Saghatelyan Lab

Happy to share our article in @NeuroCellPress We show how cilia beating of ependymal cells lining the walls of brain ventricles regulate neural stem cells activation/quiescence. This work was made possible by an amazing work of trainees in the lab and wonderful collaborators 1/7

@SChenlab Thanks Simon!

@Lab_Saghatelyan congrats Armen!!!

Happy to share our article in @NeuroCellPress We show how cilia beating of ependymal cells lining the walls of brain ventricles regulate neural stem cells activation/quiescence. This work was made possible by an amazing work of trainees in the lab and wonderful collaborators 1/7

@LisaJ456 @NeuroCellPress Thanks Lisa!

@Lab_Saghatelyan @NeuroCellPress It’s so nice to see this beautiful work now published! Hearty congrats Armen to you and the team 🎉

New paper from the lab. Using longitudinal ca imaging, activity-dependent tagging and optogenetics, we show that newly allocated fear engram neurons in amygdala undergo a brief period of coordinated “offline reverberation” immediately after learning. pnas.org/doi/10.1073/pn…

@neur1s @NeuroCellPress Thank you Sofiya!

@Lab_Saghatelyan @NeuroCellPress Great news, congratulations!

@karunsinghneuro @NeuroCellPress Thanks Karun!

@Lab_Saghatelyan @NeuroCellPress Beautiful work Armen.. many congrats to the team!!!

Many questions remain unanswered for EC-NSCs mechanical interactome and whether similar mechanisms are at play in other somatic stem cells that are also surrounded by ciliated epithelial cells. Huge thanks to the reviewers for their very insightful comments and @NeuroCellPress

This work reveals an intricate interplay between ECs and NSCs through mechanical forces and highlights some of factors/mechanisms that may lead to generation of these mechanical forces. 6/7

@Masha_P_K @MakashovaOlena @LaporteCeleste @Chris_QChen @osmoland @AKhoutorsky @mcgillu @McGillMed Huge congrats Masha!

Thrilled to share our new study showing microglia prune astrocyte processes to regulate synaptic transmission, neuronal activity, and salt-induced hypertension in🐀. Huge team effort! @MakashovaOlena @LaporteCeleste @Chris_QChen @osmoland @AKhoutorsky @mcgillu @McGillMed

@vbprovencher Bravo Vincent!

First preprint from the lab: biorxiv.org/content/10.110…

@Franklandlab Huge congrats Paul!

Sharing a new paper from the lab. This paper, led by Sangyoon Ko, represents a merging of two longstanding research themes in the lab-- adult neurogenesis and systems consolidation. rdcu.be/el18q A short thread follows for those interested

Come to our 7th Satellite meeting (Stem Cells, Brain Development and Regeneration) in Toronto, May 21st 2025! Great line up of speakers including trainee talks. Great place to network and showcase your work! Spots still available.

@AKhoutorsky @Weihua1990 @AmirMinerbi @GonzalezEmBio @King_Lab_McGill Congrats Arkady!

Excited to share our latest research, led by @Weihua1990, in collaboration with @AmirMinerbi, @GonzalezEmBio, @King_Lab_McGill and many others. The gut microbiota promotes pain in fibromyalgia: Neuron cell.com/neuron/fulltex…

@NeuroNaud @JCBeique @grossmancooper @efharkin_ Huge congrats Richard, @JCBeique and the team!

What are serotonin neurons trying to tell the brain? Our work on the question has been so much fun (@JCBeique , @JermiahYCohen, @grossmancooper ). Check out @efharkin_ 's exciting paper biorxiv.org/content/10.110… nature.com/articles/s4158…

@antoinedechevig Thanks a lot Antoine! Hope all is well!

@Lab_Saghatelyan That is an amazing tour-de-force and very insightful results, congrats Armen and team 🥳

Thrilled to share our work on how neural stem cells (NSCs) interact with distinct cell types in their niche. We use Ca2+ imaging in NSC processes and post-hoc iterative immunolabeling for multiple cell types to link NSCs functional activity to niche cell types inducing it. 1/8

Don’t miss our satellite meeting on Stem Cells, Brain Development and Regeneration at @CAN_ACN . Stellar line-up of speakers, several slots for trainees talks! The program and registrations at Stem Cells, Brain Development and Regeneration – Canadian Association for Neuroscience