NEURON-Percepta

Treating neuroinflammatory disease with galectin-3 inhibitors from our GALE project has come one step closer with the discovery of a blood-brain-barrier permeable Galectin-3 inhibitor through AI and animal models by a team from the Fujian Medical University, Fuzhou, China. They demonstrated clear pharmacological and clinically relevant effects in a widely used Alzheimer's Disease model, despite the low potency and limited brain exposure. This is a strong signal ahead of our own experiments.

Brain health is entering its utility phase. 📱 Cortex gives you a Brain Health Score you can track over time – a baseline that you can re-assess to measure and improve your cognitive wellbeing. 🧠 Cognition connects you to @Neuron_Percepta and other research-backed products and interventions curated by our team. Measure your brain. Act on what you learn. Improve your brain health. This is the loop we're building.

Dr. Alan Snow is presenting new data at AD/PD 2026 in Copenhagen this week, comparing Percepta against the top-selling memory supplements on the market for their ability to target brain plaques and tangles. This study builds on his 2021 study published in Nature Scientific Reports, where Percepta outperformed 20+ major supplements, including Prevagen, Neuriva, and Alpha Brain, in disaggregating beta-amyloid fibrils and tau tangles in vitro. The new results, yet to be published, replicate those findings – Percepta was again the most effective at reducing both amyloid fibrils and tau tangles across all doses tested, outperforming every major competitor. Most brain health supplements have never been tested this robustly. Read the original 2021 study: nature.com/articles/s4159…

Brain health – so important, yet so tough to define and measure. Cortex will finally change that. Take a survey, access your score, and track change over time. We've been measuring steps and HR for years. It's time the brain caught up. cerebrumdao.com/cortex-app

Our onboarding flow and functionality for Phase 0 of Cortex.🧠🚀 Get early access here: cerebrumdao.com/cortex-app

We are very excited to say Phase 0 of our Cortex app is imminent! ⚡ Current sign-ups will be sent instructions in the next few days. You can join the 1,000+ who have already signed up for early access here: cerebrumdao.com/cortex-app Stay tuned for more release information.

We are putting the last details into place for our decentralized clinical trial. Pursuing a human trial for a desci-funded brain health supplement is hugely exciting and shows how people's investments genuinely connect to the outcome. View here: molecule.xyz/ipts/claw

457 compounds screened. Results incoming. Once we have the data back from this large-scale experiment, the team will run dose response testing to measure which hits are the most potent. That puts us at a genuine inflection point for the Fission Bio program. The next few weeks matter. Of course, we are hopeful @Cerebrum_DAO @Molecule_sci.

We got to a place with heart health where you can measure it, understand risk, and intervene. That took decades of research and commitment. Brain health is more complex. We're still early. But we will get there. That's what we're here for. The next frontier in human health.

The @Neuron_Percepta trial is fully decentralized. How it works: → Participants recruited remotely, products shipped directly to them → Wearable sensors track sleep, HRV, and activity continuously → At-home blood collection for P-tau 217 biomarker tracking → Cognitive assessments administered through dedicated trial software The result is a depth of data that conventional trial structures simply can't match, paired with the ability to reach participants wherever they are. View the project and track the results @molecule_DeSci: discovery.molecule.xyz/labs/cerebrum

How the Percepta project moved from its promising early research to tokenization as $CLAW, securing funding for the decentralized trial that recently received IRB approval. This is a true example of how DeSci accelerates science and gives everyone a stake in a real outcome.

‼️The Cognition Store launches imminently. Brain health science backed by community capital, validated through research, available to all.

Inside our @Neuron_Percepta trial. We're tracking p-Tau 217 through at-home blood collection, running neurocognitive assessments, and integrating wearable monitoring for sleep, HRV, and activity. All within a 6-month, double-blind, decentralized, randomized placebo-controlled design with IRB approval secured

We are now trackable on @Molecule_sci's Labs platform – from IRB approval to biomarker integration, every milestone will be published here. This advancement will help us tighten operations around what is probably the most ambitious decentralized clinical trial in brain health right now.

We’re excited to see the continued evolution of the Molecule ecosystem. From day one, Molecule has pushed the boundaries of bringing scientific IP and funding onchain, and now with Labs, they’re taking researcher tooling and scalability to the next level. At Cerebrum DAO, our mission has always been to accelerate decentralized science in neuroscience and longevity. Having access to integrated tooling that supports: - Research data management - Milestone tracking - Transparent fundraising - AI integrations - Contributor and permissions management We’re proud to be part of the beta alongside @vitadao and to collaborate closely with Molecule as we continue building. The next phase of decentralized science is about coordination, transparency, and scalable infrastructure. This is exactly the direction we need. Access it here: discovery.molecule.xyz/labs/cerebrum

@0xsimmo @Molecule_sci You can read anecdotal testimonials on Amazon or on Perceptabrain.com. As for the higher-end outcome, we can only await the trial results for now. In-vivo findings have previously been impressive.

@Neuron_Percepta @Molecule_sci What does this drug do anacdotally for oral takers? What would be the higher end outcome from human trials if the drug performs.well?

‼️Percepta is moving from the lab to human trials. Clinical approval submitted, at-home testing tech validated, study ready to launch. Human data is next. The full update is live on @molecule_sci -> molecule.xyz/ipts/claw/upda…

Read the @FissionBioDeSci and $MITY story - we're anticipating some more results very soon!

Our @Neuron_Percepta trial illustrates how DeSci can decouple from market dynamics to deliver real-world, high-value outcomes. Every 3 seconds, someone develops dementia. By 2050, that's 139 million people and counting facing Alzheimer's or related conditions. Pharma takes 10-15 years and billions to move a drug through development. We raised $500K from 115 people in months, secured IRB approval, and launched trials tracking cognitive performance and biomarkers. We keep pushing forward on the diseases that affect millions.