Yuanyue Li

Data from the West Coast Metabolomics Center at UC Davis are now in #PubChem. Check it out: ow.ly/TIBY50Tb7S4

1st year PhD student showing up at the 8 am panel with 25 expertly crafted slides, 57 backup slides, and print-outs prepared four weeks in advance vs Tenured professor giving the keynote with two slides of mood pictures clicked together in the hotel lobby 15 minutes earlier

Exciting final day at the @asmsnews Asilomar Conf on Computational Mass Spec meeting. @The_AnderPLANTS (Chris Anderton) is wrapping up the early morning session now. We took time on Saturday morning to take a group photo. The future is bright for Computational #TeamMassSpec

@TaoThuan @WCMC_UCDavis Thanks!

@LiYuanyue @WCMC_UCDavis Excellent work, Yuanyue!

We have developed a method called Flash entropy search for calculating MS/MS entropy similarity at lightning speed. It can perform an open search on ~1 billion spectra in just 2 seconds! It also support neutral loss search and hybrid search. @WCMC_UCDavis doi.org/10.1038/s41592…

Flash entropy is a fast mass spectral similarity search method for metabolomics data that speeds open search, hybrid search and neutral loss search up to 10,000 fold. @WCMC_UCDavis @LiYuanyue nature.com/articles/s4159…

A fantastic invention by Dari Shalon and leading experts in #microbiome research, #proteomics and #metabolomics produced a great inside of "Profiling the human intestinal environment under physiological conditions" published in @Nature today. nature.com/articles/s4158… @metabinfo

Hot out of the press: we have today two NATURE papers. We are very thrilled @NatMetabolism is our paper "Human metabolome variation along the upper intestinal tract". nature.com/articles/s4225…. #exposome #metabolomics Check the next tweet for the second paper.

Yuanyue Li of the Oliver Fiehn lab discusses the concept of spectral entropy and how it improves the analysis of mass spectrometry data. @NatureMethods @WCMC_UCDavis @genomecenter @UCDavis @LiYuanyue #JRNLclub jrnlclub.org/research-films…

#StandWithUkraine With our lab research friends all over Europe and the US we protest against the Russian invasion. Solidarity now!

A new small molecule mass spectral search engine specdb.idsl.site #metabolomics

A paper from @WCMC_UCDavis proposes the use of spectral entropy as a measure of similarity for small molecule mass spectra, and the use of a one-bond-difference approach for improving false discovery rates. #Metabolomics @LiYuanyue nature.com/articles/s4159…

A good read and a nice piece of software. We've been able to integrate it directly into our GNPS Similarity Hub, so if your MS/MS are public, give it a try! gnps-similarity.ucsd.edu

The best gift for the holidays you can give yourself as a researcher is a publication. Our postdoc Yuanyue Le @LiYuanyue has in cooperation with @PaoloBonini6 a Nature Methods paper. We are very proud and happy for Yuanyue.🍾💐👏🍾 #metabolomics nature.com/articles/s4159…

Two of the most valuable resources out there on scientific writing: - @nature's guideline on abstract structure - Whitesides' 3-pager on outlining a research paper intra.ece.ucr.edu/~rlake/Whitesi… No need for entire books on how to write; these two short docs are amazingly instructive.