MJ

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MJ

@MJ_C12

Capital Formation @plcapital

Katılım Mart 2024
3.2K Takip Edilen47 Takipçiler
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Lacey
Lacey@lacey_wisdom·
At @plcapital we believe the GPT moment for robotics is closer than many believe, with innovation in the sector rapidly advancing and we see cryptographic and decentralized primitives as central to this narrative 🧵 1/5
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Mads
Mads@europemaxxed·
europeans after enabling their out of office auto reply until september
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Juan Benet
Juan Benet@juanbenet·
Here is Episode 2 of my new podcast dedicated to conversations on the future of neurotech, computing, intelligence, and more. My guest Dr. Ben Rapoport is co-founder and CSO of Precision Neuroscience (@PrecisionNeuro_), Assistant Professor of Neurosurgery at the Icahn School of Medicine at Mount Sinai, and Scientific Director at Mount Sinai. Previously, he co-founded Neuralink and Simbionics (acquired by Apple). Precision is building a minimally invasive brain-computer interface (BCI) that reads from thousands of points on the cortex without penetrating it. The Layer 7 device is implanted through a one-millimeter slit in the skull rather than the larger borehole other approaches require. It is also fully removable. Precision seeks to help the 5 million people living with severe paralysis in the US (including 800,000 new stroke cases per year). In March 2025, Precision received FDA clearance for a temporary wired version of the system. Over 85 patients have been implanted with and used the device in clinical studies (50 at the time of our conversation). Wireless implants are planned for 2027. We go deep on the history of Neurotech from the 1980s to the ML inflection points that triggered Neuralink's founding, why surface ECoG was a contrarian bet that's now paying off, the path to treating paralysis and stroke at scale, and why Ben believes neural data is at the same inflection point genomic data was in 2000 — a whole class of biological problems about to become tractable as computer science problems. Chapters 00:00:00 Introduction 00:04:39 Paralysis as a lens to understand the brain 00:05:36 The 1980s breakthrough: population encoding and the birth of BCI 00:14:36 Google Translate, ML, and the founding of Neuralink 00:23:08 What is the long-term vision of Precision Neuroscience 00:31:56 Layer 7 and why transformative technology looks impossible at first 00:50:21 The surgery: a slit in the skull, not a borehole 00:55:19 The clinical program: who are the patients 01:04:16 FDA clearance and the path to wireless implants in 2027 01:08:32 The patient population: paralysis and stroke at scale 01:16:26 Neural data as the new genomics 01:30:06 BCIs, AI, and the future of the human-machine interface 01:31:22 From medical necessity to lifestyle technology 01:40:36 Precision as a platform — and an optimistic vision If you're interested in these kinds of discussions, subscribe to the podcast. And if there’s anyone you’d like to see or hear on the podcast, reply with your suggestions. Full Episode 2 here and in other platforms below.
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Sean Tierney
Sean Tierney@scrollinondubs·
So @MJ_C12 and I built a thing yesterday at AgentsDay: a single MCP that lets you (or your agent) analyze a webpage, scan the top three prediction markets and returns any positive EV bets related to the content of the webpage. MIT open source. Built on @Cloudflare link below.
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The Startup Ideas Podcast (SIP) 🧃
The Startup Ideas Podcast (SIP) 🧃@startupideaspod·
POV: when you realize you are living through the greatest time in history to be an entrepreneur and it's time to lock in
GREG ISENBERG@gregisenberg

wake up because this is the GREATEST time in history to start a company with TRILLIONS of dollars up for grabs over the next 10 years 1. consumer mobile is INTERESTING again for the first time since like 2017. apps can actually do things now. do things. real things. book the flight, draft the contract, follow up with the lead, negotiate the rate, do things. we went from "tap to view" to "tap to deploy." the entire interaction model of software just flipped & most people haven't even registered it yet. OH, and the cost to create these apps is 1/100th of 2017. 2. HARDWARE is back on the table because you can shove Gemma 4 or DeepSeek onto a device that costs less than dinner & it runs locally with zero cloud costs. a year ago that sentence would have sounded insane. you can ship a physical product with a real brain in it now. the last time hardware was this accessible was the early smartphone era & that created a trillion dollar app economy from scratch. 3. literally EVERY category is open to be rebuilt AI-first. the incumbents know it & they're paralyzed. they can't move fast because moving fast because incumbents move slower than you (usually). that paralysis is your opportunity. build the app. build the SaaS. build the AI agent 4. distribution is FREE. you can go from zero audience to 10,000 people who trust you in 90 days on X or YT or IG your first 100 customers are sitting in your replies right now. the old playbook of "raise money, hire sales team, buy ads" is being lapped by a solo founder with a twitter account & a working demo. Oh, and you can use AI to automate a lot of it (ideas, research, AI avatars etc) 5. Idk about you but it feels like companies are doing LAYOFFS like it's the great depression and it's only getting started. No job is secure. So, building a side project that could turn into the main project is more important than ever. 6. the ENTIRE economy is being repriced in real time. the surface area for new companies has never been wider. the tools to build are free. the models are open source. the incumbents are running committees about their "AI strategy" while you could have already shipped. and somehow the predominant response from most people is to watch youtube videos about it & go back to their 9-5. not saying this is easy not saying everyone will win but im saying right now is a time worth trying YOU ARE LIVING through a mass reshuffling of who owns what & who builds what. the last time this happened was the internet itself. before that, electricity. this almost never happens. & you're sitting there doing nothing about it? wake up.

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Juan Benet
Juan Benet@juanbenet·
Excited to launch a new podcast dedicated to conversations on the future of neurotech, computing, intelligence, and more. First guest: @maxhodak_ founder & CEO of @ScienceCorp_, which is building PRIMA, a retinal prosthetic that’s restoring meaningful vision for patients with blindness caused by age-related macular degeneration. Science is also developing a biohybrid brain implant that grows living neurons directly onto a silicon chip, then interfaces that system with the cortex. The possibility space here is vast and new. Imagine growing new areas of the brain. Sections 00:00 What counts as neurotech? 01:45 History of brain-computer interfaces and the smartphone dividend 07:25 PRIMA - How Science is restoring vision in blind patients 10:10 Why stimulating bipolar cells works when the optic nerve doesn't 30:30 Are we bottlenecked by biology or engineering? 32:40 Expanding the brain's bandwidth beyond 10 bits per second 37:00 Can we add new areas to the brain? 37:46 Biohybrid BCIs: neurons growing on a chip 39:20 What could neural augmentation look like? 01:13:20 How Science drives Fast R&D 01:44:00 How founders learn and level up This is the kind of discussion I’m excited to explore on this podcast. Enjoy! Full Episode 1 here and in links below.
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Joey Politano 🏳️‍🌈
Joey Politano 🏳️‍🌈@JosephPolitano·
the strait of hormuz is in a quantum superposition of open and closed that only collapses when you try to take a tanker through yourself and see if you get shot at
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Javier Blas
Javier Blas@JavierBlas·
The world’s most important price for physical oil barrels soared to its highest on record. Dated Brent, which helps price much of the world’s actual oil barrels, hit $144.42 on Tuesday, according to Platts, a unit of S&P Global Energy.
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Javier Blas
Javier Blas@JavierBlas·
".... The current crisis is more serious than those of 1973, 1979, and 2022 combined..." — Fatih Birol (In French) lefigaro.fr/conjoncture/fa…
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Not Jerome Powell
Not Jerome Powell@alifarhat79·
Ladies and gentlemen, the president of the United States of America. Unbelievable
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Ethereum Foundation
Ethereum Foundation@ethereumfndn·
Today, several teams at the EF are launching pq.ethereum.org, a dedicated resource for Ethereum's post-quantum security effort. What started with early STARK-based signature aggregation research in 2018 has grown into a coordinated, multi-team effort, all open source. The Post-Quantum team and Cryptography teams, with help from the Protocol Architecture and Protocol Coordination teams, have been working on this body of work for 8+ years. At pq.ethereum.org you'll find: - How PQ impacts each protocol layer - The full PQ roadmap (strawmap.org) - Open resources: repos, specs, papers, EIPs - FAQ: 14 questions across 5 categories, written by the PQ team - A 6-part lean Ethereum interview series (@zeroknowledgefm) - Interest form for the 2nd Annual PQ Research Retreat (Cambridge, UK, Oct 2026) - 10+ client teams are already building and shipping devnets weekly through PQ Interop. All the work is public and all of it is open. pq.ethereum.org
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Vinay
Vinay@leashless·
rmi.org/insight/winnin… I worked on this book about the end of the age of oil 20 years ago Oil has always been THE national security risk: the world runs on flammable gas in thin steel pipe. You poke a hole and the world burns.
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Aaron Rupar
Aaron Rupar@atrupar·
Powell: "The thing a good number of people on the committee are concerned about is the very very low level of job creation. If you adjust what has been the trend job creation over the past 6 months for what we think is the overstatement due to overcounting, effectively there is 0 net job creation in the private sector"
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Protocol Labs
Protocol Labs@protocollabs·
🚀 Protocol Labs Demo Day W26 is live. Discover 12+ startups building across AI, web3, and deep tech. • 3-minute founder presentations • Decks available to review • Direct introductions Browse everything async through March 23. Log in. 👇 directory.plnetwork.io/demoday/plw26
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Protocol Labs
Protocol Labs@protocollabs·
📅 Save the date: Protocol Labs Demo Day is March 16. Explore 12+ startups across AI, web3, and deep tech sharing what they’re building. The format is simple: • Watch 3-minute founder presentations • Review decks • Request introductions directly Fully async. No livestream required. Materials remain available through March 23, so you can browse whenever it works for you. Investor registration. 👇 directory.plnetwork.io/demoday/plw26
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