Gregory Wu

Looking forward to joining Dr. Jiwon Oh at a @PeerView live symposium during #CMSC2026 on advancing care in #MultipleSclerosis, including the role of #BTKi. Join us 5/27 at 5 PM EDT in Charlotte or virtually: bit.ly/CharlotteMS26-T #Neurology #MedEd

Excited to see our work published in @GreenJournal group! We show that cladribine profoundly reshapes the CSF cell landscape in MS, providing new insights into treatment effects within the CNS. Thanks to all, especially @MS_ResearchDoc and Roman Smirnov! doi.org/10.1212/NXI.00…

New Pathways, New Possibilities in #MultipleSclerosis: Enhance your ability to interpret clinical data to identify ideal candidates for #BTKi therapy with Drs. Jiwon Oh and Gregory F. Wu (@MS_ResearchDoc), 5/27 at 5:00 PM EDT: bit.ly/CharlotteMS26-T #CMSC2026 #neurology

Overjoyed to share our new work exploring the antigen specificity of CSF-expanded CD8+ T cells in #multiplesclerosis #EBV in @natimmunol 🧵1/ nature.com/articles/s4159…

🚨 Paradigm shift in #MultipleSclerosis 🚨 New study in Nature Medicine shows MS is not fixed subtypes but a dynamic continuum of states across 4 dimensions: disability, brain damage, relapses & silent inflammation. 📖 Read: nature.com/articles/s4159… #MS #Neurology #AI

CSF cell analysis is key to understanding neurological diseases but has been limited by cell fragility. Millet Wallisky et al. introduce a rapid, one-step method for efficient CSF immune profiling Check out the paper below 👇 jni-journal.com/article/S0165-…

Murphy Lab Bay #2: proving that science and chaotic shenanigans can coexist. 🙌 @SunnyKimNov2016

Pleased to write this editorial with Larry Steinman about a potential novel antibody in MS neurology.org/doi/10.1212/NX… Original manuscript here: neurology.org/doi/10.1212/NX…

Happy to share this collaborative work looking at long term results of a high efficacy DMT in early #MS #ocrelizumab ⁦@OMRF⁩ ⁦⁦@AaronBosterMD⁩ ⁦@drbarrysinger⁩ ⁦@Brandon_Beaber⁩ ⁦@MSViewsandNews⁩ neurology.org/doi/10.1212/WN…

So proud of this collaborative work! Thanks to all involved, including @Clodida @BrianEdelson2 @maxim_artyomov @mzhlab @jsabatino37

@mzhlab I am proud to share our manuscript published in @ANA_journals today. 🥳doi.org/10.1002/ana.27… We used data-driven approaches to analyze paired #CSF and blood #FlowCytometry of 8,790 (discovery) + 3,201 (validation) patients. A #tweetorial 🧵1/16

Exciting news! Our new paper is published at Annals of Neurology! Check it out to see how large-scale CSF and blood flow cytometry can reveal disease clusters to improve diagnosis and understanding doi.org/10.1002/ana.27…

Using sc-RNA-Seq to delineate T cell changes in AD, demonstrates an up regulation of exhaustion markers in CD8+ T RM cells within 5xFAD mouse brain. Check the link below 👇 jni-journal.com/article/S0165-…

@SaligramaLab I gotta get a pair of those shoes!

#Trio who firmly in the existence of #CD8 #Regulatory #Tcells

I'm excited to announce that Jennifer Lawrence's thesis work is now out! Check it out here: JCI Insight - Microglia drive diurnal variation in susceptibility to inflammatory blood-brain barrier breakdown insight.jci.org/articles/view/…

Post-mortem MS brain display PD1+ Granzyme B+ tissue-resident memory (Trm) T cells in MS lesions, in contact with EBV infected B cells promoting local CNS inflammation. Check out👇 this 2023 interesting study from @FrancescaAloisi sciencedirect.com/science/articl…

@MS_ResearchDoc @KateSadlerPhD Another super important TRP paper that I just came across because of a new paper on how fever impacts CD4 T cell responses by @DarrenHeintzman. Linking the TRPV paper here to add it to this thread: pubmed.ncbi.nlm.nih.gov/32839313/?s=08

Excessive and repetitive Ampicillin treatment alter the gut-brain axis. Ampicillin induce neuroinflammation through NfL, NOS2 and GFP release. Check out 👇 the work by @TouilBoukoffa team. jni-journal.com/article/S0165-…

Incredibly excited to share our latest work exploring the antigen specificity of clonally-expanded CSF-enriched CD8+ T cells in MS  #multiplesclerosis #Tcells #EBV 🧵1/ biorxiv.org/content/10.110…