Pluth Group

(1/2) Our awesome Chemistry and Biochemistry graduate students represented us at the Chemical Biology and Physiology Conference 2025 in Portland, Oregon last week. Go Ducks!🦆 @v_derose @PluthGroup @uoCHandBIC @Gaby_Bailey_6 @Katelyn_alley14

Do ‘gasotransmitters’ need to be gases? Andy makes the case in Redox Biology for Protic Small Molecule Bioregulators (PSMBs): a cross-cutting class of small molecules where protonation states impact biological speciation, permeability, & action. @agdavis98 doi.org/10.1016/j.redo…

Curious about the impacts of Lewis acids on persulfide & thioselenide chemistry? Check out Keyan & Addison’s paper using isolated ZnSSR & ZnSeSR complexes to directly study reactivity. Lots of insights from 77Se NMR & XRD! @keyanl10 @angew_chem onlinelibrary.wiley.com/doi/10.1002/an…

Hydrogen cyanide (HCN) is the newest gasotransmitter & a key protic small molecule bioregulator. We developed a platform approach to develop & deploy biocompatible responsive chemical tools for HCN delivery. Check out Mike's paper in @angew_chem! onlinelibrary.wiley.com/doi/10.1002/an…

🎃🎃Happy Halloween from the Pluth Lab! 🦇🦇

New Chem Commun paper on Cys-activated H2Se delivery from isoselenocyanates. Includes mechanistic insights, solution characterization, and cell imaging. Great work Reis, Keyan, Christopher, Arman, Turner, & Kaylin! pubs.rsc.org/en/content/art…

New ACS Chem Biol paper out: No H2S needed - We show that an increasingly common approach for H2S detection actual reports on thiols and esterases. Nice work Haley (@hsmith922), Aleanna, Christopher, & Ally sorting out the chemistry of this system! pubs.acs.org/doi/10.1021/ac…

Congratulations to the 2025 recipients of the Chemistry and Biochemistry Graduate Student Teaching Awards: Sylvia Kennerly, Marie Kerns, Natalie Lakanen, Keyan Li, Rohan Myers, and Dario Nunez! tinyurl.com/yk8cydkp

@amit_IACS @SayanAtta95 We're happy to have Sayan here in Eugene!

I am happy to share the news that my student Dr. Sayan Atta @SayanAtta95 has joined @PluthGroup for postdoctoral research.

Check out our @InorgChem paper on Fe-NO formation from Fe(II) w/ SSNO(-) & SNO(-)! New insights into metal nitrosyl & reactive sulfur species formation from small S/N hybrid molecules. Great work Keyan (@Keyanl10), Juan, and George! pubs.acs.org/doi/10.1021/ac…

New @InorgChem paper: Mo/W-CO complexes + S₈ → COS! Highlights links between CO & reactive S species (Se behaves differently!) Initial 2023 @ChemRxiv preprint, now w COS quantification & new insights. Great work Toby, Haley & Keyan! @hsmith922 @keyanl10 pubs.acs.org/doi/10.1021/ac…

Congrats to all the UO graduates today, including Andy & Haley! Dr. @agdavis98 & Dr. @hsmith922

If you're at the UO Undergraduate Research Symposium, go check out the great work by Addison & Aleanna!

Check out Shiva’s @ChemicalScience paper on using in situ ReactIR to measure host-guest binding affinities across hydrogen and halogen-bonding #supramolecular systems. Can be used w/ host or guest vibrations to measure Ka values. Great work @ShivaMoaven! pubs.rsc.org/en/content/art…

Congratulations Dr. Smith @hsmith922 on a great PhD defense! Thanks for all your work expanding our understanding of COS biological chemistry!

Honored to receive the UO CAS Collegiate Faculty Award! Thanks @uocas for this recognition, and for recognizing the research contributions, creativity, and innovation from @PluthGroup members! cas.uoregon.edu/two-natural-sc…

Congratulations Dr. Davis @agdavis98 on a great PhD defense! Lots of new insights into the reactivity and binding of reactive hybrid S & N anions!

Two upcoming defenses in our lab this week from Andy (@agdavis98) & Haley (@hsmith922)!

Mike was one of 3 UO faculty selected in the 2025 class of Senior Members of the National Academy of Inventors! Way to go Mike (@mdpluth), Ramesh Jasti (@profjasti), & Karen Guillemin! news.uoregon.edu/academy-names-…

Check out Andy’s new @InorgChem paper on reactive S & N anions binding to molecular receptors! Lots of NMR data & X-ray structures highlighting the importance of C-H interactions in reversible HS- (and other anion) binding. Great work @agdavis98 ! pubs.acs.org/doi/10.1021/ac…