Mark Damante, MD

🧬 New publication in the Journal of Neurosurgery highlighting advances in CT-guided robotic delivery approaches for targeted brain therapeutics. Congratulations to @MarkD_Jr and colleagues on this work: go.osu.edu/DHry #GeneTherapy #Neurosurgery #Robotics

A promising new drug therapy developed by #OSUWexMed neurosurgeon Dr. Shahid Nimjee may hold the key to providing effective treatment to stroke victims and solving one of the biggest complications in strokes: bleeding. health.osu.edu/discovery-and-…

Just out in @TheJNS from Mark Damante, MD, (@MarkD_Jr ) and @NeurosurgeryOSU. CT-guided cranial #robotics were used to place multiple bilateral convective delivery cannulas in less than 30 min with sub-mm accuracy. This technique can be applied to a wide variety of convective perfusion therapies, including gene therapy. #Neurosurgery #CED #imaging #genetherapy thejns.org/view/journals/… @OhioStateMed @OSUWexMed

⚽️ Great way to wrap up the Gene Therapy Symposium – Columbus Crew match with an incredible group. We’re already looking forward to next year.   #GeneTherapy

🧬 Today’s the day.   The 2nd Annual Gene Therapy Symposiumbegins this morning in Columbus. We’re excited to welcome researchers, clinicians, and industry leaders for two days of discussion, collaboration, and innovation in gene therapy.   #GeneTherapy #GenomicMedicine

Honored to have OSU neurosurgery alumnus, Dr. Peruzzi from @BWHNeurosurgery @harvardmed, as our visiting professor for our annual John McGregor, MD lectureship!

Great talk today by Dr. Brad Elder (@NeurosurgeryOSU) on CNS drug delivery, advantages of convective delivery of therapeutics, lessons learned from past clinical trials and exciting new trials using convective delivery for glioma.

@MatthieuDWeber (exceptional MS4 @OhioStateMed) presented his work on once-functional outcomes following resection of brain metastases in eloquent motor cortex at the @OSUWexMed inaugural Multidisciplinary Neuro-oncology symposium where he won a best poster presentation award!

🧬Program Highlight Columbus is emerging as a hub for #genetherapy innovation. At the 2nd Annual Gene Therapy Symposium, leaders from across academia, industry, and investment will discuss: "How Gene Therapy is Shaping the Biotech and Innovation Landscape in Columbus."

We are thrilled to announce our 2026 match class! Welcome to Ohio State Neurosurgery! #matchday2026

@MatthieuDWeber did an amazing job @NASBSorg presenting our @NeurosurgeryOSU strategy for large anterior fossa #meningiomas @OSUCCC_James

We are excited to be one of the host institutions for the new Expanse program for US medical students without a home neurosurgery program! Apply now for the chance to spend the summer learning essential neuroscience techniques!: neurosurgery.ucsf.edu/expanse-program

@NeurosurgeryOSU @OSUGeneTherapy #Neurosurgery #GeneTherapy #Innovation

Robotic-assisted placement of convective delivery cannulas enhances access to previously difficult-to-reach deep brain structures, like the cerebellar dentate nucleus, while maintaining precision and improving efficiency. #Neurosurgery #GeneTherapy journals.lww.com/onsonline/full…

Just out in @NeurosurgeryCNS, a study led by @MarkD_Jr (@NeurosurgeryOSU), demonstrates the feasibility, effectiveness and efficiency of robot-assisted placement of convection-enhanced delivery cannulas in the brain. This advance can streamline and enhance direct infusion of therapeutics to the brain. #neurosurgery #CED #GeneTherapy @OhioStateMed @OSUWexMed @Solid_Bio @CNS_Update @OSUGeneTherapy journals.lww.com/onsonline/abst…

Gene therapy research, by ⁦@NeurosurgeryOSU⁩ neurosurgeons, ⁦@RussellLonser⁩ and Brad Elder, M.D., offer insights into tumors and neurologic disorders. #neurosurgery #GeneTherapy ⁦@OhioStateMed⁩ ⁦@OSUWexMed⁩ ⁦@OSUCCC_James⁩ thelantern.com/2026/02/advanc…

#OnlineFirst: Direct image-guided convective perfusion of the bilateral thalami for gene therapy in frontotemporal dementia: technical note. thejns.org/view/journals/…

🧬This is an important milestone for the #FriedreichsAtaxia community. #RareDiseaseResearch

Yesterday, Solid Biosciences shared an important update with the Friedreich’s ataxia community. The first participant has been dosed in the Phase 1b FALCON trial evaluating SGT-212, our novel, investigational dual-route administration gene therapy for the treatment of FA. We are deeply grateful to the FA community, @CureFA_org, our clinical partners, and the patients and families whose trust and participation make this work possible. Your partnership continues to guide our mission to advance meaningful therapies for people living with FA. Read the full community letter here: solidbio.com/letter-to-the-… #FriedreichsAtaxia #FACommunity #RareDiseaseResearch

Mark Damante, M.D., (@MarkD_Jr) and colleagues (@NeurosurgeryOSU and @OhioStateRadOnc ) show (@JNeurooncol) that for intermediate-sized motor-cortex #metastases, patients benefit from surgical resection plus #SRS compared to SRS alone. These foundational findings demonstrate the critical role that resection plays in optimal patient outcome for metastatic deposits in functional areas. link.springer.com/article/10.100… #NeuroOncology #neurosurgery #BrainMetastasis #RadOnc #MotorCortex #ClinicalOutcomes #OncologyResearch #XMed @OhioStateMed @OSUWexMed @OSUCCC_James @joshuapalmermd