Matteo Gastaldi

Severe anti-NMDAR encephalitis doesn’t always mean irreversible damage. In this international study led by Josep Dalmau & Mar Guasp), ~2/3 of patients in prolonged vegetative state (≥9 months) improved—1/3 fully. Late recovery is real. #Neuroimmunology thelancet.com/journals/laneu…

📢 We are #hiring #phd at IGNITION. 13 positions: Spain, Portugal, France, Italy, Germany, Poland, The Netherlands, Austria. Meet our associated partner Sonja Noss. Discover the Growtential and smartfullness with us sonjanoss.com Apply: ignition-consortium.eu

@OConnorLabYale and I are thrilled to share that our new study on MuSK myasthenia gravis (MG) has just been published in @Brain1878 !👇 (1/8) doi.org/10.1093/brain/…

@EliaSechi @GruppoNina Proud to be part of this common effort from out group!

Myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD): Practical recommendations for diagnosis and management by the NINA Group @GruppoNina 🇮🇹 - Journal of Neuroimmunology jni-journal.com/article/S0165-…

Epstein-Barr virus is a proposed trigger of multiple sclerosis, but the involvement of virus-infected B cells has remained unclear. @TheLuftigLab & team @PittTweet now identify atypical B cells expressing CXCR3, immune checkpoint molecules, and an EBV-associated pro-inflammatory phenotype from people with early MS. Full report: insight.jci.org/articles/view/…

Our new paper is finally out! A terrific joint effort to advance our understanding of T cell mediated neurodegeneration in AE ! “Neuronal pSTAT1 hallmarks synaptic pathology in autoimmune encephalitis against intracellular antigens” link.springer.com/article/10.100…

#CASPR2-#antibody diseases are provide clues to mechanisms of autoantigen-specific tolerance Here - in @ScienceAdvances - we show how central and peripheral B cell tolerance licences pathogenic CASPR2 antibody generation. science.org/doi/10.1126/sc… More below 👇🏿

Congratulations @Mayo_AING @neuro_bo @Johnsoltys4 and team for their elegant study delineating breakdown in central and peripheral tolerance in CASPR2 antibody positive encephalitis!

🗞️📰 We at TSF have some BIG news to share… pcori.org/research-resul…

Structural basis of aquaporin-4 autoantibody binding in neuromyelitis optica #NMOSD science.org/doi/10.1126/sc…

AQP4-specific T cells determine lesion localization in the CNS in a model of NMOSD actaneurocomms.biomedcentral.com/articles/10.11…

neurology.org/doi/10.1212/NX… Proud to share @StefanoMascio91 latest work on PLP1 antibodies in demyelinating diseases. PLP1 abs are mainly found in patients with non MS diseases with combined central and peripheral demyelination, but also in rare seronegative NMOSD

@Benjamin_Trewin This is a very relevant piece of work- now we just have to understand how to predict relapses timing- congratulations!

MOGAD: A comprehensive review of clinicoradiological features, therapy and outcomes in 4,699 patients globally sciencedirect.com/science/articl… 🧵Just published in Autoimmunity Reviews 🗞️: Our systematic review across 31 countries challenges fundamental assumptions about MOGAD! ⬇️👇

@neurotutto Amazing workshop raffaele thank you very much for organizing!

A great meeting! We had amazing insights from the speakers and the chairs!

@neuroimmuclinic @idibaps @hospitalclinic An amazing achievement for an amazing researcher!

We are happy to announce that Marianna Spatola is awarded an ERC Starting Grant for research into autoimmune encephalitis at @idibaps @hospitalclinic clinicbarcelona.org/en/news/idibap…

Happy to have led this work along with amazing researchers in the effort of improving the management of MuSK-MG. More work is needed to find prognostic markers of disease while better understanding the immunobiology of this disease. @UNI_FIRENZE @AOUCareggi @Unicatt @NDCNOxford