Maillard Lab

We have postdoc positions at the The Institute for Soft Matter Synthesis and Metrology to work closely with scientists at @Georgetown and NIST on soft matter, broadly defined, including single molecule biophysics. Apply here academicjobsonline.org/ajo/jobs/28886 by November 7!

Come to work with us! The Institute for Soft Matter Synthesis and Metrology @Georgetown is looking for Post-Doctoral Research Fellows to work closely with scientists at Georgetown and NIST on soft matter, broadly defined. Apply here academicjobsonline.org/ajo/jobs/28886 by November 7!

New paper alert! We used optical tweezers to resolve heterogenous folding/unfolding pathways of repeat expanded huntingtin mRNA, revealing how hairpin slippage can seed inter-strand base pairing and promote aggregation. Congrats @NothinBut_Brett! 👏👏 nature.com/articles/s4146…

BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”

@agzestos @GUChemistry Thanks for invitation, Alex. It was a real pleasure to give the seminar and meet AU students.

Many thanks to Prof. Rodrigo Maillard @LabMaillard @GUChemistry for a great seminar on using single molecule methods to study allostery in protein kinases at our seminar series.

Starting the semester strong with a hike with my graduate students at Great Falls, VA! It doesn't hurt, also, that BSF (@usisraelbsf) is funding our project on PKA RIbeta in collaboration with the Ilouz lab @RIlouz

@RIlouz We are also thrilled that we are moving forward with this exciting project with the support of BSF!

Incredibly honored to receive the BSF grant. Thrilled to collaborate with @LabMaillard on a new neurodegenerative disease we’ve name NLPD-PKA. We're looking for a talented PhD student to join our team. Interested? Reach out!

Congratulations to Dr. Ronit Ilouz from our Faculty for winning a research grant from the U.S.-Israel Binational Science Foundation (BSF). The laboratory led by Dr. Ronit Ilouz investigates mechanisms for the formation of a unique inherited neurodegenerative disease, and gave it the name: NLPD-PKA. The disease develops in patients with a specific genetic mutation in the protein, which leads to the formation of protein clusters in the brain, similar to other neurodegenerative diseases such as Alzheimer's and Parkinson's. The grant is in collaboration with Dr. Rodrigo Maillard from Georgetown University in the USA. The two laboratories will combine knowledge and focus on the cellular and molecular effects of the mutation on the brain, while discovering the mechanisms leading to the disease, with the aim of developing innovative and useful solutions, offering a tremendous advantage in promoting promising and applied research directions. @RIlouz @Bar_ilan

Save the date for Single Molecule Biophysics 2025 (SMB 2025) to be held over January 5-10, 2025 (inclusive) at the Aspen Center for Physics, Aspen, Colorado. To get your name on our emailing list, contact tperkins@colorado.edu. Please RT. jila.colorado.edu/smb/

@RIlouz @Brain1878 @ubarilan @GondaBrain @biumedicine @UIowaNeuro Congrats to Ronit and all the team!

🔥Incredibly proud to share our paper @Brain1878 🥳 academic.oup.com/brain/advance-… @ubarilan @GondaBrain @biumedicine @UIowaNeuro #brain #neurodegenerative diseases #rare diseases 1/5 Follow&Retweet!!

Congratulations to Christian for being selected for induction as a Fellow in the National Academy of Inventors (NAI). See: otc.georgetown.edu/news/celebrati…

@dixitvishva Super cool, and be careful!

Visiting a friend in Cape Town!

A few years old, but worth a read (perhaps in particular to those who do ML in BIO or take biological databases for granted) "How Margaret Dayhoff Brought Modern Computing to Biology" smithsonianmag.com/science-nature…

Jeff Urbach named Vice Provost for Research college.georgetown.edu/news-story/urb…

@ZhanglabY @BerroLab Beautiful work, Yongli and co-authors. Congrats!

Our article on in vivo force sensors appeared in Science Advances. Thank Yuan Ren, Julien Berro @BerroLab, and Jie Yang! Force redistribution in clathrin-mediated endocytosis revealed by coiled-coil force sensors | Science Advances science.org/doi/full/10.11…

@GalburtLab @thedrakejensen @NAR_Open Congrats Eric, and to the team!

Our new manuscript born of work led by lab members @thedrakejensen and Ana Ruiz Manzano is now available @NAR_Open. It describes a fluorescent-aptamer-based transcription assay for parallel steady state rate measurements: doi.org/10.1093/nar/gk…

@ASCBiology Congrats @BoyceLab and to all new 2023 ASCB Fellows!

Meet the 19 distinguished scientists recognized as 2023 ASCB Fellows! ascb.org/society-news/n…

@rubenlgonzalez @RuedaLab @ckinzthompson Thanks Ruben and @mary_munson4 for the invitation. It was a fantastic meeting with great people and friends!

Thanks to Jane Dyson, @LabMaillard, and @RuedaLab, as well as @ckinzthompson and all the other contributing speakers for an AMAZING Proteins in Motion session on Day 3 of #PS37!