Mike Petassi
10 posts
Mike Petassi
@MikePetassi
Postdoc in Greene lab @DNAcurtain @ColumbiaPS \\\ PhD from @JoePetersLab
New York, NY Katılım Aralık 2020
135 Takip Edilen110 Takipçiler
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...And here's another super cool story. 5 new structures showing type I-C Cascade activation, and Acrs can exploit this to shut down adaptive immunity. Movie is apo -> partial R-loop -> complete R-loop -> AcrIF2-bound -> AcrIC4-bound
biorxiv.org/content/10.110…
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Mike Petassi retweetledi
Happy Transposon Day 2022! Today is the 120th birthday of Barbara McClintock, founder of the #transposon field and Nobel laureate. Please celebrate with us by using the hashtag #TransposonDay2022. How has Barbara McClintock or her work influenced you? mobilednajournal.biomedcentral.com
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Mike Petassi retweetledi
Very happy to announce our TnsB paper is out! It includes 2.7 Å cryo-EM structure of transposase bound to transposon end. Wonderful collaboration with @JoePetersLab.
#cryoEM @IIMCB_Poland @Struc_biol_PL @FNP_org_pl
doi.org/10.1016/j.molc…
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Mike Petassi retweetledi
🔥hot off the press 🔥 It's been an exciting few months 😊 Kellogg lab's first paper with @JoePetersLab now out in Science
science.sciencemag.org/content/early/…
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Mike Petassi retweetledi
Happy #TransposonDay2021 from the Peters Lab at Cornell University, Barbara McClintock's training ground!
Mobile DNA@MobDNAjournal
Happy Transposon Day 2021! On June 16 in 1902, Barbara McClintock was born, founder of the #transposon field and Nobel laureate. We, the editors of @MobDNAjournal, are curious to hear how she or her work influenced your career! #TransposonDay2021 mobilednajournal.biomedcentral.com/transposonday2…
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Congrats to @kellogg_liz and co for the first lab pre-print and very happy to be on board! More Tn7-like transposon structure and mechanism to see, this time of the #CRISPR-Cas wielding RNA-guided variety.
Liz Kellogg ❄️🔬@kellogg_liz
The @kellogg_liz lab has posted its first pre-print! Here we continue our mechanistic studies of 'jumping genes' or transposases, in close collaboration with @JoePetersLab on CRISPR-associated transposases ( Type V-K CAST elements). biorxiv.org/content/10.110…
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Excited to be a part of this awesome work from @shen_yao10 and @alba_guarne lab! Finally get to see this piece of the mighty Tn7 transposon!
Alba Guarne@alba_guarne
Incredibly proud of this structure and @shen_yao10 work. I could not have anticipated how much it would explain @j_ortega_McGill @JoePetersLab @McGillMed Structural basis for DNA targeting by the Tn7 transposon biorxiv.org/content/10.110…
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Expanding our understanding of dual-pathway transposition (1 - plasmids; 2 - chromosomal attachment sites) with Tn7-like elements one family at a time. New preprint from bioinformatics wizard @PopoMicro on Tn7-CRISPR-Cas12k
Joseph E. Peters@JoePetersLab
Tn7-CRISPR-Cas12K transposons categorize guide RNAs for different types of integration targets. Previously shown for type I-F3 systems. Grad student @PopoMicro shows an analogous process evolved with Cas12K systems. 1/6 biorxiv.org/content/10.110…
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