Lukas Weiss

#ECMO aggravates platelet GPV shedding & δ-granule deficiency in #ARDS. ▶️New mechanisms mediating bleeding in critically ill pts ⁉️ @LabSchulze @LukasJWeiss, @NieswandtLab @mott_kristina @sfb1525 @DIVI_eV @ESICM @Uniklinikum_Wue #WuerzburgPlateletGroup jthjournal.org/article/S1538-…

The humanized platelet glycoprotein VI Fab inhibitor EMA601 protects from arterial thrombosis and ischaemic stroke in mice. Read more in #EHJ academic.oup.com/eurheartj/adva… @escardio @ESC_Journals #CardioTwitter #thrombosis

Highly Effective Thrombosis Inhibitor in Sight! Scientists @NieswandtLab @uniklinikum_wue present promising GPVI inhibitor EMA601 for efficient prevention and treatment of arterial #thrombosis and #inflammatory reactions without increased bleeding risk nachrichten.idw-online.de/2024/08/19/pla…

Happy that we were able to contribute to this exciting study under the lead of Karin Müller and colleagues. @uktuebingen @LabSchulze

Ein interdisziplinäres Team am #UKW hat den GPV-Rezeptor auf #Thrombozyten als Ziel gegen Blutungsereignisse bei ECMO identifiziert. Publ. im JTH, PM➡️ rb.gy/7ul1dn @LabSchulze @LukasJWeiss, @NieswandtLab @mott_kristina @sfb1525 @DIVI_eV @ESICM @dfg_public

Excited to attend my first ASH conference in sunny San Diego and present our data on MKs & platelets after HSCT 🙌 #ASH23 @LabSchulze

I am happy to share our most recent published article! Here we aimed to disrupt the previously described platelet GPVI dimerization site to study its role in vivo. doi.org/10.1016/j.thro…… @StefanoNavarro8 @StegnerLab @NieswandtLab @Platelets @ELShematology

Happy to share our state-of-the-art review now out in @BloodJournal: We summarize evidence that distinguishes the fascinating platelet mechanisms and signaling events that mediate inflammatory hemostasis: ashpublications.org/blood/article/…

Coffee lovers will love this new report ;-) academic.oup.com/eurjpc/advance… @escardio @BakerResearchAu @uk_biobank ☕️☕️☕️

I am very happy that our new manuscript from @LabSchulze on platelets in #sepsis and #COVID was accepted for publication in @BloodAdvances. Thanks to all the great people who contributed. @TR_240 @sfb1525 @NieswandtLab ashpublications.org/bloodadvances/…

Just published: #optogenetics in #megakaryocytes! @Katheri40844017, @Gao_SQ #GeorgNagel @TR_240, @Uni_WUE Optogenetic manipulation of cyclic guanosine monophosphate to probe phosphodiesterase activities in megakaryocytes | Open Biology royalsocietypublishing.org/doi/10.1098/rs…

Our latest study has just been published! In this publication, we show how targeting the same epitope on human or mouse GPVI can differently affect receptor function. @NieswandtLab @StegnerLab @TAPAS_ITN @RVZ_Wuerzburg @CARIMMaastricht mdpi.com/1422-0067/23/1…

3 days of Cardio-Immune crosstalk are almost over. Great talks today of Burkhard Ludewig and Jürgen Schrader! Thanks to everyone for joining and enjoying! 👏🏻 See you next year! ❤️ @medeinsUKW @DZHI_Wuerzburg @Helmholtz_HIRI @RVZ_Wuerzburg @KantonsspitalSG @UniklinikDUS

Procoagulant platelet sentinels prevent inflammatory bleeding through GPIIBIIIA and GPVI loom.ly/MsDPhI0

Proud of the excellent science, fantastic talks and posters presented by the group. Bright future ahead. #ISTH2022 #ISTHEarlyCareer #platelets

Data on a novel anti-GPVI an⁦tibody characterised in a humanized GPVI mouse Model presented by @StefanoNavarro8⁩ from ⁦@NieswandtLab⁩ at #ISTH

Ongoing experiment in S11A: what happens to platelets in vivo if you chill the human body to 4 °C? #ISTH2022 @isth Can we adjust the air-conditioning system?