@theHumanBorch Congrats! beautiful work and lots of inspiration. I am also jealous of that orca-shaped UMAP in Fig1! My 4-yo would be so proud of me if I brought that back from work ^^
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Liliana Elisa Lucca
267 posts
Liliana Elisa Lucca
@LaLilli11
"Yeah Mr White. Yeah, science!" Immunologist at CRCT (FR) and Yale (USA). Cancer immunology, T cell receptor, R Mother of one, couch gymnast, low-key runner.
Toulouse, France Katılım Mart 2017
216 Takip Edilen86 Takipçiler
@ChelseaParlett when are they ever going to incorporate the "did you mean..?" warning? They already sort of do it with = instead of ==
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At this point, if dplyr can’t understand what I mean by
|> muate()
that feels like a skill issue on dplyr’s end💅
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You know how grants have very precise deadlines, like Feb 28th by 5pm Eastern? Imagine, just imagine if those agencies imposed the same rigour to themselves, instead of saying "results will be out in the month of July".
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@OdedRechavi Me today! Currently procrastinating said writing
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Only reason why the met Gala should continue to exist
Jorge Zárate, MD@jzaraterod
Alright, by popular request from like one person and to amuse basically just myself… here’s #MetGala 2024 outfits as medical specialties for a third year in a row
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USB ports are to computers what pockets are to women's clothes. Why can't we have them? No, I don't want to buy an expensive adapter so that I can stick a USB drive in my laptop. I've spent that money to buy a purse to carry all the things that I can't fit in my pocketless outfit
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Tried #ChatGPT for coding in spite of me (I lazily asked for suggestion on our lab chat and a student fwd me a chatGPT response). Mesmerized at the straight face with which it just made up a non-existing function.
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@science_dot @maw_tweets If only they would pay at least some decent proof reading and formatting! There is literally only cash flowing into these journals, no cash flowing out. Amazing business model.
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Nature now charges $12,290 US to publish a single article open access. Shall we list some things that cost less than that? I'll go first: a 2017 BMW 330i sedan, a 7-day cruise for a family of four, six Louis Vuitton purses. 🤪
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@maw_tweets @igordownunder For example, 6-7 vials of fluorescent antibodies, each enough to stain 100 samples.
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@igordownunder Depends how you look at. What you pay out of your grant/budget is a choice. The money could go to something else.
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That feeling when you paste all the text from the pre-application into the full application form and 8 out of 20 pages are already filled #grantseason #humanwriting
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am running (someone else's) plink command that has the following sequence of arguments:
--allow-no-sex --make-bed
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Very exciting and it goes back to splicing!
Itai Yanai@ItaiYanai
How did we lose our tail? A simple question.. but it wasn't really asked before! We discovered a plausible scenario for the genetic mechanism that led to tail loss. Amazing that such a big change may have been caused by such a small genetic event. nature.com/articles/s4158… @BoXia7
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@NinaSteele17 @Momademia Mine was born in April 2020 and we really only had two bad winters, 2020/21 and 2021/2022. She must have missed 3-4 days of school since summer 2022! But we live in France where people have a platinum-iridium microbiome..
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There has actually not been a single week in which myself or my toddler has not been ill since she started daycare in December. I’m exhausted by this, and talking to parents of older kids it honestly doesn’t seem that much better?! @Momademia
Royal Oak, MI 🇺🇸 English
@N_Fazilleau What happened to "it was a shame that France was absent from the race to the COVID vaccine, we need to invest more?"
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‘Incomprehensible’: scientists in France decry €900-million cut to research nature.com/articles/d4158…
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@moeinminn I once got charged 370$ for a couch that was listed at 730$!
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Tell me about your worst work mistakes. Sometimes I comfort myself with not being the person who got a ship stuck in the Suez Canal but that's not working today.
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@eofallthings Accidentally turned off the freezer counter at an ice cream parlor where I was working when I was 20. All the ice creams melted (this was in Italy where ice cream is a year-round basic human right).
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I am having a bad Friday, but luckily twitter delivered.
Will Owens@willovvens
heard UMAP was popular on twitter, anyone have any advice on how to tighten up the clusters?
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@angie_rasmussen @mbeisen @eLife More editorial discretion, or I should say, less editorial washing their hands clean of any responsibilities, like they do in traditional journals, sounds like a dreamboat to this author.
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@mbeisen @eLife Am I wrong in understanding the eLife publication model: that papers are accepted for publication prior to review based on editorial discretion? My analysis was based on you saying that’s exactly what you did:
Michael 英泉 Eisen@mbeisen
@HL3133 @Bryce_Nickels @eLife (Mind you it was me who tried to get this paper into eLife - without me it had no advocates)
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This is just completely false. Either @angie_rasmussen doesn’t understand the new @eLife model she is mocking, or she’s lying about what happened. At no point did I “accept” the paper - as there is no acceptance in the new model. I sent it out for public review.
Dr. Angela Rasmussen@angie_rasmussen
From the exchange above, we see that Michael Eisen, the then-EIC of eLife, championed this paper and accepted it over the objections of subject matter experts just because he decided he thought it should. Except that went…poorly. eLife ended up rejecting the paper after all.
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@mbeisen @AllofUsResearch @Nature The tenet of racism is that biology justifies supremacy of white people. Surely we can deny this hierarchy without denying human diversity (that any PCA plot will also show, although more meaningfully)? Feminism doesn't require denying biological differences between genders.
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This paper from @AllofUsResearch needs to be retracted by @nature immediately. Under pretext of inclusivity it features a scientifically invalid representation of genetic diversity and race that is going to feature in racist literature for decades. nature.com/articles/s4158…
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@lpachter Guilty of using UMAPs in cancer papers (even if I dislike them), but most people don't discuss distance between clusters at all in the actual paper. It's mostly a colourful intro to some more solid data exploration. Can anyone cite an example of a point made about a UMAP alone?
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For the record I am aware of only one setting where it is appropriate to use UMAP: art.
UMAP is misleading and potentially harmful not only in population genetics. When it serves as Fig. 1 in papers on life-and-death matters, e.g. cancer studies, it can also do real harm.
Jonathan Pritchard@jkpritch
For the record, I'm not a UMAP hater in all settings, but I think it's misleading and potentially harmful for this specific problem.
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