James Lind

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James Lind

James Lind

@JamesLind1753

Scottish naval surgeon who pioneered the use of prospective controlled trials to evaluate treatments for scurvy.

Edinburgh, Scotland Katılım Mayıs 2018
141 Takip Edilen214 Takipçiler
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James Lind
James Lind@JamesLind1753·
My Library has over 1,000 primary historical Records, 250 Articles and multilingual Essays about the evolution of fair tests of treatments. I will mostly be tweeting about new accessions, and to promote the principles of fair tests of treatments. jameslindlibrary.org
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James Lind
James Lind@JamesLind1753·
Ahoy! As well as reading this article by Barbara Farrell about managing #RandomisedTrials, you can also listen to her in a podcast available at podcasts.ox.ac.uk/managing-large… #Fairtests @TestTreatments
TrialsChangLives@GoodluckJBers14

This week's reading for those wanting to know about delivering large randomised trials is Barbara Farrell's 1998 reflections on the importance of nature and nuture to their effective management #RandomisedTrials #EBHC #EBM @JamesLind1753 #NatureOrNuture pmc.ncbi.nlm.nih.gov/articles/PMC11…

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James Lind
James Lind@JamesLind1753·
Ahoy! I'm honoured to give you access to articles such as this that cannot be found outside the bound copies of a journal on library shelves. You might also like to read the article Richard Peto wrote for me about the application of his suggestions. jameslindlibrary.org/articles/refle…
TrialsChangLives@GoodluckJBers14

Here's this week's reading: Interested in getting large numbers of patients into #randomisedtrials? Read Richard Peto's reasons & methods from 47 years ago to see how relevant they remain today in Appendix on 8th page of this PDF #EBHC #EBM @JamesLind1753 jameslindlibrary.org/wp-data/upload…

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James Lind
James Lind@JamesLind1753·
Ahoy! You can also watch a video of Iain Chalmers talking with Cindy Mulrow about this research, at the Cochrane Centre in Oxford in 1993. Skip to 1:38 for the start of the interview: radar.brookes.ac.uk/radar/items/a9… @cochranecollab
TrialsChangLives@GoodluckJBers14

Here's a reading for this week: Cindy Mulrow's pivotal 1987 critique of the state of the science of medical reviews published nearly 40 years ago jameslindlibrary.org/mulrow-c-1987/ #EvidenceSynthesis #EBHC #EBM @JamesLind1753

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James Lind
James Lind@JamesLind1753·
As well as this journal article from the year 2000, I encourage you to read the one Dave Sackett wrote for me on why he became a clinician-trialist jameslindlibrary.org/articles/why-d…
TrialsChangLives@GoodluckJBers14

Something to read this week from 25 years ago: Why randomized controlled trials fail but needn't, by Dave Sackett: Failure to gain "coal-face" commitment and to use the uncertainty principle cmaj.ca/content/162/9/… #ReadAboutTrials #RCT #EBHC #EBM

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James Lind
James Lind@JamesLind1753·
Tis a modern festive custom, I am told, to curl up before a fire and watch a comforting audiovisual presentation. Instead of Love Actually, AGAIN, may I propose: 1.5hrs of @gvglass talking about the origins of meta-analysis with @FarhadShokrane youtube.com/watch?v=2RkSZS…
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James Lind
James Lind@JamesLind1753·
Listen and read about the scale and problem of publication bias with this updated Cochrane Methodology Review jameslindlibrary.org/showell-mg-col… and my essay jameslindlibrary.org/essays-essay/2…
TrialsChangLives@GoodluckJBers14

#CochraneDaily 🎧 PODCAST 🎧 In one of the last @CochraneLibrary podcasts, Marian Showell from the University of Auckland in New Zealand describes the updated Cochrane Methodology Review of publication bias, containing more than 200 studies cochrane.org/podcasts/10.10… @AucklandUni

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James Lind
James Lind@JamesLind1753·
It's 40 years since the Early Breast Cancer Trialists' Collaborative Group published its first report of its findings on treatments for women with breast cancer. I also have a record showing how this research uses fair tests jameslindlibrary.org/early-breast-c… #EBCTCG @TheLancet
TrialsChangLives@GoodluckJBers14

#CochraneDaily 40 years ago yesterday, @TheLancet published 1st report from #EBCTCG meta-analysis of individual patient data from #RandomisedTrials of treatments for women with #BreastCancer showing mortality benefits for tamoxifen and chemotherapy thelancet.com/journals/lance… #IPD

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James Lind
James Lind@JamesLind1753·
@TheEconomist @OrbisIntl @VisionSpring @ClearlyWorld This relative productivity increase was as large or larger than that reported for any other health intervention trial in LMICs. It was achieved at a total delivery cost of just US$10.20 per participant. 7/8
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Keşfet

@TestTreatments @cochranecollab @gvglass @FarhadShokrane @TheLancet @TheEconomist @OrbisIntl @VisionSpring