Neuert Lab

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Neuert Lab

Neuert Lab

@NeuertL

PI at @VanderbiltU @VUBasicSciences @VanderbiltMPB focusing on Quantitative Systems Biology of Dynamic Signal Transduction and @GeneRegulation in Single Cells.

Vanderbilt University Katılım Aralık 2016
93 Takip Edilen135 Takipçiler
Neuert Lab
Neuert Lab@NeuertL·
Transcriptional stochasticity enables the Xist–Tsix locus to switch between lncRNA control modes. Medium transcription lays H3K36me3 to curb Xist; high transcription triggers polymerase interference. Variability isn't noise—it’s regulation! #lncRNA #XCI nature.com/articles/s4146…
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Nature Reviews Bioengineering
Nature Reviews Bioengineering@natrevbioeng·
The drug development pipeline is costly and inefficient. In their new Comment, C. Leasure & G. Neuert argue that the effects of pharmacokinetic drug profiles on cellular behaviour should be tested in vitro earlier in drug development! @NeuertL @VanderbiltU go.nature.com/4bv2lvW
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Neuert Lab
Neuert Lab@NeuertL·
Just because the concentration of stimuli changes doesn't mean cells respond in the same way. @AlexThiemicke & @NeuertL review on cell sensitivity to environmental rate changes reveals a widespread and underappreciated fundamental property of cell signaling - rate thresholds.
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Ken Lau Lab
Ken Lau Lab@KenLauLab·
Our latest preprint constructs phylogeographic maps of tumor evolution, tracking clonal and microenv changes along progression pseudotime. Excited to share this atlas as a rich resource for spatial analysis of human CRC! Grad Student- @cody_heiser doi.org/10.1101/2023.0…
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