Stephanie Heusser

Last week’s Ion Channel Virtual Symposium 2.0 was quite the event! Two days. Ten speakers. Ion channels and transporters: PIEZOs, SLC26A5, ELKIN1, Navs, chemotactile receptors, SCL9C1 and TMEM165. If you missed it, here's a brief overview for you 🧵 #ionchannels

🚨 Reminder: The virtual Ion Channel Symposium 2.0 is happening next week! We have a fantastic lineup of speakers ready to share the latest discoveries in the field. Don’t miss out—sign up and join us for free! ✨ eventsignup.ku.dk/channels2024/s… @sm_usher @HomannPoulsen @ChowHanChua

Next, Navid Bavi (@ForceFromLipid) from UCLA will tell us about the molecular mechanism of mechano-electricial feedback in cochlear hair cells. We are all ears! 🐬🔊👂

For all #ionchannel enthusiasts out there: sign up for the second round of our Novel Ion Channel Symposium! eventsignup.ku.dk/channels2024

Our paper is finally published in PNAS - doi.org/10.1073/pnas.2…! It took over a year, but we are incredibly proud of the progress we've made in understanding NALCN #pharmacology. Congrats to @kathistt, @sm_usher, @LabPless, Oscar Serra and Vincenzo Carnevale! 🍻

@ChowHanChua @nhmrc Congratulations Chow🎉🎊 I'm looking forward to seeing all the research that comes out of your lab!

I still can't believe that I've been awarded an @nhmrc EL1 Investigator Grant! This will allow me to continue my research on NALCN function and pharmacology. 🔬👨‍🔬

@eriklindahl @BiophysJ Thanks Erik!

The final version of our study on #ASIC desensitization is now available! We show how a mutation in the β11-12 linker impairs desensitization while retaining conformational changes of the ECD and upper TMD. Full story here at @BiophysJ: authors.elsevier.com/a/1ix3k1SPT7sPc

We would also like to thank our reviewers for their constructive comments on the manuscript. We are grateful for funding from @Lundbeckfonden, @HorizonEU, and Brødrene Hartmanns Fond that enabled this project.

Congratulations to Caroline Marcher Holm, Aslı Bahar Topaktaş, and Johs Dannesboe, who recorded these data as part of their Master's project in our group. Thank you to @LabPless for letting me take the lead and for providing excellent support.

🤩🤩🤩 our work made it to the @NatureSMB cover. And then for such a great issue 🤩🤩 thanks to @VKalienkova @TimLynagh and Mowgli 🥳🥳 check @KatCiazynska comments 👇🏼

Online now! Protein semisynthesis underscores the role of a conserved lysine in activation and desensitization of acid-sensing ion channels. Research by @Debayan98488480, @GalleanoIacopo, @LabPless et al. @CellChemBiol #BPS2024 hubs.li/Q02kvH550

10 months ago, we shared our discoveries of NALCN's pharmacological secrets by unplugging its lateral fenestrations. Since then, we have dug deeper into NALCN's inner cavity, where we struck gold—we found the first drug binding site of NALCN! 🤓 tinyurl.com/5f9t552b

Ion channel people! Consider applying for the Ion Channel GRS/GRC happening this summer! I’m happy to be co-chairing the GRS with @AnabelFMarinho. We’ll definitely make it a fun one! Apply here: grc.org/ion-channels-g… grc.org/ion-channels-c…

@MatthewRook9 @biorxiv Thanks Matthew! Lots of references to your work, of course!

@Stephanie_A_H @biorxiv Fantastic! Amazing work Stephanie and company!

And just before the Christmas break, we put our latest ASIC work on @bioRxiv. #ionchannels We reveal how pH-dependent conformational changes contribute to different types of desensitization in acid-sensing ion channels. biorxiv.org/content/10.110…

@psalmotoxin @biorxiv Thank you!

@Stephanie_A_H @biorxiv Congratulations! One for my reading list 😃

@SwissIonChannel @LabPless @biorxiv Thank you, Hugues!

@Stephanie_A_H @LabPless @biorxiv Bravissima !

@ntoniosPantazis @biorxiv Thank you, Antonie! It has been great to see, what the master's students can achieve during their projects. Looking forward to seeing you at the Biophysical Meeting in February!

@Stephanie_A_H @biorxiv Congratulations, I really look forward to reading it! Data look spectacular 👏

Congratulations to Caroline, Asli, and Johs, and thank you to @LabPless for letting me take the lead on this.