LLicit

@Diet0Nutrition Sugar, Cancer, and the Comfort of a Simple Villain drsimpson.com/p/sugar-cancer…

In 1924, Otto Warburg proved that cancer cells thrive via anaerobic fermentation of glucose, yet modern oncology completely ignores nutritional mitigation during treatment.

@LiveAncestral Beating the Odds: Inside the Tribe with a Near-Zero Rate of Heart Disease 70% of their diet is carbohydrate, 14% protein, 14% fat Lowest heart disease rates ever recorded Low blood pressure Low dementia rates Low obesity Low abnormal glycemic control paddybarrett.substack.com/p/beating-the-…

There is no such thing as an essential carbohydrate. That is not an opinion. That is basic biochemistry. There are essential fats. There are essential proteins. Your body cannot make them, so you need to get them from food. Carbohydrate is not on that list, because your liver can make the glucose you need from fat and protein. That process is called gluconeogenesis. So why were people told to base meals around grains? The 1977 dietary guidelines pushed 6 to 11 servings a day. That was presented as health advice. It also happened to suit a food system built around cheap, storable, profitable products. A population living on meat, eggs, and simple whole food is harder to sell to on repeat. That is worth thinking about. When I cut back on carbohydrates my energy stabilised, my hunger became manageable, and I stopped thinking about food every two hours. That is not what you would expect if you had removed something essential. Your body does not need carbohydrate. It needs enough energy, enough protein, enough fat, and the right signals. What is the most difficult carb for you to give up?

@LiveAncestral Four common dietary factors in longevity diets 🍎 More fruit ⬅️ 🍆 More vegetables 🌾 More wholegrains ⬅️ 🫘 More nuts and beans Note meat going the other way in the table below Diet Patterns and Mortality: Common Threads and Consistent Results jn.nutrition.org/article/S0022-…

@LiveAncestral Kind of ridiculous logic Exercise is non-essential also - but very beneficial

@Diet0Nutrition Rabbits also have a stomach pH of 1 to 2 open.lib.umn.edu/bunnybellies/c…

I keep seeing people claim humans are “plant-based by design.” But then you look at anatomy: Human stomach pH ≈ 1.5–3 (high acidity for protein breakdown and pathogen defense) Shorter colon than herbivores Small fermentation capacity compared to ruminants Herbivores are built for bulk plant processing. Humans are not structured like that. We sit metabolically in a very different category.

@SamaHoole From your suggestions, it sounds like you would struggle to get off the floor eating kale Quite odd then that eating a PBD has so many benefits??? I'll grant you that a carnivore table would look pretty much the same (just with all the little insignificant arrows going up)

Kale. Superfood. The leafy green so morally superior that the supermarket has built an entire chiller cabinet around it. The smoothie ingredient your colleague mentions twice a meeting. The garnish that earned a New York Times trend piece, a Beyoncé t-shirt, and its own day on the calendar. Let's have a look at what you actually bought. Kale is a brassica. Brassicas come loaded with goitrogens, compounds that interfere with iodine uptake and can suppress thyroid function in people who eat them regularly, especially raw, especially in smoothie quantities. The thyroid is the small organ that runs your metabolism, your temperature, your energy, and your mood. The wellness influencer in the kale smoothie advert is not telling you any of this. It contains a moderate dose of oxalates. Not the worst on the green spectrum, but enough that the daily-kale-smoothie crowd are quietly assembling kidney stones over months and wondering where the back pain came from. The fibre content the marketing leans so heavily on is insoluble plant matter that the human gut cannot meaningfully digest. It scours the intestinal lining on the way through. Some people tolerate it. Many don't, and discover this only after years of "doing everything right." The iron is non-haem and poorly absorbed. The calcium is bound by the same oxalates that built the kidney stone. The vitamin K is real, but you'd get more from a couple of yolks and absorb it twice as well alongside the fat. Then, having eaten the kale, you spend the afternoon bloated, slightly chilly, slightly anxious, and faintly proud. Three eggs and a piece of grass fed butter would have done the job in eight minutes for less money, with no oxalates, no goitrogens, and no need to talk about it in the office.

@SamaHoole ANDI scores measure an extensive range of micro-nutrients, including vitamins, minerals, phytochemicals and antioxidant capacities Kale scores 50X higher than beef & 37X higher than eggs

@rob22184 @je2har @SamaHoole Yet smoking was shown to be harmful via epidemiological studies. Below might be more to your taste Both processed and unprocessed meat directly linked to the exact type of mutations found in colorectal cancers aacrjournals.org/cancerdiscover…

@LLicit_Tweet @je2har @SamaHoole This study suffered three limitations of all epidemiological studies: association, not causation; relative, not absolute risk; and the healthy person confounder (the UNhealthy person confounder in this case – burger ‘monsters’ tend to be less healthy overall).

WHO: bacon is Group 2A. Possibly carcinogenic. Citizen: what else is in that group. WHO: hot beverages above 65 degrees. Citizen: tea? WHO: yes. Citizen: so my morning cup of tea and my breakfast bacon are in the same cancer category. WHO: technically yes but the public should focus on the bacon. Citizen: why. WHO: we cannot say. Citizen: who funds you. WHO: we cannot say. Citizen: I'm going to have a bacon sandwich and a cup of tea and you can have a quiet sit down.

@markkaplan20 This post highlights a study with a modern effective statin in primary prevention Cardiovascular death, MI, or ischemic stroke was reduced by 25%. All cause mortality also ⬇️ Plus no significant differences in adverse events over the 5 years dralo.net/blog/repatha

Imagine you invented a product. It worked for 1 out of every 200 people who used it. The other 199 got side effects and zero benefit. In any other industry, that product would never see the light of day. It would be a catastrophic failure. An embarrassment. Instead it became the best selling drug in the history of medicine. Taken by 250 million people worldwide. Think about how much lying, corruption, and brainwashing had to happen for that to be possible. That is the statin story. And it is finally unraveling. 🧵

@markkaplan20 That's in a primary prevention setting (as your graphic makes clear), but would more impactful in secondary prevention Additionally the study cited is quite old - their are more effective statins available now doi.org/10.1016/S0140-…

@SamaHoole The same sort of thing is very common at the other end of the spectrum (ie carnivore) Spend 10 minutes looking through all the problems reported by many people on Carnivore Cringe instagram.com/carnivorecring…

Every former vegan who left the diet for health reasons describes the same moment. Anne Hathaway: "I had a piece of salmon and my brain felt like a computer rebooting." Miley Cyrus: "I had to introduce fish and omegas back into my life because my brain wasn't functioning properly. Now I'm so much sharper. I was running on empty." Tim Shieff, after 8 years vegan: "My depression lifted, joints feeling a lot better, energy back in my body." Mikhaila Peterson, after a lifetime of autoimmune illness: "All of my symptoms went into remission. I've never felt like this before." Kai-Lee Worsley, whose hair was falling out in chunks: "As soon as I took a couple of bites I felt better. It has literally saved my life." Sharper. Lighter. Awake. Rebooted. Lights back on. Nobody who quit beef for veganism describes their first lentil bowl this way. The body keeps a record. The body has the final say.

@SamaHoole Are Supercentenarian Claims Based on Age Exaggeration? Spoiler alert - no bluezones.com/news/are-super…

Blue Zones, summarised: Researcher: "We found 50 centenarians in this mountain village! They eat mostly plants!" Local official: "Actually we have a pension fraud problem. Many of those people aren't that old. Some are dead." Researcher: "We're not including that in the documentary." Local butcher: "Also we eat a lot of lamb and cheese here." Researcher: "We filmed someone holding a tomato. That's the angle." Centenarian: "I've eaten pork fat every day for 92 years. My father did the same. He lived to 96." Researcher: "Can you hold this bowl of lentils for the camera?" Centenarian: "But I don't eat lentils." Researcher: "Just hold it. Look wise. Say something about beans." Centenarian: "..." Researcher: "Perfect." Netflix viewers: "Wow. Lentils are the secret to longevity."

@SamaHoole The powerful thing about Blue Zones is that the initial impetus was to find the longest living populations. Only after finding these 5 (now 6) Blue Zones, did they discover a commonality in their diets. Namely unprocessed & largely (90-95% plant based) Pretty telling ...

@SamaHoole Both of Saul Newman's papers on this topic are at the preprint stage (ie not peer reviewed or officially published) One of them has been at this stage since 2019. That is 7 years and counting ... erictopol.substack.com/p/a-look-into-…

@DrKristieLeong @dr_ericberg This video discusses a study where resistant starch (40g/day)> 50% reduction in liver fat youtube.com/watch?v=jII_ID…

I reduce the effective carb content of potatoes and pasta by placing it in the fridge for 12 hours after cooking it. Cooling increases resistant starch, which has an anti-inflammatory effect on the gut lining and also acts as a prebiotic. Plus, conversion to resistant starch reduces the effective carb content, so it's easier on your blood sugar.

What's one healthy swap that made your meals better? Dr. Eric Berg, DC, not MD; information only

@tonyricciardix @evernote @bendingspoons Think they are aiming a people who use it extensively and appreciate all the features That includes me and quite happy to pay the $5/week as I get lots of value out of it

@evernote @evernote @bendingspoons just doesn't get it. It's why they're losing so many users and mindshare to apps like Obsidian. When your entire business model is based on squeezing as much $ out of your users as possible, you're going to lose.

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@SamaHoole Alternatively - an avocado with a little salt, pepper & lemon juice

Vegan cheese, ingredients in approximate order: - Refined coconut oil - Modified potato starch - Modified maize starch - Salt - Olive oil extract for colour - Carrageenan - Calcium phosphate - Yeast extract - Lactic acid (vegan-derived, they specify) - Natural flavouring (whatever that means) - Vitamin B12 Actual cheese, ingredients: - Milk - Salt - Rennet - Bacterial cultures Four ingredients, all of which a small child could identify, versus eleven, several of which have never appeared in any kitchen prior to 1995. The cheese was made by a man in Somerset using methods his grandfather taught him. The vegan cheese was assembled in a factory in Holland by an extruder. You paid more for the second one because the marketing said it was kinder.

@je2har @rob22184 @SamaHoole I did provide a link to the paper so you can look at that But another line of evidence if you like Both processed and unprocessed meat directly linked to the exact type of mutations found in colorectal cancers

@rob22184 @LLicit_Tweet @SamaHoole Prove it

@CaryKelly11 And who is conducting this radical re-evaluation? Must be cardiologists, epidemiologists, physiologists etc No - a psychiatrist and someone selling supplements

The latest re-evaluation of the cholesterol hypothesis suggests that because of corporate influence, we've become obsessed with LDL-C while stronger variables deserve more attention. Real driver? According to the review, ApoB particle burden triggered by oxidative stress and inflammation from excess refined sugar, not saturated fat or steak. Seed oils also need more scrutiny. What does this mean? It means be on the lookout for chronic inflammation. Achy joints and bones are the smoke and heart disease is the fire.

@CaryKelly11 And what increases ApoB particle burden? Saturated fat