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NetLab

NetLab

@NetLab14

Network Modelling Research Group @ Koç University #systemsbiology #networks #multiomics #dataintegration

Istanbul/Koc University Katılım Temmuz 2022
35 Takip Edilen83 Takipçiler
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ISCB SC RSG Türkiye
ISCB SC RSG Türkiye@RSGTurkey·
Join us at Open Student Webinar - @kocuniversity to hear from Sina Dadmand (@NetLab14) about oncological drug response prediction with network embedding! 💊 🎟️ Registration: shorturl.at/lpBSW 🗓️ Date: 22nd September ⏰ Time: 13:00 - 16:00 (GMT+3) 📍 Online
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ISCB SC RSG Türkiye
ISCB SC RSG Türkiye@RSGTurkey·
Join us at Open Student Webinar- @kocuniversity to hear from Cansu Demirel (@NetLab14) about network commonalities and differences of cancer and neurodevelopmental disorders! 🧬 🎟️ Registration: shorturl.at/lpBSW 🗓️ Date: 22nd September ⏰ Time: 13:00-16:00(GMT+3) 📍 Online
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ISCB SC RSG Türkiye
ISCB SC RSG Türkiye@RSGTurkey·
Join us at Open Student Webinar - @kocuniversity to hear from Melisa Ece Zeylan about elucidation of important pathways in VCI ! 🩸🧠 🎟️ Registration: tinyurl.com/mr3c8b6v 🗓️ Date: 22nd September ⏰ Time: 13:00 - 16:00 (GMT+3) 📍 Online
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NetLab@NetLab14·
Sina Dadmand and Şeyma Benge Uysal's work on the functional stratification of cancer drugs through integrated network similarity and exploring drug resistance patterns among cell lines, was presented by Sina Dadmand @RECOMBconf conference.
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Nurcan Tuncbag
Nurcan Tuncbag@ntuncbag·
Our new preprint is now online! Bengi (@bengiruken)-Kaan (@KaanariciM)-Cansu (@hcansud) worked together to show that networks of neurodevelopmental disorders and cancer can have shared mutations, proteins, and pathways differing in mechanisms, signaling strength, and outcomes.
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bioRxiv SysBio@biorxiv_sysbio

Neurodevelopmental disorders and cancer networks share pathways; but differ in mechanisms, signaling strength, and outcome biorxiv.org/cgi/content/sh… #biorxiv_sysbio

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NetLab@NetLab14·
Congrats to Bengi Ruken Yavuz on her paper. She have recently presented this work as a poster at RECOMB-CCB sattelite meeting.
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NetLab@NetLab14·
Despite cancer-wide existence of a set of driver genes, having double mutations in those genes is cancer type specific.
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NetLab@NetLab14·
Cancer latent drivers can additively intensify the signal when coupled with other activating mutations. They have low frequency and escape idenfication. In this study, we explored the potential impact of “latent drivers” on cancer progression and cataloged 155 latent drivers.
Communications Biology@CommsBio

@bengiruken, @ntuncbag et al use a statistical methodology to identify potential latent driver mutations from public cancer bulk sequencing data. @NetLab14 nature.com/articles/s4200…

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Molecular Omics
Molecular Omics@MolecularOmics·
🎉Rounding out this first week of our Emerging Investigators highlights is Nurcan Tuncbag @ntuncbag with this excellent review on multi-omics computational approaches and their clinical applications! Read it in full below 🔽 pubs.rsc.org/en/content/art…
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NetLab@NetLab14·
@KaanariciM has presented his method called PageRank-flux on graphlet-guided-network method(PRO-GGNet) for pathway reconstruction & multi-omic data integration.
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NetLab@NetLab14·
Yıldız Aydın has presented her work on interaction of SMN with microtubule-associated proteins by network analysis.
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NetLab@NetLab14·
We have participated to @HBioinformatics with whole Network Modelling Lab! For details on our presented posters: ++
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Keşfet

@kocuniversity @KaanariciM @RECOMBconf @bengiruken @hcansud @ntuncbag @sina_dadmand @NozluLab