Marc Siggel

253 posts

Marc Siggel

Marc Siggel

@MSiggel

Postdoc @embl @EMBLHamburg | former PhD at @MPIbp

Hamburg, Germany Katılım Mart 2018
323 Takip Edilen244 Takipçiler
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Marc Siggel
Marc Siggel@MSiggel·
The models were so complete that we could perform coarse-grained MD simulations including the double membrane with ~100k lipids, and approximately 13.5 Million particles! So much to learn from this massive system. This is only the beginning🤩 #AlphaFold #cryoEM
Jan Kosinski@jankosinski

We combined #AlphaFold and #cryoEM to build a new model of the nuclear pore complex, the largest complex in the human cell! The structure covered by the model is 15x bigger than the human ribosome and 2x bigger than old nuclear pore models. 1/7 Read how: biorxiv.org/content/10.110…

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Google DeepMind
Google DeepMind@GoogleDeepMind·
Huge congratulations to @DemisHassabis and John Jumper on being awarded the 2024 Nobel Prize in Chemistry for protein structure prediction with #AlphaFold, along with David Baker for computational protein design. This is a monumental achievement for AI, for computational biology, and science itself. 🧬
The Nobel Prize@NobelPrize

BREAKING NEWS The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”

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@gecht@chaos.social
@[email protected]@_mischi·
Vision Pro is cool and all, but have you ever spent time searching for that format error in your YAML file? Apple just open sourced their new type-safe configuration language Pkl. Define once, and safely render into many formats! pkl-lang.org/blog/introduci… github.com/apple/pkl
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Marc Siggel
Marc Siggel@MSiggel·
PyTME is finally out in Software X! 🖥️ If you've always wanted to try template matching on your cryo-ET data, now is a great time to start! ⏩ PyTME is fast, runs on multiple CPUs and GPUs, automatically optimizes RAM usage, and, and, and 🚀🚀 #teamtomo sciencedirect.com/science/articl…
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Matt Sikora
Matt Sikora@BioPhysMatt·
Always wanted to run simulations of extracellular matrix, but didn't know where to start? Search no more! Exciting postdoc position @MCB_UJ in our #dioscuri lab, lots of MD sims, great experimental collabs, and, as always, good coffee ☕️ tinyurl.com/4v5ahkjn Deadline 06.02!
Matt Sikora tweet media
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Weria Pezeshkian
Weria Pezeshkian@WPezeshkian·
Our FreeDTS (software) work finally got published in Nat. Commune. Exciting new features are under development and will be released soon. nature.com/articles/s4146…
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VanniLab
VanniLab@LabVanni·
We are looking for 1 PhD and 1 Postdoc to work on MD simulations of lipid metabolism funded by @snsf_ch. Interviews will start in Jan. Excellent salary, resources, colleagues and collaborators. Plus the science is great (but I am biased...)! Contact me by email if interested.
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Sergei Yakneen
Sergei Yakneen@SergeiIakhnin·
I’m incredibly proud to share this joint work by @IsomorphicLabs and @GoogleDeepMind on the latest version of AlphaFold, demonstrating SOTA on a wide variety of tasks, including protein-ligand structure, nucleic acids, PPIs, and PTMs.
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Google DeepMind
Google DeepMind@GoogleDeepMind·
Uncovering the causes of disease is one of the greatest challenges in genetics. 🧬 To help advance this, we created AlphaMissense: an AI model classifying missense variants - or genetic changes affecting proteins. Here's how it can help scientists. 🧵 dpmd.ai/alphamissense-…
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Keşfet

@EMBLHamburg @CssbHamburg @WPezeshkian @jankosinski @DemisHassabis @CellCellPress @MCB_UJ @MPIbp