Matt Kozlov

"Khamenei out as Supreme Leader of Iran by…" With US and Israeli strikes now underway, three prediction sources are pricing the probability of regime change. One was ahead of the other two. ——— 🔵 Kalshi (human-traded, by Sep 1): Flat at ~48-50 all week. Spikes to 64 on the strikes. ⚪ Polymarket (human-traded, by Dec 31): Flat at ~48-50 all week. Spikes to 74 on the strikes. 🔴 Vico (AI-powered, by Dec 31): Steady climb from ~65 to 78.5 over 10 days — pricing in the escalation before most humans were trading it. ——— The human-traded markets sat still while diplomacy played out. Vico's AI models were reading the buildup — carrier deployments, military surges, failed talks — and adjusting daily. In this instance, the crowd moved on the headline and the AI moved on the signal.

@pitdesi Check out @TassoInc

After four failed blood draws on my wife this week (she has challenging veins), I’m wondering if Theranos would have solved this eventually…

@alexiskold Congrats @alexiskold !!!

I am thrilled to share that we raised an oversubscribed $82M Fund III to lead pre-seed and seed rounds in Vertical AI, Deep Tech, Healthcare and Biotech startups in NYC and Boston. To be exact, we raised $82,048,000 - a number that felt on-brand for a nerdy firm like ours that loves riddles, the future, Morse code, and Easter eggs. We are immensely grateful to our LPs for their ongoing belief in our strategy and approach. We are equally grateful to the founders who have chosen to partner with us. Here is 2048 Ventures Ventures Fund III in a nutshell: - We back exceptional, ultra-competitive, visionary founders. - We lead pre-seed and seed rounds with $500K - $3M checks. - We invest in Vertical AI, Deep Tech, Healthcare and Biotech. - We invest primarily in NYC and Boston. - We seek businesses with strong data moats. Read more about where we’re excited to invest: 2048.vc/blog/2048-vent… If you are a builder and visionary looking for the highest conviction first-check investor, please reach out or re-share with your network!

Seasats (Techstars 2021), a leading developer of long-endurance autonomous surface vessels, was selected by the Department of War to receive a $24M award under the Accelerate the Procurement and Fielding of Innovative Technologies program. The $24M award, made by recommendation of the U.S. Navy and U.S Marine Corps, will accelerate procurement, production, and scaling of Seasats' technologies, delivering advanced maritime capabilities at reduced costs. Massive congratulations to the team!

Hydrosat raises $60 million in Series B funding spacenews.com/hydrosat-raise…

From university research to orbit 🚀. Preesha Kumar’s @asunews feature spotlights Solestial’s journey from @ASU MacroTechnology Works to space. Read how Solestial is scaling its radiation-hardened silicon solar technology: bit.ly/48H59p3

Catalyx Space (Techstars 2024), a space infrastructure company providing turnkey solutions for orbital missions, raised $5.4M. 🪐 The new funds will support the commercialization of its reentry architecture, the expansion of overseas operations, and global customer growth. Founded in 2024 by Rifath Shaarook and Saqib Hussain, Catalyx was born out of his frustration with the slow, fragmented infrastructure of the space industry. The company’s mission is to make orbital access rapid, reliable, and affordable for sectors like defense, advanced manufacturing, and biopharma. 🔗 tsta.rs/xY1z50XqfxB

@awaisahmedna Mazel tov, Awais!!!

Mission status: Launched. Mission duration: Lifetime. ✨

Excited to share Mitsubishi Electric's press release announcing its investment in Solestial! mitsubishielectric.com/en/pr/2025/052…

@zeno_power Congrats @zeno_power!!! Super exciting! Proud to be part of the journey with you.

Today, we’re announcing our $50 million Series B and that Admiral John M. Richardson (USN, Ret.), former Chief of Naval Operations, is joining our Board of Directors. With over $70 million raised to date, we’re accelerating toward full-scale nuclear battery demonstrations in 2026, enabling deliveries to maritime and space customers in 2027. Read more via @demarest_colin in @axios: axios.com/2025/05/14/zen…

The launch was epic. The first light was sublime. Commercial imaging begins May 1st! Super exciting times @PixxelSpace!

And God said, Let there be light: and there was light. And God saw the light, and it was good. 💥 Excited to reveal first light images from all 3 of the Fireflies that launched recently! A new era in earth observation begins now.

A tiny Colossal woolly mouse is the key to the de-extinction of a woolly mammoth? Uhm…say what? With seven edited genes, this tiny pioneer exhibits mammoth-like traits, including golden fur and cold resistance. Watch as Dr. Beth Shapiro explains how this breakthrough is a tiny step toward the de-extinction of the mammoth 🦣 #SXSW

When people (usually LPs) tell me how capital intensive hardware is I ask them how much their favorite software company has raised. I'm glad someone made the table. It isn't that hardware isn't capital intensive, it's that software is regularly _even more_ capital intensive.

I support the Mensarius Oath for ethical investing created by @govclab vcl.to/mensarius #MensariusOath

@naywilliams @UnionLabs @altosvc @andrew_antonio @AnnieLeChelman @chrisbkim @catapultseed @TenOne10 @LererHippeau @NewStackVC @LavrockVC @Techstars Thanks man! Love all the great folks helping these guys soar!

@UnionLabs @altosvc @andrew_antonio @AnnieLeChelman @chrisbkim @catapultseed @TenOne10 @LererHippeau @NewStackVC @LavrockVC @Techstars Special shout out to @Koz for making the intro to me back at pre-seed. Amazing Founders and one of the best BoDs I've been a part of. Onward! 🙏

Our #portco raises $30M Series B led by @altosvc !! Congrats to @andrew_antonio and the full team at Urban Sky! 🎈 @naywilliams @AnnieLeChelman @chrisbkim

@jefielding Dinosaurs. My MRI came on a CD-ROM. Come on Mt. Sinai. At least meet us in 1996!

Wish I was joking but… I needed to get the X-rays they took of my shoulder in the ER over to my orthopedist and they told me to come pick up a ‘floppy disk’ with the images. ER is Mt Sinai in NYC, they use Epic. Ortho is at NYU. Founders + investor, please keep investing in healthcare solutions - we need to fix this.

India's first private satellite constellation by @PixxelSpace showcases the exceptional talent of India's youth and highlights the expanding capabilities of our private sector in the space industry.

18 intense sleepless hours, countless adjustments, and one incredible outcome: all 3 satellites are alive and working in space. Solar panels deployed and satellites reliably sun pointing, all satellites detumbled successfully, and seamless two way communications working like a charm. From here, it only gets more exciting. Couldn’t be prouder of this team!