Jana G Hashash, MD, MSc

@ifrahfatima @MondayNightIBD @kehutchins77 @DrFeuerstein @AdamFayeMD @ibddocmaria @DrJordanAxelrad pubmed.ncbi.nlm.nih.gov/41579011/

@MondayNightIBD 1/ 💎ASUC ✅ If pt meets Truelove & Witts ASUC criteria → admit + treat urgently. ✅ ASUC=Life-threatening medical (+potentially surgical) emergency ✅ Initial presentation in up to 10-15% of UC; occur in 15% during the course of the disease #IBD #ASUC

Let’s talk ASUC ! Management guidelines & updates ✅#Back2Basics🧵@AimenKhanMD @ifrahfatima 👇🏽 📲Join the convo w @joshsteinbergMD 3/16 🗳️CME Polls👇🏻 🆓CME👉🏼 mnibd.short.gy/25-26 Supported by educational grants @AbbVie @JNJInnovMed @TakedaPharma 📌Where are you in your🩺

@ifrahfatima @MondayNightIBD @kehutchins77 @DrFeuerstein @AdamFayeMD @ibddocmaria @DrJordanAxelrad @SophieBalzoraMD @guthealingg @ptandonGI @ibdgijami @MN_GIMD @tinahamd @JustinFieldMD @DrSamirAShah1 @YeseniaGreeff pubmed.ncbi.nlm.nih.gov/41419296/

@MondayNightIBD @kehutchins77 @JHashashMD @DrFeuerstein @AdamFayeMD @ibddocmaria @DrJordanAxelrad 2/ 📦 Initial ASUC management: 💧 IV fluids/lytes 🩸 VTE prophylaxis 🍽️ PO nutrition plan, avoid TPN 🚫 Avoid NSAIDs, minimize opioids, no antidiarrheals 💩 Send C diff, stool PCR, culture 🔦Flexsig+CMV Bx 📈 Daily BM count/bleeding/vitals/CRP ✂️surgery c/s #GITwitter #IBD

Our new CPU, published in @AGA_Gastro, suggests that prompt hospitalization should be considered for adults with severe #IBD refractory to outpatient therapy. 🔗ow.ly/blGq50Y8StX See @EdwardLoftus2’s tweetorial: ow.ly/BZnJ50Y8StY. @JHashashMD @IBDMD @ShirleyCoMekMD

@DrJordanAxelrad @DCharabaty @MondayNightIBD @abbvie @JNJInnovMed @TakedaPharma @DavidFaleckMD @fudmanMD @FunchainMD @ibdtweets @IBD_JohnD @EugeneYenMD @JeanFredericCo1 @IBDimmunology @DrsMeena @clivejmiranda @datadriven_tdoc @IBD_FloMD @MLongMD @DavidHudesmanMD @shannonchangmd @SimonHongMD @HolmerMd @DrMikeDolinger @ryanungaro @AdamFayeMD @EdwardLoftus2 @EdBarnesMD @BenClickMD @tommasoparigi @AndresYarur @ownyourcrohns @JustinFieldMD @MeganMurphyGI @AmyStewartNP @LindsayClarkeMD @KDeFelice_IBD @AimenKhanMD @EdithHoMD @IBD_DrEMF @IBDPharmD @ElisaBodenIBDMD @SalamBachour @RahulSDalalMD @md_ayanna Of course would start a different biologic (such as anti-IL or vedo) to ensure that UC stays 😴 and ⬇️🔥 with #ICI use @DCharabaty @DrJordanAxelrad @FarrayeIBD @EdwardLoftus2 @IBDimmunology pubmed.ncbi.nlm.nih.gov/34602898/

@DCharabaty @MondayNightIBD @abbvie @JNJInnovMed @TakedaPharma @DavidFaleckMD @JHashashMD @fudmanMD @FunchainMD @ibdtweets @IBD_JohnD @EugeneYenMD @JeanFredericCo1 @IBDimmunology @DrsMeena @clivejmiranda @datadriven_tdoc @IBD_FloMD @MLongMD @DavidHudesmanMD @shannonchangmd @SimonHongMD @HolmerMd @DrMikeDolinger @ryanungaro @AdamFayeMD @EdwardLoftus2 @EdBarnesMD @BenClickMD @tommasoparigi @AndresYarur @ownyourcrohns @JustinFieldMD @MeganMurphyGI @AmyStewartNP @LindsayClarkeMD @KDeFelice_IBD @AimenKhanMD @EdithHoMD @IBD_DrEMF @IBDPharmD @ElisaBodenIBDMD @SalamBachour @RahulSDalalMD @md_ayanna @ibddoctor @DrPhil_Gu @AGA_Gastro @MichaelKappel12 @JAMADerm Looks like about half of folks say continue #IFX, half on the #vedo or #IL23i train. Important Considerations: - impact of #IBD therapy on #melanoma progression/response - impact of ongoing smoldering, mild #UC - impact of #ICI therapy on #IBD

📣Join us now for a convo led by @DrJordanAxelrad @DCharabaty 🩺 How do you manage #IBD, a dx of CA & need for #immunotherapy? 🗳️#IBDPoll👇🏽, RT & share your thoughts & expertise 💬 w us ! Support by edu grants @Abbvie @JNJInnovMed @TakedaPharma

@DCharabaty @DrJordanAxelrad @MondayNightIBD @abbvie @JNJInnovMed @TakedaPharma @DavidFaleckMD @fudmanMD @FunchainMD @ibdtweets @IBD_JohnD @EugeneYenMD @JeanFredericCo1 @IBDimmunology @DrsMeena @clivejmiranda @datadriven_tdoc @IBD_FloMD @MLongMD @DavidHudesmanMD @shannonchangmd @SimonHongMD @HolmerMd @DrMikeDolinger @ryanungaro @AdamFayeMD @EdwardLoftus2 @EdBarnesMD @BenClickMD @tommasoparigi @AndresYarur @ownyourcrohns @JustinFieldMD @MeganMurphyGI @AmyStewartNP @LindsayClarkeMD @KDeFelice_IBD @AimenKhanMD @EdithHoMD @IBD_DrEMF @IBDPharmD @ElisaBodenIBDMD @SalamBachour @RahulSDalalMD @md_ayanna @ibddoctor @DrPhil_Gu I would stop #anti-TNF in a patient with #melanoma I use the table below to help guide treatment in pts with IBD who develop a malignancy cghjournal.org/article/S1542-…

@DrJordanAxelrad @MondayNightIBD @abbvie @JNJInnovMed @TakedaPharma @DavidFaleckMD @JHashashMD @fudmanMD @FunchainMD @ibdtweets @IBD_JohnD @EugeneYenMD @JeanFredericCo1 @IBDimmunology @DrsMeena @clivejmiranda @datadriven_tdoc @IBD_FloMD @MLongMD @DavidHudesmanMD @shannonchangmd @SimonHongMD @HolmerMd @DrMikeDolinger @ryanungaro @AdamFayeMD @EdwardLoftus2 @EdBarnesMD @BenClickMD @tommasoparigi @AndresYarur @ownyourcrohns @JustinFieldMD @MeganMurphyGI @AmyStewartNP @LindsayClarkeMD @KDeFelice_IBD @AimenKhanMD @EdithHoMD @IBD_DrEMF @IBDPharmD @ElisaBodenIBDMD @SalamBachour @RahulSDalalMD @md_ayanna Tough case @DrJordanAxelrad if IFX level are ok I would stop AZA to ⬇️IS- knowing that pts w IBD are at ⬆️risk of ICI-colitis, is there an advantage to optimize IFX dose to achieve a Mayo 0= Does better UC control ⬇️ risk of ICI-colitis ? @ibddoctor @IBDimmunology @DrPhil_Gu

I am grateful that @sonia_friedman and @IBDJournals honored Kim Isaacs with this piece in memoriam. Kim had such an effect on so many in our field @UNCGastro and throughout. A true mentor and friend. @MLongMD #HansHerfarth @UNCGIFellowship academic.oup.com/ibdjournal/art…

I’m #hiring. The Gubatan lab at Mayo Clinic Florida is hiring a postdoctoral research fellow to join a translational research program in inflammatory bowel disease. #IBD #Multiomics #ImmuneRepertoire #Microbiome #MachineLearning …wp-saasfaprod1.fa.ocs.oraclecloud.com/hcmUI/Candidat… @MayoClinicFLGIH

All 🫵 you need to know 🤓about 🩺🩻 evaluation and management 🩼💊💉 of Inpatient #IBD in @AmerGastroAssn @AGA_Gastro ✅Acute severe colitis ✅Small bowel obstruction ✅Intra-abdominal abscess ✅Perinal disease ‼️🚨DVT prophylaxis is critical🚨‼️ gastrojournal.org/article/S0016-…

AGA Clinical Practice Update on Inpatient Management of Adults With #IBD : Expert Review gastrojournal.org/article/S0016-… @AmerGastroAssn @AGA_Gastro Over the next couple of days I am going to summarize the recommendations of this AGA CPU by @ShirleyCoMekMD @JHashashMD @IBDMD and me 🧵

Underrated part of conferences #CCCongress26 @CrohnsColitisFn @AmerGastroAssn —- chance meetings in unexpected places @JHashashMD and I ran into @IBD_Afzali in the airport What did we talk about….. TSA being lucky in life ….and a stranger who asked us to watch his bag?!?

@PittGILiverNutr trained some folks Now they roll deep at #CCCongress2026 Thanks for all the support and mentorship @IBDimmunology and Jana!

🤔Ever wonder about role of Endoscopy in #IBD Check out recently published @AmerGastroAssn Clinical Practice Update on Role of Therapeutic Endoscopy in IBD @AGA_CGH 🎬Strictures 🗜️Fistula & abscesses ✂️Colitis associated neoplasia 🧐Surgery complications 👉link in comment

The global burden of inflammatory bowel diseases is increasing. This review summarises the latest evidence on diagnosis, staging, and management, and how to approach it in special populations #MedEd @JHashashMD @MayoClinic @jklimdi @NcaResearch bmj.com/content/391/bm…

State of the art review in IBD (December 2025; BMJ) 🫡🔢 1️⃣ Pathophysiology (+ therapeutic targets) 2️⃣ Extraintestinal manifestations 3️⃣ Mx of acute severe UC 4️⃣ Postoperative Crohn’s disease 📸: bmj.com/content/391/bm…

@oridamas @UMiamiHealth @sioannou_md Congrats!

Excited for 2026! Please join me in welcoming the newest members of our IBD team @ the #UMCrohnsandColitisCenter @UMiamiHealth

Inflammatory bowel diseases have multidimensional and often negative effects on patients’ quality of life. This review summarises the latest evidence on diagnosis, staging, prognosis, and treatments #MedEd @JHashashMD @MayoClinic @jklimdi @ncaresearch bmj.com/content/391/bm…

Team SAIA / @ibdesis wishes you a #HappyNewYear! We hope 2026 brings you & your loved ones good health & joy! 2025 was a big year for us & we are truly thankful for your support 💜 In 2026 & beyond, we will continue to address the intersection between #CultureAndGI 🙏🏽🙏🏽

The straight-line career is mostly a myth. “There was another life that I might have had, but I am having this one.” Ishiguro That line stuck with me. I wrote a personal piece about sliding-door moments, burnout and clarity, leadership when nobody is watching, and what it takes to make peace with the life you are actually living. open.substack.com/pub/charlielee…