liu @XiLiu8 and Yen-Li Li as they tackle challenging problems in host-pathogen interactions and help train the next generation of scientists in our lab. #NPAW22 #ucsfNPAW #UCSFpostdocs

Thank you @SC_in_lab and Vincent Maciej for the Preview of @JPbiochemist work that was published in Structure.

Congratulations @JPbiochemist , beautiful biochemical and structural studies of the Pox Virus mRNA decapping enzyme D9 with @JemielityLab! doi.org/10.1016/j.str.…

Celebrating Dr. Ryan Tibble's thesis research today, prompting us to think deeply about how phase separation regulates enzyme activity.

SO to @JPbiochemist for beautiful work on structure and mechanism of pox virus decapping enzyme D9 biorxiv.org/content/10.110… with fantastic cap analog chemistry from @JemielityLab.

Congratulations to lab member Leandrew Dailey who just passed his qualifying exam! Great day to celebrate with Detroit Pizza and cake from Hahdough.