colm leonard

104 posts

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colm leonard

colm leonard

@LeonardColm

NHS Consultant Chest Physician; Honorary Professor of Respiratory Medicine; Chief Clinical Officer INFEX Therapeutics: AMR & sustainable antimicrobial pipeline

United Kingdom Katılım Temmuz 2019
746 Takip Edilen292 Takipçiler
INFEX Therapeutics
INFEX Therapeutics@INFEX_TX·
A great day attending #BioInfect 2026 at @AlderleyPark ! Infex's Chief Clinical Officer, Colm Leonard, delivered an update on our flagship RESP-X program, a Phase 2a monoclonal antibody to treat non-cystic fibrosis bronchiectasis (NCFB).
INFEX Therapeutics tweet mediaINFEX Therapeutics tweet media
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colm leonard
colm leonard@LeonardColm·
@Bionow @INFEX_TX Thanks for the introduction. Slight typo. I was clinical lead for UK antimicrobial subscription project, which delivered a world first ‘pull incentive’ for 2 antibiotics, until I jumped into antimicrobial development role with INFEX in 2023
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colm leonard
colm leonard@LeonardColm·
@OSibila It is indeed a nice review article, Oriol. However, it is incomplete as it excludes RESP-X, a very long-acting monoclonal antibody targeting Pseudomonas aeruginosa. Phase 1 healthy volunteer data presented at Vienna ERS, phase 2a study just finishing with data imminent @INFEX_TX
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Oriol Sibila
Oriol Sibila@OSibila·
This ERJ Advances article summarises the developments in the past decade in the rapidly advancing field of emerging therapies in bronchiectasis bit.ly/4oW8qYi
Oriol Sibila tweet media
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colm leonard
colm leonard@LeonardColm·
@dublin_damo Please do keep posting Damian. I left Dublin a long time ago & then photos & posts are very enjoyable, likewise those from overseas. Some great ideas for travel & food 🍱
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Damian
Damian@dublin_damo·
I can put up with all the dickheads because most people on here are like this, sound, kind, decent, and if people enjoy the posts, I'll keep doing them, costs me nothing!
Ron@lester_durden

@dublin_damo Enjoy!! Have a great Christmas & New Year - really enjoy your posts, keeps an Irish man in Wales in touch with the auld sod

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colm leonard
colm leonard@LeonardColm·
Be wary of using @FedEx for deliveries from USA to UK. My new stethoscope arrived in UK one week ago & I still have not received it. FedEx live chat & phone numbers do not allow human conversation! Appalling service
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colm leonard
colm leonard@LeonardColm·
@FlyLoganair You didn’t read my message. The handling agent doesn’t answer the phone & by email they say to contact Loganair!
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Loganair
Loganair@FlyLoganair·
@LeonardColm Hello Leonard. I am sorry to hear of this experience. We would advise your partner to contact our handling agents in Aberdeen for any updates. Thank you. ^mw
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colm leonard
colm leonard@LeonardColm·
Beware flying with @FlyLoganair as my Wife experiencing terrible customer service Manchester to Aberdeen . Flew yesterday to Aberdeen, no baggage put on plane, told it would be on following flight, 2 flights later bag still in Manchester. Loganair unhelpful as is handling agent
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colm leonard
colm leonard@LeonardColm·
@Mike_kim714 I’ve enjoyed your insights into life on tour Michael. Wishing you even more success for rest of year & next season
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Michael S. Kim
Michael S. Kim@Mike_kim714·
Giving away my Titleist staff bag that I used from the Open Champ to the BMW I believe. Must be a follower Comment, like, retweet for a chance to win!
Michael S. Kim tweet media
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colm leonard
colm leonard@LeonardColm·
@dublin_damo Thanks so much for posting this journey, Damian. It has made me determined to do one of the Camino walks in the not too distant future
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Damian
Damian@dublin_damo·
Is it too early for an Estrella Galicia? No sir, it is not.
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Damian
Damian@dublin_damo·
And here we are, the end of 5 very enjoyable days on the Camino Inglés. Many thanks for all the nice feedback and supportive messages along the way, I really do appreciate them.
Damian tweet media
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colm leonard
colm leonard@LeonardColm·
Very excited to work with Asian ADVANCE-ID network to plan clinical trials of our novel metallo-beta-lactamase (MBL) inhibitor, MET-X. Antimicrobials targeting MBL mechanism of Gram negative bacterial resistance to antibiotics is key gap in pipeline. @davidantibiotic @INFEX_TX
INFEX Therapeutics@INFEX_TX

Infex agrees collaboration with Asian clinical trials network, ADVANCE-ID Memorandum of Understanding signed to investigate hospital-acquired drug-resistant infections in Asia: infextx.com/infex-agrees-c…

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colm leonard@LeonardColm·
Excited to share our licensing deal in India for clinical development of MET-X our novel metallobetalactamase (MBL) inhibitor. MBL mechanism of resistance is an enormous problem in India & SE Asia & a rising problem EU & USA. MBL mechanism is a key pipeline priority for WHO
INFEX Therapeutics@INFEX_TX

Infex signs exclusive license agreement with Venus Remedies Ltd to advance MET-X through clinical development and commercialisation in India: infextx.com/infex-signs-ex…

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colm leonard
colm leonard@LeonardColm·
@INFEX_TX Excited to share our licensing deal in India for clinical development of MET-X our novel metallobetalactamase (MBL) inhibitor. MBL mechanism of resistance is an enormous problem in India & SE Asia & a rising problem EU & USA. MBL mechanism is a key pipeline priority for WHO
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colm leonard
colm leonard@LeonardColm·
@gardp_amr thanks for sharing @UKHSA reportThe doubling of reporting rates for carbapenemase-producing bugs from 4.7/100k to 10.1/100k between 2021 & 2023 is scary. One health approach, optimal stewardship of existing antibiotics & a robust pipeline of new agents urgently needed
Global Antibiotic R&D Partnership (GARDP)@gardp_amr

📊 New data from @UKHSA: Antibiotic-resistant infections in 2023 exceeded pre-pandemic levels An alarming 66,730 serious cases were reported - compared to 62,314 in 2019. 👉gov.uk/government/new…

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colm leonard
colm leonard@LeonardColm·
This is scary, warzone superbugs come to visit! Funders, regulators, HTA entities need to facilitate antibiotic pipeline to have necessary armoury to fight this threat. Antimicrobial resistance is not a silent threat. Antimicrobial BioTech needs support harvardpublichealth.org/global-health/…
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NICE
NICE@NICEComms·
📢New UK-wide asthma guideline launched Developed by @BTSrespiratory, NICE and @signguidelines it revolutionises asthma diagnosis and treatment by recommending combination treatments instead of ‘reliever-only’ inhalers for newly diagnosed cases. 🔗nice.org.uk/news/articles/…
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colm leonard
colm leonard@LeonardColm·
@WeFightAMR @AmrInsights This situation cannot continue. We need the PASTEUR Act ASAP. Otherwise we face a future at the mercy of antibiotic resistant infections without an adequate armoury of effective agents
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Working to Fight AMR
Working to Fight AMR@WeFightAMR·
Since 2013, the FDA has approved 10 new antimicrobials from small companies. Since then, nearly every company behind those antimicrobials has filed for bankruptcy, was acquired, or is shutting down. #WAAW #USAAW24
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Colin S Brown
Colin S Brown@colinbrown_id·
Delighted to announce that the University of Oxford are the recipients of £11M for the upcoming Health Protection Research Unit in Healthcare Associated Infections and AMR, directed by @stat_sarah and which I will co-lead - very exciting research ahead! nihr.ac.uk/news/ps80-mill…
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