Michael Kharas MSK
943 posts

Michael Kharas MSK
@KharasLab
Michael Kharas PhD is a Member in Molecular Pharmacology at the Sloan Kettering Institute. Tweets are my views alone not MSKCC.
New York City Katılım Eylül 2011
419 Takip Edilen1.9K Takipçiler

Excited to announce a paper out today in @natgenet.nature.com identifying an approach to mitigate the risk of therapy-related myeloid malignancies in patients with cancer. Collaboration with @KellyLBolton @WashU and led by @IrenaeusChan & @PuZhang09980432
nature.com/articles/s4158…
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After almost 13 years I am stepping down from the helm of the Department of Pathology @nyugrossman. It was a privilege and a pleasure to contribute to the creation of one of the most exciting Pathology Departments in the US and to work with fantastic colleagues, pathologists, research scientists, staff and trainees. During this exciting period, the department of Pathology almost tripled its faculty numbers, clinical and research (grant) revenue and invested heavily in a state-of-the-art molecular pathology lab, the growth of molecular microbiology, the expansion and automation of our clinical labs, and the integration of new digital and artificial intelligence tools that are redefining how our pathologists diagnose disease. We are now one of the few departments with ~100% slide digitization and a fully digital sign out. At the same time, the department’s research profile has increased significantly with the recruitment of leaders in the areas of immunology, cancer biology, computational science as well as world-renowned pathologists and physician-scientists. On a personal level, I was blessed to be thrown in deep water early in my life and bet on the talent and brilliance of colleagues who helped me set the foundation for a truly integrated and modern Pathology Department. I remain here to aid the transition of leadership, excited to spend more time in my own research laboratory and soon take up new challenges...@NYUGSOM_Path

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Michael Kharas MSK retweetledi

On the cover of this month's issue of Nature Nanotechnology! Our nanosensor + AI-based liquid biopsy (blood test) for brain tumors that also enables the discovery of new biomarkers. nature.com/articles/s4156…

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Hello everyone! We're participating in @Cycle4Survival to raise money for rare cancer research at @MSKCancerCenter, and your support would mean so much to us. Make a 100% tax-deductible donation using the link. Thank you! secure2.convio.net/mskcc/site/TR?…
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Michael Kharas MSK retweetledi

Researchers @MSKCancerCenter @WeillCornell Discover PGBD5 Guides Normal Brain Development in Addition to Causing Cancers mskcc.org/news/researche…
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@ScienceAdvances @KentsisResearch Congrats Alex!! Amazing to see this story out!! Love the cover!!!
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Michael Kharas MSK retweetledi

Researchers identify PGBD5, a transposase-derived gene, as an essential regulator of normal brain development in mice and humans.
Learn more in this week’s issue of Science Advances: scim.ag/4pGsjT8

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@bloodgenes @GauravA_UK @KharasLab @ScienceMagazine @broadinstitute @hhmi_science @BostonChildrens @DanaFarberNews @DanaFarber Congrats!! Awesome story!!
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Delighted to have our work on 🧬 resilience to 🩸cancer led by @GauravA_UK & amazing collaborators, including @KharasLab, published in @ScienceMagazine: science.org/doi/10.1126/sc… 🧵

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Michael Kharas MSK retweetledi

People with TP53 mutations have blood stem cell clones (CHIP) which promote chronic inflammation, aging, and risk of blood cancers. This can be blocked by multiple means (as shown below) to potentially prevent cancer, but CHIP is not assayed in the clinic.
jci.org/articles/view/… @jclinicalinvest

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Michael Kharas MSK retweetledi

Scientists have known for decades that there are gene mutations that increase your risk of developing cancer. But there is also a genetic variant that could reduce the risk of developing certain #bloodcancers, according to new research co-led by scientists from MSK.
“We’ve discovered the mechanism by which a change within the MUSASHI2 (MSI2) gene region appears to protect people from blood cancers related to clonal hematopoiesis,” says cancer biologist @KharasLab, a member of the Molecular Pharmacology Program in the Sloan Kettering Institute and co-corresponding author of the paper.
Learn more: bit.ly/3N0Vxyt

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@LeeGrimesLab @GauravA_UK @bloodgenes @_ruslansoldatov @AbdelWahablab @AlexBickMDPhD Thanks so much Lee!!!
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@KharasLab @GauravA_UK @bloodgenes @_ruslansoldatov @AbdelWahablab @AlexBickMDPhD very cool. Congrats.
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Check out our latest story science.org/doi/10.1126/sc…! Huge thanks to @GauravA_UK and the @bloodgenes lab for driving this work forward together with us. This was a great team effort with outstanding collaborators @_ruslansoldatov, @AbdelWahablab, and @AlexBickMDPhD.
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I don't share much personal info here, but I’m proud that my daughter, Stella Trout, returns to the Alex Trebek Stage for #Jeopardy! on Monday, Jan 5. After becoming a champion in June 2025, she's competing in the Champions Wildcard Tournament. Follow the bracket 👇 and tune in!

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@bloodgenes @GauravA_UK @KharasLab @ScienceMagazine @broadinstitute @hhmi_science @BostonChildrens @DanaFarberNews @DanaFarber Beautiful work and a tour de force. Congrats Vijay, Mike & team!
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@KharasLab @GauravA_UK @bloodgenes @_ruslansoldatov @AbdelWahablab @AlexBickMDPhD Congratulations Mike & Vijay!
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Michael Kharas MSK retweetledi

In Memoriam: Bayard D. Clarkson, MD: aacr.org/professionals/…
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@KharasLab @GauravA_UK @bloodgenes @_ruslansoldatov @AbdelWahablab @AlexBickMDPhD Many congratulations, Dr. Kharas!
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@KharasLab @GauravA_UK @bloodgenes @_ruslansoldatov @AbdelWahablab @AlexBickMDPhD Great work! Congrats Mike @bloodgenes and all!
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@KharasLab @GauravA_UK @bloodgenes @_ruslansoldatov @AbdelWahablab @AlexBickMDPhD Congrats Michael, Vijay & team! Very cool -- Musashi strikes again!
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Thanks to Julie Grisham at @MSKCC for covering our latest story! Check it out here: mskcc.org/news/new-resea…
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