

Mehl lab
46 posts

@Mehl_lab
The Mehl Lab develops genetic code expansion to site-specifically incorporate non-canonical amino acids (ncAAs) into proteins. (Twitter run by students)



🚨🚨All genetic code expansion enthusiasts, don’t miss the GCE 2024 conference this summer (gceconferences.org)! Fantastic speakers both from academia and industry. Please retweet! @klanglab @Mehl_lab

An autonomous E. coli system to genetically encode a functional nonhydrolyzable phosphoserine mimic into proteins is created and used to reveal how 14-3-3 phosphorylation rewires its interactome. NEW #ASAP by Richard Cooley & team at @OregonStateBB Read: go.acs.org/4Ra






14-3-3s are such cool proteins, and still have ambiguous function given how many other proteins they interact with. If you like PTMs, too check out my latest pub in @ProteinSociety journal Protein Science! These were my first structures ever solved! doi.org/10.1002/pro.45…

Genetic encoding of 3-nitro-tyrosine reveals the impacts of 14-3-3 nitration on client binding and dephosphorylation biorxiv.org/cgi/content/sh… #bioRxiv












PermaPhosSer: autonomous synthesis of functional, permanently phosphorylated proteins biorxiv.org/cgi/content/sh… #bioRxiv
