Marc Cohen

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Marc Cohen

Marc Cohen

@MarcACohen

Biotech and Software entrepreneur, CEO, and Chairman.

Zoom Katılım Mart 2011
489 Takip Edilen427 Takipçiler
Marc Cohen
Marc Cohen@MarcACohen·
A new @MooreLab preprint paper describes the use of a cyclic coordinate descent algorithm to construct the energy landscape of PROTAC-mediated protein-protein interactions, opening up the possibility of adding design capabilities to #proteindegradation. bit.ly/3nnB9bX
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Marc Cohen
Marc Cohen@MarcACohen·
If you haven’t, check out the newest issue of the Degrader Digest where we highlight new companies in the space, additional biology animations, and an updated list of industry events. We also include recent media articles and scientific papers: bit.ly/3CbYcuh
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Marc Cohen
Marc Cohen@MarcACohen·
Assessment of #proteindegradation efficacy requires measurement of protein levels in cells: the @fischerlab1 recently published these protocols on how to quantify cellular protein levels and the corresponding tools for analyzing the data. bit.ly/3nvZZGH
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Marc Cohen
Marc Cohen@MarcACohen·
In a recent #JMedChem article, authors share their perspective on the recent advances in molecular glues for targeted #proteindegradation & discuss challenges in developing molecular glues into therapeutic agents. bit.ly/3xFL4uB
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Marc Cohen
Marc Cohen@MarcACohen·
PROTACs consist of a target binding unit, a linker & an E3 ligase binding moiety. A new @FrontChemistry review compares different synthetic opportunities to connect E3 ligands & describes the chemistry of linker attachment. bit.ly/3s6jJk7
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Marc Cohen
Marc Cohen@MarcACohen·
Want to be notified when a new issue of the Degrader Digest is released? Sign up with the following link and we will deliver the next release right into your inbox! bit.ly/3b1cvqy
Marc Cohen tweet media
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