Max Koppers

So excited and grateful that @ERC_Research #ERCStG will fund my project RNA.ORG to investigate the molecular mechanisms that regulate mRNA localization in neurons! There will be positions opening soon so get in touch if you are interested! @FGA_lab @VUamsterdam

The next speaker on the stage is @MaxKoppers #celltransportconf

very cool paper! FMRP regulates MFF translation to locally direct mitochondrial fission in neurons | Nature Cell Biology nature.com/articles/s4155…

RNA granules in flux: dynamics to balance physiology and pathology — a Review by Michael A. Kiebler & Karl E. Bauer go.nature.com/3UCa0Se

Check out our preprint using imaging-omics to characterize the #OrganelleSignature - the morphology interactions & distribution of #ER❤️ #Lysosomes🩵 #Mitochondria💚 #Peroxisomes🧡 #Golgi💛 & #LipidDroplets🩷 - of live #neurons and #astrocytes! doi.org/10.1101/2024.1… 🧵1/11

APEX peroxidase is a versatile tool for proximity labeling and electron microscopy (EM) but its requirement for toxic H2O2 is a liability. We now report LaccID, a multicopper oxidase evolved from an ancestral fungal laccase that oxidizes aromatic substrates using non-toxic O2 instead of H2O2. We use LaccID for EM imaging of cultured cells and fly brains, and for proteomic mapping of the changing surface composition of T cells that engage with tumor cells via antigen-specific T cell receptors.

Beyond thrilled to present our O-MAP—now *published* @naturemethods (!!!) O-MAP is a powerful new method for biochemically "dissecting" the subcellular microenvironment around an RNA of interest, using off-the-shelf parts and standard manipulations. 🧵 nature.com/articles/s4159…

Spatiotemporal dynamics and selectivity of mRNA translation during mouse pre-implantation development biorxiv.org/content/10.110…

Neuromuscular dysfunction in patient-derived FUSR244RR-ALS iPSC model via axonal downregulation of neuromuscular junction proteins biorxiv.org/content/10.110…

Light-induced targeting enables proteomics on endogenous condensates 🤯 cell.com/cell/fulltext/…

IGF2BP1 phosphorylation in the disordered linkers regulates ribonucleoprotein condensate formation and RNA metabolism: nature.com/articles/s4146…

Ataxin-2 polyglutamine expansions aberrantly sequester TDP-43 ribonucleoprotein condensates disrupting mRNA transport and local translation in neurons cell.com/developmental-…

Getting ready (rushing) for #SfN24?Us too!😃 Excited about Neuron, Glia, RNA, Plasticity, FXS or Local Translation?Us too!😃 Come join us Tues 8th, with 14 great (&short!) talks on emerging roles of axonal, dendritic, glial proteostasis in health & disease pls spread the word!

We are hiring! If you are looking for a PhD position and are interested in cellular and molecular neuroscience, consider applying! @FGA_lab @VUamsterdam @ERC_Research Please share 🙏 workingat.vu.nl/vacancies/phd-…

AXON2025 is gearing up! If you're passionate about neural circuit development, this is the must-attend event of next year — set in an extraordinary, non-conventional location🚢that you won’t want to miss! #AXON2025 @JeroenPasterk

bioRxiv: Cytoplasmic ribosomes hitchhike on mitochondria to dendrites dlvr.it/TDBq1d

@blibep @ERC_Research @IBDMmarseille Congratulations Baptiste!!

Conference in Grenoble 3th and 4th December 2024 "Organelles Transport in Health and Disease" --> Registrations are now open!! cell-transport.sciencesconf.org/?lang=en

@AgChaigne @ERC_Research @FGA_lab @VUamsterdam Thanks Agathe! And I see I can also congratulate you! Fantastic news! Congrats!! StG buddies 😉

So excited and grateful that @ERC_Research #ERCStG will fund my project RNA.ORG to investigate the molecular mechanisms that regulate mRNA localization in neurons! There will be positions opening soon so get in touch if you are interested! @FGA_lab @VUamsterdam

@anilevetu @ERC_Research @FGA_lab @VUamsterdam Thanks Evelina! Sounds like a good plan!