Matthew Rook

@Stephanie_A_H @biorxiv Fantastic! Amazing work Stephanie and company!

And just before the Christmas break, we put our latest ASIC work on @bioRxiv. #ionchannels We reveal how pH-dependent conformational changes contribute to different types of desensitization in acid-sensing ion channels. biorxiv.org/content/10.110…

As a manual patch clamper, I’d say this is spot on

@LonnieWollmuth @Miaomiao_He_ Congrats Lonnie and @Miaomiao_He_ !! Looking forward to reading and good luck with the poster!

Our paper: ‘Two gates mediate NMDA receptor activity and are under subunit-specific control’ just got accepted at Nat. Comm. perfect timing since Miaomiao He @Miaomiao_He_ will be presenting tomorrow. 1:45 PM. B349.

#OnThisDay in 1914 English physiologist, Sir Alan Hodgkin was born. Hodgkin won the @NobelPrize for #Physiology or #Medicine in 1963, alongside Sir Andrew Huxley & Sir John Eccles for their analysis & mathematical description of the basis of the nerve impulse and its propagation.

Opening the latest version of the document I'm currently writing

@MariaMusgaard Congrats Megan!!

@LonnieWollmuth @noelecertain Congrats Noele!!

⁦@noelecertain⁩ Noele officially defended her thesis today. Great job!!!!! No pictures of celebration since I had to dash for airport!! But the lab had a big celebration.

Gonna have to throw on the trilogy now

@KammermeierL @MariaMusgaard Thanks Paul, I definitely will

@MatthewRook9 @MariaMusgaard Good luck. Keep in touch!

Well, all packed and ready to move to Boston tomorrow. Anyone have recommendations on food in Cambridge?

@MariaMusgaard Thanks! I’m quite excited to start this new chapter

Pro tip - keep up on your plasmid inventory or you’ll end up miserable in your last days in lab, like me.

For PhD students it's a good idea to gamble on new PIs, on average they are more into it. I often see that the first graduate students that join a lab end up being really successful.

@Nicole_Paulk mt.com/us/en/home/pro… We bought this one about a year ago, still going strong. Fairly basic but our kinetic analyses of pH-gated channels show that it’s still on the nose even after a year!

Calling #scitwitter #biotwitter #chemtwitter does anyone have a pH meter they actually like? Easy to use, easy to clean, accurate, not fussy, simple user interface, lasts longer than 1 year before croaking? Please comment below! 🙏

@PSBROOKES @UR_Med This is a good point. I know it is hard on PIs especially with stagnant R01-like funding and the university doesn’t do anything to help (except for tuition “waiver” that’s essentially BS anyway)

@PSBROOKES @UR_Med A few thousand (4-6k) more per student shouldn’t break the bank, when grad students do most of the heavy lifting (esp. in our dept). This could also push more students towards applying for fellowships to lessen the burden on the lab.

if I’m reading recent SCOTUS abortion decisions right, I can force conservative justices and Republican legislators to rear botfly larvae under their skin for me and hold them liable if they don’t mature properly

baklava, if made correctly, is probably the single greatest dessert in the history of humanity

How about they do this study again using data from 2022 and see if we even fall in the top 10.