John R. Ussher

@Amurtab @UAlberta_Pharm 7) For anyone interested in using PSSI-51 as a tool to manipulate #ketone #metabolism #oxidation for their studies, we are happy to share and please just reach out to myself or @Amurtab

@Amurtab @UAlberta_Pharm 6) So grateful to all @Amurtab hard work and to our many collaborators who helped this paper happen , but a special shoutout to Dr. Dion Brocks @UAlberta_Pharm , whose lab developed the assay for us to detect/measure PSSI-51 in biological specimens

This will likely be my last thread here as I’m moving over to Bluesky (bsky.app/profile/jusshe…), but wanted to share exciting work from former PDF @Amurtab @UAlberta_Pharm ; cell.com/iscience/pdf/S…

I cannot articulate in the form it truly deserves how much he has impacted my life, but I know I would not be who I am today, or where I am today, if not for him, which I know extends to many others here at the UofA

This is a very difficult msg for me to type, but it is with deep sadness that I share news regarding the passing of Dr. Gary Lopaschuk, who was not only my mentor, but a dear friend these past 20 years. pediatrics.cmail20.com/t/d-e-sdltux-l…

Our LinkedIn page is now live! Give us a follow to stay up to date with all things SHVM 2025 and beyond #longlivemetabolism #SHVM 👇 linkedin.com/company/shvm

Stay tuned for further updates as we near the 22nd Annual SHVM meeting: Shedding Light on Emerging Metabolic Targets in Cardiovascular Diseases 🫀 Abstract submission 17 March 2025 Early bird registration 18 April 2025 Registration and payment deadline 15 May 2025

@HanKimLab @Yena__Oh @OttawaCmm @UOHIResearch @ssol_kw @termehaslani @RimshahAbid @WenbinLiang2 @PeterPLiu_MD @StephIrisPro Congrats!!!

Big day for Han Kim Lab! Huge congratulations to Dr. Oh @Yena__Oh on successfully defending her PhD! 🥳👏 So proud of your achievement and grateful to have worked with you as our first PhD student. @OttawaCmm @UOHIResearch

A big CONGRATS to @JordanSFChan , who successfully passed his #CandidacyExam this morning! Really proud seeing how much he has matured as a #scientist since joining the lab May 2021

I'm looking to hire a fully funded PhD student this year. If you are interested in investigating mitochondrial bioenergetics in diverse tissues please reach out.

Excited to share my work with @DanielJDrucker on the role for GIPR agonism alone and with GLP-1R agonism (@tirzepatide_ ) in the regulation of gut inflammation, and providing new insights on the localization of the GIP receptor in the gut. See paper here: insight.jci.org/articles/view/…

Finally the latest baby of the Quebec PAH and vascular biology research group is out 😎. Congrats Dr Grobs @Grobs4 @3CPRCouncil @PVRI @ATS_PC @PullamsettiL @Savai_Lab @facmedUL science.org/doi/10.1126/sc…

Using multiple techniques the authors affirm that Gfral expression is overwhelmingly restricted to the brainstem in healthy mice @MolMetab @cusm_muhc @seeleyrj sciencedirect.com/science/articl…

Check our last review in the special issue of Essays in Biochemistry on AMPK and AMPK-related kinase👉AMPK and O-GlcNAcylation: interplay in cardiac pathologies and heart failure portlandpress.com/essaysbiochem/… @ISHR_ES @escardio @GRRC_SFCardio

The SUMMIT trial Tirzepatide for #HeartFailure with Preserved Ejection Fraction in PPL with #Obesity A lower risk of a composite of death from cardiovascular causes or worsening heart failure nejm.org/doi/full/10.10…