Rune Nguyen Rasmussen

307 posts

Rune Nguyen Rasmussen

@NeuroRune

PhD in neuroscience | MSc in human biology | BSc in sport and exercise sciences

Copenhagen, Denmark Katılım Temmuz 2016

519 Takip Edilen485 Takipçiler

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Rune Nguyen Rasmussen@NeuroRune·7 May

🚨 Preprint alert 🚨 - Thrilled to share our latest computational work entitled: "Local changes in potassium ions modulate dendritic integration" by @Malthe_nord et al. 🧠💻 Truly fun collaboration with @na0ya_takahashi and @NassiPapoutsi. Check it out! biorxiv.org/content/10.110…

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Naoya Takahashi@na0ya_takahashi·13 Kas

Pls RT! We're hiring! My lab @iins_bordeaux seeks postdocs and PhD students to study cortical processing underlying touch and embodiment using in vivo imaging and Neuropixels. Positions funded by @CercleFSER, @FRM_officiel, @AgenceRecherche. Details👉 fens.org/careers/job-ma…

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Jared Cregg@j_cregg·5 Şub

Join us in Copenhagen April 15th-19th for a PhD course on open neurophysiology. Nordic PhD students can attend tuition free!

Søren Grubb@SorenGrubb

🧠✨ For PhD students of Copenhagen and beyond: Dive into the world of open neurophysiology with our exclusive PhD course from 15-19 April 2024 @UCPH_health! Uncover the potential of open datasets and tools in neuroscience: phdcourses.ku.dk/DetailKursus.a… #OpenNeurophysiology 🧵

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Peter Petersen@petersenpeter·5 Şub

Are you a PhD student in Copenhagen/Denmark looking to learn more about all the new open tools and datasets coming out? Join us for an exciting week of open science, open-source tools, and playing with open neuroscience data.

Søren Grubb@SorenGrubb

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Rune Nguyen Rasmussen@NeuroRune·19 Tem

@icanhasMiranda @MedicalCollege Fantastic news!! Congratulations Miranda – they're very lucky to have you! Looking much forward to follow your lab in the future :)

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Rune Nguyen Rasmussen@NeuroRune·1 Tem

@roaldarbol @DFF_raad @VILLUMFONDEN Jeg forstår din frustration Mikkel. En mulighed, omend også projekt-baseret, kunne være at søge @lundbeckfonden's LF Experiment som gives til risikable 2-årige forskningsprojekter.

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Rune Nguyen Rasmussen@NeuroRune·30 Haz

@AnnaIntegrated Very cool! What's the signaling cues here?

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Anna Vlasits@AnnaIntegrated·30 Haz

Waves!

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Rune Nguyen Rasmussen@NeuroRune·20 May

@suprajagv @UTSWNeurosci @UTSWBrain You’re most welcome. Looking forward to following your lab from the “sideline” 🤓

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Supraja Varadarajan@suprajagv·20 May

@NeuroRune @UTSWNeurosci @UTSWBrain Thank you Rune!!

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Supraja Varadarajan@suprajagv·19 May

I am absolutely thrilled and honored to announce that I will be joining @UTSWNeurosci and @UTSWBrain as an Assistant Professor in January 2024!! My lab will investigate the mechanisms underlying neuronal activity-induced repair with a focus on vision restoration. 🐭👁️🧠🔬

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Rune Nguyen Rasmussen@NeuroRune·18 May

@hubermanlab @SusannaSberg1 Excellent podcast – I may test the waters around Copenhagen harbour come winter time🥶 One comment: I think the diving reflex is elicited when receptors within the nostrils and face are exposed to cold water and is amplified by breath-holding; that is, head needs to be submerged.

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Andrew D. Huberman, Ph.D.@hubermanlab·15 May

New Huberman Lab Podcast out now: How to Use Cold & Heat Exposure to Improve Your Health w/Dr. @SusannaSberg1 •Cold for Metabolism •Best Cold/Heat Protocols •Modern Cold/Heat Science Made Clear •Treating Illnesses •Hormone & Dopamine Effects hubermanlab.com/dr-susanna-sob…

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Rune Nguyen Rasmussen@NeuroRune·16 May

🚨Cover alert🚨 Very glad to see our illustration of astrocyte calcium signaling featured on the cover of @TrendsNeuro. Big kudos to Antonis Asiminas (@temp2spec) for drawing this one🎨

Trends in Neurosciences@TrendsNeuro

June 2023 issue of @TrendsNeuro: cell.com/issue/S0166-22… Free featured content & more: cell.com/trends/neurosc… On the cover: ‘Astrocytes: integrators of arousal state and sensory context’ by R. Rasmussen @NeuroRune, Antonis Asiminas, @Eva_Carlsen, @CeliaKjaerby & @NathanASmith1

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Rune Nguyen Rasmussen@NeuroRune·10 May

@LoogerL @yulonglilab No, I have not personally used. We will look into the sensors by Robert Campbell and see what is doable for us in the future. Thanks again!!

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LoogerLab@LoogerL·10 May

@NeuroRune @yulonglilab have you tried the existing sensors, mostly from Robert Campbell?

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Rune Nguyen Rasmussen@NeuroRune·7 May

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Rune Nguyen Rasmussen@NeuroRune·10 May

@LoogerL @yulonglilab Interesting. We do think it’s reasonable to expect increases of at least 1-2 mM near dendritic segments with functional clusters (with all limitations of course giving uncertainty). Segments with diverse tuning we expect 0.25-1 mM changes. Let’s see!

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LoogerLab@LoogerL·10 May

@NeuroRune @yulonglilab Well, if you're really getting 0.5 to 5 mM changes, even a linear sensor would pick that up. But if you're getting that huge change, then presumably you'd see it reflected in voltage, Ca2+, etc? Ppl usually ask about seeing more subtle changes

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Rune Nguyen Rasmussen@NeuroRune·10 May

@LoogerL @yulonglilab Ah I see. That makes sense. I guess, for now, we have to make due with computational work in combination with ion-selective microelectrodes for probing changes within the physiological range (0.5-5 mM). Thanks!!

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LoogerLab@LoogerL·10 May

@NeuroRune @yulonglilab manner, i.e. "a calmodulin for K+." No such known proteins exist and will need to be de novo designed. Without such proteins, I think K+ sensors will be essentially useless.

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Rune Nguyen Rasmussen@NeuroRune·10 May

@LoogerL and @yulonglilab: Any plans of trying to generate a high-sensitivity genetically-encoded extracellular potassium ion sensor? ;)

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Rune Nguyen Rasmussen@NeuroRune·7 May

Finally, thanks to all funding agencies, including @lundbeckfonden, @DFF_raad, and @novonordiskfond.

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Keisuke Yonehara@KeisukeYonehara·9 May

I am hiring a postdoc in neurophysiology for a vision restoration project in Aarhus, Denmark. health.au.dk/en/about-healt…

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Rune Nguyen Rasmussen@NeuroRune·8 May

@ptrrupprecht @Malthe_nord @na0ya_takahashi @NassiPapoutsi @ValentinNagerl That would indeed be very exciting to obtain such experimental data, although very challenging as you also point out. I guess the most fundamental aspect to test first is our prediction of dendritic [K+]o hotspots during co-active inputs; ideally with absolute mM resolution.

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Peter Rupprecht@ptrrupprecht·8 May

@NeuroRune @Malthe_nord @na0ya_takahashi @NassiPapoutsi @ValentinNagerl Maybe this would even allow to combine in vivo activity measurements with extacellular space measurements ... but for sure not something that can be done quickly!

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Rune Nguyen Rasmussen@NeuroRune·8 May

@ptrrupprecht @Malthe_nord @na0ya_takahashi @NassiPapoutsi So if you had differences in ECS space across dendritic segments, everything else being equal, you would theoretically have different K+ change amplitudes which could have notable effects on local gain (high vs low) of synaptic inputs. Do you know of such ECS data?

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Rune Nguyen Rasmussen@NeuroRune·8 May

@ptrrupprecht @Malthe_nord @na0ya_takahashi @NassiPapoutsi Thanks Peter! Re R_2, that is indeed interesting. As we allude to in the paper, we do not have specific data for the ECS space around specific dendritic segments, so we treated all segments equal. But the size does have a substantial effect for the K+ changes - see Figure 1G:

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Keşfet

@iins_bordeaux @CercleFSER @FRM_officiel @AgenceRecherche @icanhasMiranda @MedicalCollege @roaldarbol @DFF_raad