Lina Diaz-Gallo

Our unique work studying T-cells from the inflammation site of patients with myositis on a single-cell level is out 🧵1/3 embopress.org/doi/full/10.15… @KarineChem65601 @alexandra_argy @begum_h @AngelesShunashy

#Myositis can be grouped into eight subgroups of patients by combining genetic information and blood markers (#autoantibodies). The KI study is published in @eBioMedicine by @LinMarDiaz et al and may lead to improved diagnosis and treatment. #rheumatology doi.org/10.1016/j.ebio…

@gamonasterioo @bckbianca @ACDbio A beautiful pic

Diving deep into the psychedelic world of murine SI Swiss rolls with 3-plex #RNAscope. Done together with @bckbianca @ACDbio #FluorescenceFriday #RollRollRoll

@braraposo @karolinskainst 👏🏾👏🏾👏🏾

The second week of our Basic Immunology course has come to an end @karolinskainst. Thank you so much much to all the teachers involved and the fantastic students we had! Best wishes in your research endeavors!

Excited to share our editorial on #scRNAseq in idiopathic inflammatory myopathies, out today in @EmboMolMed Congrats to Argyriou et al on their study, advancing our understanding of this complex disease! @NosedaMichela @momina_yazdani @Mach_MD embopress.org/doi/full/10.15…

Autoantibodies profile and #HLA may help to better classify patients with #myositis Why? Check our study: sciencedirect.com/science/articl… @ingrid_lundberg @Leopad12 @drhectorchinoy @SarahLTansley @AngelesShunashy

Autoantibodies profile and #HLA point to pathogenic pathways in #myositis ⁩ Figure made by⁩ ⁦⁦⁦@AngelesShunashy⁩ ars.els-cdn.com/content/image/…

@KarineChem65601 @EmboMolMed Link to publication ⬇️ embopress.org/doi/full/10.15…

T cells in the muscle tissue of patients with idiopathic inflammatory myopathies was characterized by @KarineChem65601 et al in a study in @EmboMolMed. The results show that the same T cells persist in the muscle despite immunosuppressive treatment. news.ki.se/persistent-t-c…

Persistent T cells identified in the muscle of patients with idiopathic inflammatory myopathies | Karolinska Institutet Nyheter news.ki.se/persistent-t-c…

T-celler stannar kvar i musklerna hos myositpatienter trots behandling | Karolinska Institutet Nyheter nyheter.ki.se/t-celler-stann…

📢#SingleCellProfiling of muscle-infiltrating #Tcells in #IdiopathicInflammatoryMyopathies By A. Argyriou, B. Horuluoglu, @LinMarDiaz, @KarineChem65601 & colleagues @karolinskainst 🗞️ #openaccess: doi.org/10.15252/emmm.…

3/3 Identical expanded T-cell clones persisting at follow-up in the muscle of two patients suggest their involvement in disease chronicity.

Our unique work studying T-cells from the inflammation site of patients with myositis on a single-cell level is out 🧵1/3 embopress.org/doi/full/10.15… @KarineChem65601 @alexandra_argy @begum_h @AngelesShunashy

2/3 Clonally expanded T-cell clones were mainly found amongst cytotoxic and resident memory T cells implying their role in the disease pathogenesis.

1/3 We identified a tissue resident memory T-cell signature in the muscle biopsies of all patients with myositis included in this study

Sweden’s researchers outraged at decision to axe development-research funding go.nature.com/3rkyeVq

@alexandra_argy @riken_en @begum_h @AngelesShunashy @Myositis_KI Well done! Keep enjoying the course and Japan

Day 3 at @riken_en and here presenting our single-cell study in muscle-infiltrating T cells in idiopathic inflammatory myopathies @LinMarDiaz @begum_h @AngelesShunashy @Myositis_KI

Version 23 of the Human Protein Atlas is released including an updated genome assembly, a new Interaction section with data for human protein-protein interaction networks, and lots of other updates. Read more proteinatlas.org/news/2023-06-1…