Jonathan Anomaly

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Jonathan Anomaly

Jonathan Anomaly

@JonathanAnomaly

https://t.co/kd5ubQYRxj

Katılım Temmuz 2022
209 Takip Edilen1.7K Takipçiler
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Jonathan Anomaly
Jonathan Anomaly@JonathanAnomaly·
1/ Today we launch an ambitious paper on the ethics of embryo screening. While the technology is new, our hopes and fears about our future children are as old as the Greek myths, including stories about Hera, goddess of fertility and the namesake of our company @herasight
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Jonathan Anomaly
Jonathan Anomaly@JonathanAnomaly·
@gtmom They’re jealous. You’ve got an amazing family
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Jonathan Anomaly
Jonathan Anomaly@JonathanAnomaly·
@ComputerEnemy @Delicious_Tacos No worries, though obviously I’m gonna get defensive since it took us four years of work with some of the top statistical geneticists in the world to achieve our scores. Plus a barrage of hit pieces by left wing extremists
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Jonathan Anomaly
Jonathan Anomaly@JonathanAnomaly·
@ComputerEnemy @Delicious_Tacos Hilarious how stupid your answer is: our r2 is 20%, and our predictor correlates at .5 with cognitive ability. It is a published paper, so you could simply look it up instead of making up numbers.
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Diana S. Fleischman
Diana S. Fleischman@sentientist·
@LizWolfeReason When I was 8 months pregnant someone took me to a members only pool with a bunch of super fit instagram influencers and I never felt prouder of my belly.
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Liz Wolfe
Liz Wolfe@LizWolfeReason·
I went Full Rihanna with both of my boys and, having lost a baby in infancy, am all the more grateful for having fully celebrated the bump. Life is very short; you simply must bellymaxx.
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Kara Kennedy@karakclairmont

On maternity clothes: older women in my family seem aghast about the thought of not trying to cover up a pregnancy bump. They think it’s more acceptable to dress in a trash bag (Cherie Blairmaxxing) than accentuate the bump at all

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Jonathan Anomaly retweetledi
Herasight
Herasight@herasight·
"Schizophrenia is too complex to screen for." That's what our client was told, so we whole-genome sequenced 7 relatives (incl one diagnosed with schizophrenia) and modelled the family history to analyze their three embryos in a way that's never been done before. Her results:
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CuatroTeitor 🦸‍♂️​
CuatroTeitor 🦸‍♂️​@CuatroTeitor·
@visegrad24 👊A ver si Trump que tanto ama a su estado 51 Venezuela va a ayudarlos hijos de toda su reputa madre, a ver si es cierto que la derecha son el amor que dicen ser. Pinches hipocritas, solo aman del pueblo lo que pueden robarle. Pero cuando suceden desgracias los abandonan.
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Visegrád 24
Visegrád 24@visegrad24·
Many people are likely buried under rubble after the powerful double earthquakes in Venezuela. International help and quick arrival of numerous search teams is desperately needed.
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Jonathan Anomaly
Jonathan Anomaly@JonathanAnomaly·
@cremieuxrecueil My only worry about GLP-1s is that if men take them instead of hitting the gym, they will end up with lower testosterone and become physically and psychologically weak, which correlates with lots of bad social outcomes
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Crémieux
Crémieux@cremieuxrecueil·
Daily whitepill: The obesity crisis is ending, and after years of plumping up, America is finally getting thinner.
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Jonathan Anomaly
Jonathan Anomaly@JonathanAnomaly·
Really enjoyed this one!
Daniel Shur@teleodaniel

Had @JonathanAnomaly on the podcast to discuss @herasight and the ethics of selecting embryos for intelligence, height, and other traits. We get into radical life extension, and the broader philosophy of seeking ever greater control over biology. Jonathan shares a polarizing and inspiring view of what humanity can become. 0:00 Selecting embryos for intelligence and the taboo around it 7:39 Aging, death and status quo bias 14:29 Side effects of secularization 17:29 How a preference cascade will shift the Overton Window 22:40 The importance of biological intelligence post-AGI 29:53 In vitro gametogenesis, gene editing & fully synthetic human genomes 38:14 The rift between us and the upcoming enhanced generation 43:26 Nietzsche’s Übermensch, slave morality, and transhumanism 56:32 Longevity as our generation’s space race Look up Free Radicals podcast on Spotify, Apple Podcasts, YouTube, etc. Follow me and @EricDai_BioE for weekly episodes. Thank you to @SynBioBeta for hosting us!

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Jonathan Anomaly
Jonathan Anomaly@JonathanAnomaly·
@razibkhan As usual, value of personality traits underestimated relative to IQ
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Jonathan Anomaly
Jonathan Anomaly@JonathanAnomaly·
@m_goes_distance @JimRice1111 @herasight Also worth noting: IVF varies considerably based on age, and even who your doctor is. One problem with stats in this area is that traditionally people doing IVF were old and infertile. But if you do it electively and at a younger age, you often get far higher yields
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Mgoes (bio/acc 🤖💉)
Mgoes (bio/acc 🤖💉)@m_goes_distance·
most people have no idea this is happening "we're the first company to do IQ testing on embryos a couple hundred customers already, babies already born, and the cost is only going down from here" (ft @JonathanAnomaly from @herasight )
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Jonathan Anomaly
Jonathan Anomaly@JonathanAnomaly·
@akarlin Probably also why so many doctors have paternalistic attitudes. They see a lot of unstable patients
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Anatoly Karlin 🧲💯
Anatoly Karlin 🧲💯@akarlin·
Just had the thought that doctors have to deal with an absurd amount of hypochondriacs. This must be why they are so obsessed with patient "freakouts". What comes off as "freak" occurrences to us occupies an inordinate share of their mental space just through selection effects.
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mickey friedman
mickey friedman@mickeyxfriedman·
it doesn’t surprise me at all that Nabokov had synesthesia i wonder how he colored the L’s and T’s in ‘Light of my life, fire of my loins. My sin, my soul. Lo-lee-ta: the tip of the tongue taking a trip of three steps down the palate to tap, at three, on the teeth. Lo. Lee. Ta’ can only imagine, but pretty cool that you can hear the way his mind works through his writing, in a way
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Jonathan Anomaly retweetledi
Surf Life 🏄
Surf Life 🏄@surfgoldbeaches·
You know what’s coming, but you still can’t look away.
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Jonathan Anomaly
Jonathan Anomaly@JonathanAnomaly·
@ToKTeacher @m_goes_distance Can’t IQ test an embryo any more than you can give it a breast cancer exam. Instead, you can sequence the embryo and use polygenic risk scores to make predictions about traits like height, IQ, or liability to diseases like breast cancer
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Mgoes (bio/acc 🤖💉)
Mgoes (bio/acc 🤖💉)@m_goes_distance·
99.99th Percentile IQ Embryo Selected. What does it all mean? @JonathanAnomaly explains how polygenic embryo selection is moving from science fiction into reality. And why the biggest barrier may no longer be technology, but culture. 00:00 - Viral IQ Embryo & Eugenics 07:10 - PGT Adoption 11:20 - Will Governments Ban This? 15:30 - Fertility Decline & Genetic Selection 21:30 - How Accurate? 28:50 - The Heritability Ceiling 35:20 - Autism, Neurodivergence 37:30 - A Genetic Vaccine 42:40 - PGT Skepticism 48:05 - Dangers of Pleiotropy 55:05 - The Adoption Curve 58:30 - Future of IVF 1:06:00 - Pronatalists & The Future 1:11:10 - Embryo Selection vs Editing 1:17:30 - Building Better Humans
Gene Smith@GeneSmi96946389

A friend of mine had her embryos screened by Herasight and they found one with an IQ score in the 99.99th percentile

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lamide
lamide@skithedream_·
Can't believe he survived the blast out
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Jonathan Anomaly
Jonathan Anomaly@JonathanAnomaly·
@forbiddenmerch Now do this for Anglos. They are, by far, the biggest advocates of mass migration in every country they occupy and govern
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Ryan
Ryan@forbiddenmerch·
"The white race is the cancer of human history." Jewish activist Susan Sontag ✡️
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Keşfet

@gtmom @ComputerEnemy @Delicious_Tacos @sentientist @LizWolfeReason @CuatroTeitor @visegrad24 @cremieuxrecueil