Keyan Li

Do ‘gasotransmitters’ need to be gases? Andy makes the case in Redox Biology for Protic Small Molecule Bioregulators (PSMBs): a cross-cutting class of small molecules where protonation states impact biological speciation, permeability, & action. @agdavis98 doi.org/10.1016/j.redo…

Excited to share this work with wundergrad Addison in @angew_chem where we showcase the synthetic utility of contact-ion stabilized RSSe- for metal thioselenides, the use of 77Se NMR to probe S-Se bond polarization, and insights into thiolate persulfidation on nucleophilicity

Hydrogen cyanide (HCN) is the newest gasotransmitter & a key protic small molecule bioregulator. We developed a platform approach to develop & deploy biocompatible responsive chemical tools for HCN delivery. Check out Mike's paper in @angew_chem! onlinelibrary.wiley.com/doi/10.1002/an…

Nitrogen Subvalency in a Four-Member Redox Series of Iron–Sulfur Cluster Imido Complexes | Journal of the American Chemical Society @ChemistryMIT @MIT pubs.acs.org/doi/10.1021/ja…

New Chem Commun paper on Cys-activated H2Se delivery from isoselenocyanates. Includes mechanistic insights, solution characterization, and cell imaging. Great work Reis, Keyan, Christopher, Arman, Turner, & Kaylin! pubs.rsc.org/en/content/art…

New ACS Chem Biol paper out: No H2S needed - We show that an increasingly common approach for H2S detection actual reports on thiols and esterases. Nice work Haley (@hsmith922), Aleanna, Christopher, & Ally sorting out the chemistry of this system! pubs.acs.org/doi/10.1021/ac…

Another contribution from our research group on the catalytic reduction of nitrite: A Mononitrosyl Diiron(II) Compound Catalyzes the Reduction of Nitrite to Nitric Oxide | Inorganic Chemistry pubs.acs.org/doi/10.1021/ac…

Glad to see our latest work out in @InorgChem ! Check it out if you are interested in reactive sulfur species detection and crosstalk with NO.

New @InorgChem paper: Mo/W-CO complexes + S₈ → COS! Highlights links between CO & reactive S species (Se behaves differently!) Initial 2023 @ChemRxiv preprint, now w COS quantification & new insights. Great work Toby, Haley & Keyan! @hsmith922 @keyanl10 pubs.acs.org/doi/10.1021/ac…

Congrats to all the UO graduates today, including Andy & Haley! Dr. @agdavis98 & Dr. @hsmith922

Check out Shiva’s @ChemicalScience paper on using in situ ReactIR to measure host-guest binding affinities across hydrogen and halogen-bonding #supramolecular systems. Can be used w/ host or guest vibrations to measure Ka values. Great work @ShivaMoaven! pubs.rsc.org/en/content/art…

Congratulations Dr. Smith @hsmith922 on a great PhD defense! Thanks for all your work expanding our understanding of COS biological chemistry!

Congratulations Dr. Davis @agdavis98 on a great PhD defense! Lots of new insights into the reactivity and binding of reactive hybrid S & N anions!

Two upcoming defenses in our lab this week from Andy (@agdavis98) & Haley (@hsmith922)!

Upcoming Thesis Defense - Andy Davis, Pluth Lab - Wednesday, May 7th @ 10am in 276 Education and via Zoom tinyurl.com/4mc5fx58

Mike was one of 3 UO faculty selected in the 2025 class of Senior Members of the National Academy of Inventors! Way to go Mike (@mdpluth), Ramesh Jasti (@profjasti), & Karen Guillemin! news.uoregon.edu/academy-names-…

Check out Andy’s new @InorgChem paper on reactive S & N anions binding to molecular receptors! Lots of NMR data & X-ray structures highlighting the importance of C-H interactions in reversible HS- (and other anion) binding. Great work @agdavis98 ! pubs.acs.org/doi/10.1021/ac…

George Sheldrick will be missed🕯️🕯️🕯️#SHELX @IUCr #crystallography #education

Intermolecular N–N Coupling of a Dinitrosyl Iron Complex Induced by Hydrogen Bond Donors in the Secondary Coordination Sphere | Journal of the American Chemical Society @WWU pubs.acs.org/doi/10.1021/ja…

Thank you @JonathanLKuo for meeting @uoCHandBIC students and for a fantastic @uoadse seminar last week sharing your passion for new ligand designs, tautomerism, and hydrogen bonds!