Jeremy J Barr

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Jeremy J Barr

Jeremy J Barr

@JeremyJBarr

Bacteriophage biologist and enthusiast. Associate Professor at School of Biological Sciences, Monash University.

Melbourne, Victoria Katılım Mayıs 2013
834 Takip Edilen4.9K Takipçiler
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Jeremy J Barr
Jeremy J Barr@JeremyJBarr·
Very excited to share the latest work from our lab, which was published today in Nature! nature.com/articles/s4158… PhD graduate and now post-doc @SofiaDahlman, along with co-senior author Sam Forster from The Hudson, and lab members @SubDinesh
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Jeremy J Barr
Jeremy J Barr@JeremyJBarr·
Im really excited for this work as it sets up a platform for us to study, characterise, and eventually determine what impacts temperate phages may have on the human gut microbiome. Future work may even allow us to manipulate the gut using these unique viruses.
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Jeremy J Barr
Jeremy J Barr@JeremyJBarr·
- Temperate phage biology is HARD. We cant using traditional PFU plating (due to superinfection immunity), most isolates were poly-lysogens, equipment required is expensive and technically limiting, and the methods to study these phage had not been developed.
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Jeremy J Barr
Jeremy J Barr@JeremyJBarr·
This hospital-specific phage cocktail can be replicated across many institutions and pathogens, and we hope it will improve treatment outcomes for patients suffering from these multidrug-resistant bacterial pathogens.
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Jeremy J Barr
Jeremy J Barr@JeremyJBarr·
We believe this approach offers a strong middle-ground between personalised phage therapy and broader spectrum antimicrobial agents.
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Jeremy J Barr retweetledi
Brady Cress
Brady Cress@bradyfcress·
Dive into our lab’s first peer-reviewed publication—co-led with our friends @ben_a_adler and Muntathar Al-Shimary from the Doudna lab! If you’ve already read the preprint, don’t miss the new updates: doi.org/10.1038/s41564… @NatureMicrobiol
Nature Microbiology@NatureMicrobiol

📃OUT NOW Functional Genomics of Diverse Bacteriophages Enabled by RNA-Binding CRISPRi by @ben_a_adler and @bradyfcress nature.com/articles/s4156…

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Jeremy J Barr
Jeremy J Barr@JeremyJBarr·
Nature News piece on the hidden players of the gut microbiome (hint, they're phages, of course) “Our virome is hugely abundant and incredibly diverse, and we’ve looked at just a tiny percentage,” nature.com/articles/d4158…
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Jeremy J Barr retweetledi
Centre to Impact AMR
Centre to Impact AMR@CentreImpactAMR·
👏Congratulations to the VICPhage team on such an amazing achievement! VICPhage is a bench-to-bedside initiative involving #phage research & clinical product development at the Monash Phage Foundry, with phage therapy administered by the clinical team at The Alfred Hospital! #AMR
Monash Science@Monash_Science

The Award for Research Engagement and Impact goes to the VICPhage team (@JeremyJBarr, @AntonPeleg, @NandoGordillo, @SubDinesh). Their impactful work was showcased in @SBS doco 'Last Chance to Save a Life' 👏👏 Learn more about the #MonashScienceAwards 👉monash.edu/science/awards

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Paul Bollyky
Paul Bollyky@bollyky·
How are phages cleared from the bloodstream? We learned that serum factors but not neutrophils help clear phages. Thanks to Rob McBride and our terrific team of collaborators. #B33" target="_blank" rel="nofollow noopener">insight.jci.org/articles/view/…
Paul Bollyky tweet media
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