Chao Li Lab

56 posts

Chao Li Lab

Chao Li Lab

@LabChao

Beijing, China Katılım Kasım 2018
295 Takip Edilen702 Takipçiler
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Chao Li Lab
Chao Li Lab@LabChao·
Our latest work shows how modern total synthesis can enable therapeutically meaningful discovery, uncovering selective anti-C. difficile activity and toxin-protective effects of structurally complex polyether ionophores. Now available on ChemRxiv: chemrxiv.org/doi/full/10.26…
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Chao Li Lab
Chao Li Lab@LabChao·
One step. Two C–C bonds. Three natural product syntheses. Our auto-tandem catalytic cascade for natural product synthesis is out today in JACS!pubs.acs.org/doi/10.1021/ja…
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Chao Li Lab
Chao Li Lab@LabChao·
Our Chem. Soc. Rev. Article! Radical Retrosynthesis: A Powerful Strategy for Modern Assembly of Terpenoid Natural Products. Modern radical chemistry—MHAT, RAE, XEC, photoredox, HAT—reshapes retrosynthetic logic for complex terpenoids. pubs.rsc.org/en/content/art…
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Chao Li Lab
Chao Li Lab@LabChao·
Thrilled to share our progress on the synthesis of highly oxidized DMOA-derived meroterpenoids—now out in JACS:pubs.acs.org/doi/10.1021/ja…! The unexpected reaction we stumbled upon in the final step turned out to be especially fascinating.
Total Synthesis@TotalSynthesis

#TotalSynthesis of DMOA-Derived Meroterpenoids: Achieving Selectivity in the Synthesis of (+)-Berkeleyacetal D and (+)-Peniciacetal I by Jianpeng Zhang, Xiaotong Luo, Jingfu Zhang, and Chao Li @LabChao in @J_A_C_S pubs.acs.org/doi/10.1021/ja…

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Shiqiang Ma
Shiqiang Ma@ma_shiqiang·
@LabChao Congratulations! Very nice work. It must take a very long way to this success!
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Chao Li Lab
Chao Li Lab@LabChao·
We're excited to have achieved a structure-activity relationship analysis of the complex natural antibiotics Kibdelomycin/Amycolamicin through total synthesis. We hope this work will contribute to the development of new antibiotic therapies. onlinelibrary.wiley.com/doi/10.1002/an…
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Yandong Zhang
Yandong Zhang@YandongZhang16·
Excited to share our latest paper on the total synthesis of Illicium sesquiterpenes. Not only access more targets but synthetically connect distinct molecular architectures of different subfamilies through late-stage skeletal reorganization triggered by Lewis acids or oxidants.
J. Am. Chem. Soc.@J_A_C_S

Divergent Total Syntheses of Illicium Sesquiterpenes through Late-Stage Skeletal Reorganization | Journal of the American Chemical Society @CHNSci @TotalSynthesis @TotalSyntheses #Divergent #TotalSynthesis #sesquiterpenes #Rearrangement #LateStage pubs.acs.org/doi/10.1021/ja…

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