Dr Michelle Percharde

👏🏻👏🏻👏🏻 We are so happy to announce that @BPernaute from #CABD was awarded an #ERCCoG @ERC_Research grant! Barbara will study different processes that occur in the early embryonic development! Way to go! 🧬🔬

Happy to share our latest #preprint showcasing the work done during my postdoc in the lab of @MPercharde at the @MRC_LMS. We used CRISPRa to disentangle the close relationship between Dux and MERVL elements in the induction of the 2-cell like state. biorxiv.org/content/10.110… (1/8)

Weekend spa hotel report: I can’t help but notice design parallels with modern #cryoem microscopes, in this ‘Cryo therapy treatment’ device I found on site. I doubt CRYOACTION is trade marked, @thermosciEMSpec @JEOLEUROPE in case you like the look.

📣Sharing the latest research from the @MRSantosLab, just released on bioRxiv! We found LINE1 RNA promotes nuclear compartmentalization to repress the 8-cell state in human embryonic stem cells. biorxiv.org/content/10.110… 👇Key findings:

FUNDED PHD OPPORTUNITY: Defining the rate limiting steps of differentiation tempo through deterministic forward programming with Dr Teresa Rayon Apply by 24th November Find out more: babraham.ac.uk/work-and-study… #PhD #PhDVacancies #PhDStudents #PhDProjects

Happy to officially join the @MRC_LMS as MRC Investigator and Programme Leader Track. Excited to be surrounded by outstanding, nurturing, collaborative colleagues! For more details, please visit the Lab webpage Genetic Variations and Disease, Lila Allou (mrc.ac.uk)

I happily wrote a Preview for the recent HUSH2 story @MolecularCell from the Tchasovnikarova lab Preview: tinyurl.com/5n6jrwut Article: sciencedirect.com/science/articl… The HUSH-HUSH2 link from L1 transcription to innate immunity could complicate efforts to target L1 in disease.