@LarsVereecke @MaudeJans @magdalenakolata Congratulations, Lars and Han, and all co-authors! Beautiful work!
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Sophie Janssens Lab
68 posts
Sophie Janssens Lab
@JanssensLab
Laboratory for ER stress and Inflammation, VIB-UGent Center for Inflammation Research.
Ghent, Belgium Katılım Şubat 2020
218 Takip Edilen469 Takipçiler
🎉 Super excited to announce that our study "Colibactin-driven colon cancer requires adhesin-mediated epithelial binding" is now published in Nature! Huge congratulations to first authors @MaudeJans and @magdalenakolata for their fantastic work! 1/6🧵🎉
nature.com/articles/s4158…
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Thrilled to present our unpublished work on how dendritic cells decode LNP-embedded antigenic cargo at the @ESGCT meeting in Rome (bit overwhelmed by the amount of people though😱). For all DC and LNP lovers, come find me at 15h3O in Parallel session B.
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@JBoettcherLab @KU_Leuven Thanks a lot, Jan, for a great talk! It was fun to host you in Leuven!
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Everything set up at the @KU_Leuven Irish college for the tumor immunology and immunotherapy research day. Looking forward to for the first time present some of our unpublished work on cDC1-sensing of dying cancer cells.
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@JanssensLab @Victor_Bosteels @InflamResCen Congratulations @JanssensLab @Victor_Bosteels. Great that this is out.
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Very happy that our review in Nat Rev Imm is out! Trying to shed some light on the many knowns and even more unknowns of homeostatic dendritic cell maturation with @Victor_Bosteels @InflamResCen
Nature Rev Immunol@NatRevImmunol
Striking a balance: new perspectives on homeostatic dendritic cell maturation dlvr.it/TDLpt2
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@Victor_Bosteels @JanssensLab Hi Victor, Congratulations! Just read it, so insightful!
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Excited to share that the review article I wrote together with @JanssensLab on the latest insights in homeostatic DC maturation has just been published! Check it out here: rdcu.be/dUdp0
#DendriticCells
Nature Rev Immunol@NatRevImmunol
Striking a balance: new perspectives on homeostatic dendritic cell maturation dlvr.it/TDLpt2
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@mariska_simpson Huge congratulations Mariska, Mike and Wayne. Great work!
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I am exceptionally proud of this work. Here we address how the #UPR signal transducer IRE1 is activated by unfolded proteins. This remains an unresolved fundamental question, despite nearly thirty years of research! I hope it is well received by the #ProteinHomeostasis community.
Journal of Cell Biology@JCellBiol
Simpson, Grey, Lencer et al. @BostonChildrens find that IRE1α binds a metastable structural motif in cholera toxin and other proteins that activate the UPR with implications for how binding may be linked to IRE1α activation. hubs.la/Q02rZhbN0 #ProteinHomeostasis
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@inoagrafioti @ERC_Research 🤔 good to know, unfortunately it is still something you get to hear…luckily, we know better😉!
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On international women’s day,as someone that attended more than 500 @ERC_Research interviews in her panel,I can tell you that NO grantee has gotten her grant because she is a woman.I also celebrate today all LS1 women APPLICANTS and all LS1 women PANEL MEMBERS!You are AMAZING!🤩
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@KC_DC_01 @EFIS_Immunology @EurJImmunol @society_belgian @ugent @VIBLifeSciences Congrats, Charlie! Well deserved!
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Very honoured to receive this award from @EFIS_Immunology & @EurJImmunol 🙏 This reflects a big team effort & I’m very grateful to my mentors & team for all help, support & cool science leading to this! Also thanks to @society_belgian for nomination & @ugent @VIBLifeSciences 🥂
EFIS@EFIS_Immunology
Following the recommendation of the Gender & Diversity Task Force, the recipients of the 2023 @EurJImmunol Ita Askonas Prize awarded by EFIS are ...🥁 Dr Muzlifah Haniffa @Muzz_Haniffa Dr Charlotte Scott @KC_DC_01 Congratulations - here’s to the award ceremony at the #ECI2024!
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Super proud of this paper! We show that the thymus is more than a T cell producer, and during type 1 immunity can produce peripheral homing ILC1s! science.org/doi/10.1126/sc…
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Interested in dendritic cell biology and/or IRE1 signaling? Ready for a new challenge in the city of Ghent? If the answer is 2x yes, please check the VIB website for open positions for a PhD student jobso.id/har5 and a postdoc jobso.id/har8 in the @JanssensLab
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So now we finally know why IRE1β behaves as it does: it just needs its partner in crime, AGR2, to calm down.
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AGR2 is a pretty interesting protein, especially upon mutation of H117 to Y: this causes massive inflammatory phenotypes in patients. Turns out that the H117Y mutant is also completely incapable of blocking IRE1β activity!
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Great job by @ClootsEva and Phaedra from the Janssens lab! Happy to see their work out in @embojournal.
A fun and collaborative effort with @VIBEyckermanS and @SavvidesLab.
@VIBLifeSciences @InflamResCen
Time for a thread!
embopress.org/doi/full/10.10…
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Very proud PI with a fantastic PhD defense of @Victor_Bosteels @InflamResCen. Thanks at Caetano @ReiseSousaLab and Fabiola @Fbosorioo for coming all the way from London and Chile to join us. All the best to Victor for his new adventures in @bart_lambrecht and @ReiseSousaLab!
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📢 Join us on Dec 1st for a new #fridayseminar as we welcome Prof. Sophie Janssens @JanssensLab
from @ugent for an enlightening talk on DC maturation. Invited by @vanendert_peter
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@HiLIFE_helsinki @LifeSciHelsinki @HelsinkiUniMed It was an immense pleasure to see where my old fried and very first PhD student @Leonardo_ASouza has landed meanwhile. Thanks a lot at @HiLIFE_helsinki and especially at Leo for hosting me! Looking forward to some new collaborations!
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Welcome @JanssensLab to give a #hilifewebinars presentation.
Hybrid seminar today 23.10. at 13 (UTC+3).
👉 Biomedicum 1, Hall 2, Haartmaninkatu 8
👉 helsinki.zoom.us/j/68326277457
@LifeSciHelsinki @HelsinkiUniMed
ℹ️ helsinki.fi/en/hilife-hels…
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@HiLIFE_helsinki @LifeSciHelsinki @HelsinkiUniMed Looking forward to it! Looks like a great research place here!
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