Muzumdar Lab

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Muzumdar Lab

Muzumdar Lab

@MuzumdarLab

Studying genetic, environmental, and host factors in tumor progression of #PancreaticCancer and #LungCancer @YaleGenetics @YaleCancer @CancerYale @YaleMed

New Haven, CT Katılım Şubat 2018
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Daniel J Drucker
Daniel J Drucker@DanielJDrucker·
Studies in mice define endocrine-exocrine beta cell-derived CCK signaling as a bona fide driver of #obesity associated PDAC development and uncover avenues to target the endocrine pancreas to subvert exocrine tumorigenesis. #pancreaticcancer nature.com/articles/s4146…
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Müschen Lab
Müschen Lab@MuschenLab·
Beta-catenin promotes cancer cell growth but B-cell leukemia cells, unexpectedly, depend on its efficient degradation. Our paper out today in @naturecancer, shows how this dependency could be leveraged for the benefit of patients with B-ALL.👇 nature.com/articles/s4301…
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UCSC Genome Browser
UCSC Genome Browser@GenomeBrowser·
We recently added a public track hub of "cancer effect size" across 20 TCGA cancer cohorts. Thank you to @JeffTownsend and his lab at Yale University for providing the data. View it on the Genome Browser here: bit.ly/496Cx92.
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Guido Barzaghi
Guido Barzaghi@BarzaghiGuido·
Read the @NatureGenet News&Views me and @artsinyc wrote on the impressive work by @MuzumdarLab and @SStevenWang How does the 3D genome guide Kras-driven cancers evolution? Find out with single-cell genome-wide chromatin tracing! 📖rdcu.be/eShAY
Muzumdar Lab@MuzumdarLab

Excited to share our latest paper in @NatureGenet with @SStevenWang on the evolution of 3D genome organization in 🐁 models of #LungCancer and #PancreaticCancer. Kudos to @Miao__Liu @SherrySu1! @YaleGenetics @YaleCancer @CancerYale nature.com/articles/s4158…

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Yale Cancer Biology Institute
Congrats to poster prize winner, Sherry Agabiti from the @MuzumdarLab for her second place poster titled "Tracing the evolution of single-cell 3D genomes in Kras-driven lung adenocarcinoma". #YCBI
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Muzumdar Lab
Muzumdar Lab@MuzumdarLab·
Great talks and posters from all the labs!
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Nik Joshi
Nik Joshi@Joshilabyale·
We posted this preprint to @biorxiv_immuno that focuses on the idea that CD8 T cells can naturally survey and eliminate stem-cells in the colon epithelium that have neoantigens that are created by somatic mutation. This work was spearheaded by Jess Buck in the lab!
bioRxiv Immunology@biorxiv_immuno

CD8 T cells mediate immunosurveillance for neoantigen+ epithelial stem cells in the colon biorxiv.org/content/10.110… #biorxiv_immuno

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Pavan Bachireddy
Pavan Bachireddy@pbachi·
Thrilled to share our 1st preprint (!) on @biorxiv “Molecular and cellular dynamics of measurable residual disease (#MRD) progression in myelodysplastic syndromes (MDS).” Led by the indefatigable Yu-Hsiang Chen in the lab (x.com/PhRMAfoundatio…). 👉👉biorxiv.org/content/10.110…
PhRMA Foundation@PhRMAfoundation

#PhF25 awardee Yu-Hsiang Chen, a postdoc @MDAndersonNews, is using single-cell technology to study #cancer cells that remain after stem cell transplant. Understanding these cells could help develop better treatments. @pbachi Watch the full interview: phrmafoundation.org/news-events/bl…

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