Xu Zhou (周旭)

Beyond excited to share our #NewPaper in @CellCellPress! Inflamed environments acidify intracellular pH. BRD4 senses this via transcriptional condensates, tuning #macrophage responses to match demand and consequences of inflammation. #inflammation #pH authors.elsevier.com/sd/article/S00…

happy to share our protocol on studying pH dependent regulation of bimolecular condensates. credit to Zhongyang, Zhe, and particularly Krish from @JRTlab for imaging analysis method. Open access. no paywall. cell.com/star-protocols…

@SabanLab Very cool work! Congratulations!

We are excited to share that our team's paper is published in Immunity: "Resident tissue macrophages maintain intraocular pressure homeostasis." This work grew out of a collaboration between glaucoma clinician-scientist Katy Liu MD PhD, glaucoma physiologist W. Daniel Stamer PhD, and immunologist Daniel Saban PhD, bringing together clinical, physiological, and immunological expertise to tackle a long-standing question: does the immune system directly regulate intraocular pressure? The answer is yes. authors.elsevier.com/a/1mkeB3qNrV3V… #Glaucoma #Immunology #ResidentMacrophages #Ophthalmology #Immunity #CellPress cell.com/immunity/fullt…

@JudithAgudo1 @nyscf @parkerici @Nature Congratulation Judith!

Metastasis kills most cancer patients and grows from invisible seeds. How do these seeds escape from attack by immune cells? These seeds harness stress hormones!🤯 ⁦thanks to ⁦@nyscf⁩ ⁦@parkerici⁩ for their support. Today at ⁦@Nature⁩ nature.com/articles/s4158…

#WeekendRead! #EveryCellIsAnImmuneCell! Vollmers, Turley &co show @NatImmunol that lack of CSF1 from #skin #fibroblasts decreases macrophages dampening wound repair, and boosting fibroblast numbers! In human scleroderma this cellular circuit is altered! nature.com/articles/s4159…

@DrShrutiNaik congrats Shruti! amazing work!

Our new Nature study, lead by @yuexing identifies a brief early-life window when skin dendritic cells sense common allergens and trigger inflammation right in the skin without migrating to lymph nodes. We define this in-situ activation state as peripheral immune inducer (pii)DC, and show it emerges because of a still-maturing HPA axis and low systemic glucocorticoids. #Naiklab 👉Key takeaways: 1. Early-life immunity plays by different rules. During this window, innate responses to allergens in skin are heighted. 2. Hormones shape immunity in real time. Developmental neuroendocrine states profoundly tune how the immune system reacts, and can set the stage for inflammatory disease. Thanks our incredible collaborators @niroanandalab @EmmaGuttman @kamalkhanna @Teresalu @Amandalund and others. Our funders @NIAIDNews @NIH @DermalCell @SinaiImmunol @MSHSDerm nature.com/articles/s4158…

Final version is out, check it out! 👇👇👇

@MiriamMerad Happy New Year Miriam!

Happy New Year to all Chinese immunologists around the world. Thank you for your contributions and for pushing the field forward. Your discoveries, and collaboration strengthen our global scientific community. Wishing you health, joy, and continued breakthroughs in the year ahead

@AndrsHidalgo16 @gerardobarciap Andres, the AI section is cool!

I am excited to present our long-overdue lab website. Please visit us to learn who we are, our past work and our current lines of research! ahidalgolab.com Thank you to @gerardobarciap for his beautiful design and constant support on building it

@WeizmannScience @UriAlonWeizmann congrats Uri @UriAlonWeizmann!

Congratulations to Prof. @UriAlonWeizmann of the Department of Molecular Cell Biology, upon being awarded the 2026 IUPAP Medal for the Physics of Life

“学而不思则罔，死而不学则殆” sometime struggles with experiments, grants, manuscripts, time, mask the very reason we do science ... READ this 2-pg view from @RMedzhitov it will get juice flowing in your body again! nature.com/articles/s4157…

A fantastic innate immunity conference coming soon. Join us! youtu.be/xmQv36uYm7s?si…

Both chambers of Congress have now passed the FY26 minibus with NIH provisions. The President will sign. (1) $48.7 billion for NIH (2) Full IDC recovery (3) No more multi-year funding (4) No NIH reorganization, maintaining the current IC structure.

I am recruiting postdoctoral fellows to develop new research directions in the lab. We study transcriptional regulation through biomolecular condensates in development and disease, with an emphasis on first-principles and mechanistic discovery. Please RT or share with colleagues.

@leonard_zon @WilenLab Congrats Ryan!

Congratulations to Dr. Ryan Flynn, who has been promoted to Associate Professor at Harvard (HSCRB)! We are delighted to celebrate your achievements and look forward to your continued success.

Free tutorial: bulk RNAseq analysis from fastq to GSEA analysis (watch the full playlist) youtube.com/watch?v=Gc-Hzv…

@pascal_devant @BostonChildrens @harvardmed @PiN_Harvard @NeuroCellPress Wow! So glad to see this coming out! Congrats Anu and Meena!

Tachykinin signaling defines distinct populations of glia in the enteric nervous system. Excellent work by Anu Muppirala, Meena Rao and team @BostonChildrens @harvardmed @PiN_Harvard published today in @NeuroCellPress cell.com/neuron/fulltex…

Never miss this fantastic review on type III interferons across biological scales 🔥

2025 Sherman Prize recipient @snapper_scott reviews his team's work on the genetics associated with IBD in children. hmpgloballearningnetwork.com/site/aibdnet/v… @Gastro_Network #AIBD2025 @AIBDNetwork @BrighamWomens @BostonChildrens #crohns #ulcerativecolitis

Harvard profiles the discovery of how inflammatory caspases detect bacterial infection. And how our own lipids bind caspases in the same manner. Kudos to Anh Cao, who made these discoveries. @harvardmed @HarvardGSAS @Anh_Immunology gsas.harvard.edu/news/cracking-…

@BoXia7 @broadinstitute Congrats Bo!

What a wonderful year-end surprise! I’m deeply honored to receive the @broadinstitute's Excellence and Achievement Award in Mentorship, Teaching, or Training — especially as it was nominated by my students — at the Broad’s 21st Annual Scientific Retreat! Supporting their growth in science and careers is a true privilege, and I am incredibly proud to see all that they have achieved over the years! 🙏