Journal of Orthopaedic Research - Spine®

Richard D. Bell & coauthors developed a segmentation model to identify seven distinct disc tissues and to use these segmented areas, along with other derived measures, to estimate pathological changes that align with traditional histological scoring: onlinelibrary.wiley....

Timothy D. Jacobsen & coauthors found that TNFα Receptor 1 and not Receptor 2 affect annulus fibrosus and nucleus pulposus response to cytokine challenge in a rat model. Learn more in JOR Spine: onlinelibrary.wiley.com/doi/10.1002/js…

Submissions due Dec 15 for the Dr. Peter Roughley Award, presented by @OrsSpineSection. This award provides $2,000 to support travel for a mentor–trainee team conducting research in spine, disc, and cartilage biology. Learn more and apply now: ors.org/ors-dr-peter-r…

Check out this @JorSpine Editor’s Pick: Researchers tested potassium iodide (KI) as a new contrast agent to improve micro-CT imaging of the nucleus pulposus for earlier detection of IVD degeneration. Read more: bit.ly/3XyGQVk

In honor of the @KentuckyDerby this week, the #ORSSMC is excited to highlight some of the stellar Veterinary Scientists in the @orssociety, and their research in the areas of #sexdifferences, #animalhealth, & #onehealth. Stay tuned on May 1, 2, & 3 for more! #ORSxDerby #KyDerby

As ORS Social Media Committee Chair, I am excited to welcome our new Social Media Liaisons (#ORSSML)! Randeep, Nesa, Nicholas, and Ahmed will be sharing the latest @JOrthopRes and @JorSpine articles on your feed in addition to our fabulous committee members. 👏 @ORSsociety

PSA: The @ORSsociety Social Media Committee (SMC) will cross-post the latest publications from @JOrthopRes and @JORSpine across X, Bluesky, and LinkedIn. We aim to share the latest advances in orthopaedic research with you wherever you look for science content! #ORSSMC

New pub in @JorSpine: This research preliminarily illustrated the vital role of metabolic disorder in the pathogenesis of ossification of the ligamentum flavum using bioinformatic algorithms and experimental validation for metabolism-related genes buff.ly/3PKuLIF #ORSSMC

Congratulations to C3EN Joyce Chapman Community Grantee John Martin of @rushmedical on receiving a @JorSpine Early Career Research Award & a Spine Section Early-Stage Investigator Award at the @ORSsociety 7th Int'l Spine Research Symposium! Read more at c3en.org/2025/01/22/joy…

Check out @JORSpine study on mouse model for spinal ligament #ossification, simulating chronic #spinalcord compression seen in #OPLL patients. Delving into neurobio-, radiolo-, and pathological changes. Check it here: doi.org/10.1002/jsp2.1… @OrsSpineSection @ORSPCMSection

New @JORSpine study uses #Mendelian randomization to uncover causal links between inflammatory cytokines and disc degeneration. Key cytokines: #IFNγ, #IL1b, #IL4, #IL18, #SDF1a, and #GCSF show significant associations with IDD risk. > doi.org/10.1002/jsp2.1… @OrsSpineSection

A recent study by Zhang et.al. in @JorSpine developed an automated Lenke classification system utilizing innovative deep learning algorithms for preoperative evaluation of adolescent idiopathic scoliosis (AIS). #ORSSMC @ORSsociety onlinelibrary.wiley.com/doi/10.1002/js…

new research in @JORSpine! This study introduces an automated CNN technique to classify lumbar disc and facet joint health from MRI images, aiming to enhance the interrater reliability of Pfirrmann and Fujiwara grading systems. 📈🧠 👉 doi.org/10.1002/jsp2.1… @OrsSpineSection

@JORSpine is busy! New study reveals that volumetric brain measurements can predict #AIS using #MachineLearning. Random forest algorithm achieved impressive accuracy, highlighting brain regions as predictors. Read more here: doi.org/10.1002/jsp2.1… @OrsSpineSection @SRS_org

New research in @JORSpine sheds light on metabolic disorders in the pathogenesis of ossification of the ligament flavum. Using #bioinformatics , the study highlights key metabolic and immune factors involved. 🧫🔬 Check: doi.org/10.1002/jsp2.1… @OrsSpineSection #lumbarspine

New findings in @JORSpine; study performs analysis of neuromuscular junctions in bilateral paraspinal muscles of #AIS patients, highlighting neuromuscular factors as potential therapeutic targets. 💪 Read their study: doi.org/10.1002/jsp2.1… @OrsSpineSection @SRS_org

New @JORSpine report shows how compressive loading & swelling speeds up cryoprotectant delivery in IVDs; ⏫ high cell viability after cryopreservation. Big step for full disc transplantation & research! See: doi.org/10.1002/jsp2.1… @OrsSpineSection #RegenMed #Spine

New @JORSpine report shows 3-month #romosozumab treatment improves regional bone mineral density & biomechanical parameters in elderly patients with osteoporosis undergoing spine surgery. See full study: doi.org/10.1002/jsp2.1… @OrsSpineSection #spine #bone

New @JORSpine #insilico study examines different #GDF5 doses on hNP cells. 🌟 Findings: 0.25 & 1 mg doses could be effective for matrix synthesis?! Key insights for #RegenMed? Explore the study: doi.org/10.1002/jsp2.1… #Orthopedics #SpinalCare @OrsSpineSection @ORSPCMSection

New report in @JORSpine uncovers collagen damage in AF tissues of DDD patients with CHP staining. 🔍 Results show strong correlations in degradation markers, offering new insights into DDD pathology. Check it out: doi.org/10.1002/jsp2.1… #SpineCare #RegenMed @OrsSpineSection