Kyosuke Yakabe

I am happy to share our work that came out in Nature Microbiology @NatureMicrobiol 'Acarbose redirects gut microbiome utilization of dietary carbohydrates to suppress anaphylaxis in mice' nature.com/articles/s4156…

@Kazu_Kasahara @NatureMicrobiol Thank you!😊

@KyosukeYakabe @NatureMicrobiol Huge congrats!!🎊

I am happy to share our work that came out in Nature Microbiology @NatureMicrobiol 'Acarbose redirects gut microbiome utilization of dietary carbohydrates to suppress anaphylaxis in mice' nature.com/articles/s4156…

When I looked back the data, I wondered why only P. distasonis increased in Acr-treated mice, but not P. goldsteinii? Investing the difference of the ability to utilize carbohydrates in detail may be an interesting way to modulate the gut microbiota by diet🤔

4/n. (Fig. 3) Acarbose suppressed anaphylaxis depending on gut microbiota alteration. We found that Parabacteroides distasonis dramatically increased in acarbose-treated mice, and a combination of acarbose and P. distasonis also suppressed anaphylaxis.

@wenzhang1120 @NatureMicrobiol Thank you! Also, congratulations for starting your own lab!!✨Very exciting!

@KyosukeYakabe @NatureMicrobiol Congratulations!🎉

Excited to share that I will be starting my independent lab at @Rutgers_NJMS @RutgersU this summer! The Zhang Lab will study Sensory Neuroimmunology - how the sensory nervous system regulates immunity, inflammation, and host-microbiota interactions at mucosal barriers.

8/9. Correction: ‘have less experienced’

9/9. I truly appreciate all collaborators. We could not complete this study without their fantastic collaboration. I understand that this study still includes some unrevealed points. However, our study will highlight a new insight into drug repositioning.

Acarbose redirects gut microbiome utilization of dietary carbohydrates to suppress anaphylaxis in mice dlvr.it/TSW5lF #MicroSky

Nature research paper: Transposable elements are driving rapid adaptation of Enterococcus faecium go.nature.com/42qOQKc

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命の始まりは父母ゲノムの「別居」から －父母ゲノム間の競合が受精卵の発生を助ける－ doi: doi.org/10.1038/s41586… 詳細はこちらをご覧ください⬇️ riken.jp/press/2026/202… #理研プレス

Nature research paper: Early fibrotic niches establish tumour-permissive microenvironments go.nature.com/4eyjatK