Jan Biegus
726 posts

Jan Biegus
@JanBiegus
MD PhD, Cardiology, Heart Failure and Intensive Cardiac Care. Wroclaw Medical University, Poland. #ESC Heart Failure Deputy Editor-in-Chief
Wrocław, Polska Katılım Mayıs 2021
283 Takip Edilen452 Takipçiler

Top trending papers in Chronic Thromboembolic Pulmonary Hypertension - Poland as a country and European Health Center Otwock, as a single centre in distinguished companionship 😀
Chronic thromboembolic pulmonary hypertension: insights from the 100 most cited papers: a bibliometric perspective
jtd.amegroups.org/article/view/1…



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Safety and efficacy of early initiation of MRA after an acute decompensated HF event or acute MI with cardiac dysfunction: a meta-analysis of RCTs. see @ESCHeartFailure see: ow.ly/M9eK50YnWW1
#ESCHeartFailure
@EJHFEiC @JanBiegus @Ppponikowski #HFA_ESC @hvanspall @ShelleyZieroth @FudimMarat @gcfmd @AlexMebazaa @MarcoMetra @GianluSava

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🗞️ #SGLT2i in heart failure. How durable is the decongestive effect?
@ESC_Journals @GiuseppeGalati_
@AmrAbdin10 @HanCardiomd
bit.ly/3OUfS9k


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Jan Biegus retweetledi

Which drugs can worsen #HeartFailure?
This #EJHF expert consensus highlights some pharmacologic pitfalls clinicians must recognize, for example:
📍NSAIDs: fluid retention
📍Antidiabetics (TZDs, some DPP4i): ⬆️risk of HF hospitalization
📍Non-DHP CCBs: negative inotropy
📍Antifungals (itraconazole, amphotericin B): myocardial toxicity, negative inotropy
📍Neuro/psych drugs (lithium, pramipexole): cause/exacerbate fluid overload
📍Some cancer treatments (e.g. Anthracyclines, HER2 targeted therapies: risk for cardiotoxicity
Read more🔗 doi.org/10.1002/ejhf.7…
@escardio @EJHFEiC
@MarcoMetra @jozinetm @AmrAbdin10 @GianluSava #HFrEF




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Global burden of heart failure due to cardiovascular diseases, 1990-2021 and predictions to 2035 based on GBD 2021 See at: ow.ly/K6sy50Y5hBX
@EJHFEiC @JanBiegus @Ppponikowski #HFA_ESC @hvanspall @ShelleyZieroth @FudimMarat @gcfmd @AlexMebazaa @MarcoMetra @GianluSava

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#GDMT implementation after revascularization in #HFrEF #IschaemicCardiomyopathy:
📍GDMT implementation was associated with lower unadjusted mortality after revascularization
📍The most favorable outcomes were seen with GDMT + CABG
📍GDMT use increased over time but remained suboptimal
Read more at @ESCHeartFailure : doi.org/10.1002/ehf2.7…
@escardio @MarcoMetra @jozinetm
#HeartFailure

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Jan Biegus retweetledi

#CardioImmunology is reshaping how we understand myo-pericardial diseases🫀
This @ESCHeartFailure article highlights that:
📍Myocardial #inflammation is observed across #myocarditis & #genetic #cardiomyopathy
📍Genetic variants such as #TTN, #DSP are reported in patients with biopsy-proven myocarditis
📍Arrhythmogenic #CMP may present with myocarditis-like inflammatory “hot phases”
📍Immune-related genetic variants are described in recurrent #pericarditis
📍Multimodal approach including imaging (#whyCMR, #ThinkPET), histology #EMB, & #genetictesting is essential
More🔗: doi.org/10.1002/ehf2.1…
#HeartFailure @escardio @ESC_Journals @MarcoMetra @_antocannata @SilCastelletti @AlbertoAimo90 @ImazioMassimo



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📌 Which medications should we avoid in HF patients ⁉️
This position 🗞️ provides a very practical guide in daily clinical practice.
📄 A must-read for clinicians caring for HF pts.
🔗 ow.ly/fwQ250XLsZW
@EJHFEiC @AmrAbdin10 @GiuseppeGalati_ @HanCardiomd #EJHF

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Why should #ODI events be included in primary outcome in #HF RCTs?
- independently assoc’d w ☠️
- inclusion can ⬆️#RCT event rates, ⬇️sample size ⬇️follow up time
- produce consistent #RRR, ⬆️#ARR
We propose a standard def’n for RCT use in this synthesis eviden.cc/48zIwEp

NEJM Evidence@NEJMEvidence
𝐉𝐮𝐬𝐭 𝐩𝐮𝐛𝐥𝐢𝐬𝐡𝐞𝐝! Clinical Trials Workshop: "Oral Diuretic Intensification as a Worsening Heart Failure Event in the Primary Outcome of Clinical Trials" by H.G.C. Van Spall (@hvanspall) et al. eviden.cc/48zIwEp @PHRIresearch #CVCT2025
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There is so much to learn from urine 💧in patients with HF!
🔑UACR
🔑urine volume
🔑urine sodium
Don’t fall behind and start measuring in your patients NOW!
Learn more from this new EJHF Expert Consensus led by @KobayashiMasa13 @JanBiegus
onlinelibrary.wiley.com/doi/10.1002/ej…

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"Worsening versus advanced #HeartFailure: Management and challenges" - Check out the article in #ESCHeartFailure ow.ly/Y8Wh50XoaB2
@EJHFEiC @JanBiegus @Ppponikowski #HFA_ESC @hvanspall @ShelleyZieroth @FudimMarat @gcfmd @AlexMebazaa @MarcoMetra @GianluSava @thiele_holger

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The #HFA_ESC Advanced Heart Failure Course returns in 2026‼️
A unique opportunity to deepen expertise in #HeartTransplantation, mechanical circulatory support, & multidisciplinary #AdvancedHF care🫀, and to engage with global experts in the field 🤝
We look forward to welcoming you to Vienna, Austria 🇦🇹, 12–13 February 2026
Register now 🔗 esc365.escardio.org/event/2071
#HeartFailure @escardio
@MajaCikes @kevin_damman @WilfriedMullens @MarcoMetra @jozinetm @h_arfsten @_antocannata @slumberbell @corneliacrm @SotiriaLiori @AmrAbdin10 @GTersalvi @GianluSava
Cornelia Margineanu@corneliacrm
📢 Registration is OPEN for the HFA Advanced HF Course 2026! 📅 12–13 Feb 2026 | 📍 Vienna, Austria 🎓 two days of immersive learning focused on advanced heart failure care—including HTx, MCS, and multidisciplinary management. 👉 esc365.escardio.org/event/2071
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💧 The Chloride Paradigm Shift in Heart Failure
From a neglected ion ➜ to a keystone of precision diuretic therapy.
🧠 Hypochloremia drives diuretic resistance, persistent congestion & worse outcomes.
🔄 New therapeutic algorithm integrating Cl⁻ into Mullens' strategy.
🆕 Collaboration🤝 @SENefrologia @secardiologia @IcyfaSemi
@ESC_Journals DOI: doi.org/10.1002/ejhf.7…


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📢 Simultaneous vaccination against influenza and respiratory syncytial virus in high-risk heart failure patients 👉ttps://doi.org/10.1002/ehf2.15432
#HeartFailure #ESCHeartFailure @EJHFEiC @JanBiegus @Ppponikowski #HFA_ESC @hvanspall @ShelleyZieroth @FudimMarat @gcfmd @AlexMebazaa @MarcoMetra @GianluSava

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Jan Biegus retweetledi

📢 Early in-hospital treatment of acute heart failure (AHF). Part 2 of the international expert opinion series on AHF management. 👉 ow.ly/mhgp50X7Im1
#HeartFailure #ESCHeartFailure @EJHFEiC @JanBiegus @Ppponikowski #HFA_ESC @hvanspall @ShelleyZieroth @FudimMarat @gcfmd @AlexMebazaa @MarcoMetra @GianluSava

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3 fantastic days of @escardio #HFA clinical trials course on HF. Fantastic faculty, lot of discussion, and time for enjoy Naples. See you next year! @_antocannata @jozinetm @HFA_President




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Acute heart failure care – a consensus series of an international experts' group
onlinelibrary.wiley.com/doi/10.1002/ej…
#EJHF @ESC_Journals
@HanCardiomd @AmrAbdin10 @GiuseppeGalati_


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Jan Biegus retweetledi

🔥New Scientific Statement from #HFA & #HFAI: SGLT2 inhibitors for the prevention & treatment of #HeartFailure
Key recommendations across the HF spectrum:
📍At risk for HF: ⬇️HF events in patients with #T2DM & #CKD, initiate #SGLT2i
📍Post-AMI: ⬇️HFh alone, consider in high-risk patients
📍Symptomatic chronic HF: ⬇️HFh & #CVdeath across LVEF, start early
📍Acute/worsening HF: early benefit on HF events & mild decongestion, initiate inpatient & have 💊 on board before discharge
📍Specific populations (#ATTRCM, #ACHD): observational data suggest safety & potential benefit
Read the full statement @ESCHeartFailure ➡️ doi.org/10.1002/ehf2.1…
#HFA_ESC #CardioX @escardio @ESC_Journals @MarcoMetra @jozinetm @GMCRosano @GianluSava


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Jan Biegus retweetledi

🌍Global opportunity alert!
The #HFA_ESC Training Grants support #heartfailure specialists to train at top international centers
Up to €10,000 for research or clinical training abroad.
📍Application deadline: Sept 30, 2025
📍Under 40 years old✅
📍HFA member required✅
📍Early career (MD/PhD)👩⚕️👨⚕️
👉Apply now: escardio.org/Education/Care…
@escardio
@MarcoMetra @jozinetm

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