

Michelle Funk
5.6K posts

@MichelleFunk3
#MentalHealth Policy & Service dev #QualityRights #humanrights #CRPD, psychosocial disability. Follow @WHO for official tweets
















Sixty years ago, studies were done comparing antidepressants with what is called “active placebos,” drugs that mimic the side effects of antidepressants. The conclusion? Almost no difference in outcome. Reading about the results of these 1960s studies was a lightbulb moment for British psychiatrist @joannamoncrieff. She was a junior psychiatrist at the time working in a mental hospital in the UK, and she started looking into these studies when she didn’t observe any obvious improvements in patients on antidepressants. Larger and more developed trials conducted decades later likewise show such small differences between an antidepressant and a placebo that they do not qualify as a clinically meaningful difference, she says. In 1998, psychologist Irving Kirsch published a widely publicized paper on this phenomenon called “The Emperor's New Drugs.” Psychiatry, she says, hasn’t taken trial results seriously from many decades showing the ineffectiveness of antidepressants: “Why has psychiatry… not said: ‘Oh dear, maybe we should stop giving out these drugs that are having minimal, if any, beneficial effects, and yet are causing side effects, making people dependent, giving people some really severe withdrawal problems, causing sexual dysfunction, making people have falls and bleeds, and causing fetal malformations and all the other things that antidepressants do.”








