John Lee

Feeling sweet about this one 🍭 Our new STAR Protocol is out! From tolerance tests to immunofluorescence and MALDI imaging, we detail how to assess glucose homeostasis in mice 🐭 Sweet details here: star-protocols.cell.com/protocols/4560 @TeaTayaaa @Cedric_Cui @JohnDGLee

QBI welcomes Dr John Lee, our new Ross Maclean Senior Research Fellow whose translational research into motor neurone disease (MND) has already reached clinical testing. A compound he began studying during his PhD in 2009 recently completed Phase 1B trials after more than 15 years of development. He is also collaborating with a New Zealand company to design liquid drug formulations tailored for MND patients who lose the ability to swallow. The Ross Maclean Fellowship established by Jeff Maclean AM in memory of his father, Index Group founder Ross Maclean who lost his battle with MND in 2005, offers crucial support to advance these ambitious projects. “Funding is always scarce in research – this fellowship gives me the opportunity to push drug programs closer to clinical trials while also collaborating with QBI neuroscientists on new discovery-based ideas,” says Dr Lee. Read more: tinyurl.com/3j7ynf3s #UQ #QBI #MND #motorneurondisease #neuroscience #fightmnd

@Cedric_Cui @alanajulianisya @marallag_nina @IntlComplement Our wonderful students, Titaya Lerskiatiphanich, @marallag_nina, @grace_risby, and @alanajulianisya with their posters. Definitely worth comple-menting! 😎 #ICW2025 @IntlComplement

Our post-doc @Cedric_Cui, and students @alanajulianisya @marallag_nina and Austin Read had the opportunity to present their work in some oral presentations 🙌 #ICW2025 @IntlComplement

We had some great representation with @neurocomplement at the International Complement Workshop 2025! #ICW2025 @IntlComplement

Excited to announce our group leader @JohnDGLee has been awarded the Ross Maclean Senior Research Fellowship at @QldBrainInst! We are so excited to continue our research on #MotorNeuronDisease at #QBI - read more👇🏻 qbi.uq.edu.au/article/2025/0… #MND #UQ @UQ_News

Congratulations to Dr. John Lee and Prof. Simon J. Clark recipients of the 2025 Svar Complement Excellence Award, presented at the International Complement Workshop in Brisbane #ComplementSystem #ICW2025 #ComplementingLifeScience #ComplementExcellenceAward

Our group leader @JohnDGLee had the opportunity to present at @QldBrainInst yesterday 🙌 The seminar was a short (but sweet!) summary on our research in #MotorNeuroneDisease & our lab’s vision. Check out this lovely slide summarising our work - and the people behind it👇

🚨 New publication alert! Our latest study shows IL-6 trans-signalling drives TDP-43–induced inflammation in MND across both central and peripheral immune cells. 💡 Highlights a promising therapeutic target Read: doi.org/10.1016/j.bbi.… #MND #ALS @UQMedicine @FightMND

🎉 Another outstanding achievement! Our brilliant PhD student, Alana @alanajulianisya, has been recognised with the Best Poster Award at the Neuroimmunology Australia Workshop. Keep up the exceptional work on MND, Alana! 👏 #NeuroimmunologyAustralia @NeuroimmOZ #MNDResearch

Our team “Johnny Walker 4 MND Trentment” walking in support of @MNDQueensland today. A great crowd, rallying behind a vital cause! 💙 #WalkToDefeatMND #MND #ALS @UQMedicine

🎉 Exciting start to 2025! Huge congratulations to our talented PhD student, Alana Julianisya, for winning the International Complement Society @intlcomplement Early Career Cover Image Award! 🏆 Check out the stunning cover image featuring in our profile! 📸#ResearchExcellence

Speakers Posted: 17th Int'l Conference on #ComplementTherapeutics held in #Sissi, #Crete, #Greece from May 10-15, 2025 @KalimeraKriti organized by @LambrisJD @dmastellos @roumenina aegeanconferences.org/src/App/confer…

This year's Aegean Conference on Complement Therapeutics features a speaker roster that promises to engage the audience, fostering a productive scientific debate and cross-pollination of ideas across diverse disciplines. A great mix of leading experts and emerging talent in different aspects of complement biochemistry, structure-guided drug design, pathobiology and therapeutics (aegeanconferences.org/src/App/confer…). Graduate students and postdoc are strongly encouraged to submit their work and apply for our generous travel awards. We thank all of our speakers for accepting our invitation and look forward to welcoming you all to Sissi, Crete in May 2025.

Our PhD candidate Titaya presenting at last month’s UQ MND Collective Journal Club. Some thoughtful discussions about peripheral immune cells and their potential involvement in MND. Many thanks to @AndrewTosolini for organising 🙌. #MND #ALS

Congratulations to our group leader @JohnDGLee for receiving the @FightMND Bill Guest mid-career fellowship. Excited for the next 4 years ahead! 🎉👏 #MND #ALS

3/3 Our data support the outstanding work of @LionakisLab Could this cell-intrinsic complement response be harnessed using therapeutics to fight infection? We are embarking on this question now @JohnDGLee @JennyNFung @UQMedicine

2/3 Xaria demonstrates human macrophages respond bidirectionally to C5a in synergy with a multitude of pathogen molecular triggers. Surprisingly, non TLR PRRs show the greatest enhancement of cytokine release with C5a receptor activation (eg. Dectin-1 / cGAS-STING)

1/3 Excited to share our latest research by the talented Dr Xaria Li on cell-intrinsic C5a in pathogen sensing and fungal killing. Out now in PNAS @PNASNews pnas.org/doi/10.1073/pn…

Great to be attending the International Complement Workshop #ICW2023 in Newcastle upon Tyne to hear about the great advances in complement research #complementbiology Opening Teaching Day off to a good start. Congrats to all the organisers!