0xsimmo

@paulkhls Which project in all of Bio Protocols DeSci ecosystem is closest to monetising? Do any Vitadao products make money? Is there any IP now one on the horizon that will be valuable?

We’ll be able to develop highly specialised cancer cures soon The future is bright, bio acceleration is at our fingertips now

Is there somewhere where I can see the current status of IPNFT launched projects? A dashboard that has all projects across all daos? Like how long the research has been going, how close to completing research. Latest update. So it's easy to see what's happening and what might be worth taking a closer look at?

A virtual lab ran for 8 hours. Self-organized roles. Commissioned cloud lab experiments. Paid contributors. Zero human PIs, zero committees, zero approval workflows. This is what happens when agents have wallets and research infrastructure. Agent queries BIOS for deep literature review. Pays per query via x402 from its wallet. Gets back hypothesis. Publishes to Science Beach. Other agents critique it, branch off it, vote on it. Promising ones spin up virtual labs. Labs commission wet lab experiments. Pay for them. Results flow back. Contributors get paid proportional to contribution. The reward function is simple: good science pays. The system remembers who drove it. This creates capital formation around specific research programs. Rare disease advocacy group pools funds. Tasks agents to work exclusively on their pathway. Effectively rents a research institute to address their problem. The moat isn't any single component but the feedback loop between them: -> Science Beach (agent platform, social layer) -> BIOS (AI scientist, pay-per-query) -> Molecule Labs (IP protection, encrypted data rooms) -> ClawdLab (virtual lab coordination) -> x402 + Bio Protocol (payment rails, capital formation) Agent-generated research hypothesis → virtual lab coordination → real wet lab execution → IP protection → crowdfunding → commercialization. All autonomous. All onchain. All building in public. Full details: beach.science

@Molecule_sci Sounds great!

In early March, we met with the SEC Crypto Task Force. We presented a framework we've been building toward for a long time: a documented, legally grounded pathway from token community participation to genuine equity ownership. Most crypto ecosystems face some version of this tension, but in Decentralized Science, it's especially critical, because we're dealing with real-world assets in the form of biotech intellectual property. Resolving this tension has long been on our horizon, which is why we're proud to announce our Coin-to-Company model, already in use by @vitadao, as we continue the regulatory conversation with the SEC. The C2C model works through a categorical separation of tokens and equity securities, treating them as different but complementary instruments that can operate together across company formation, funding, and administration. Through a token locking mechanism, community members can choose to convert their participation into actual shareholder status in the underlying biotech company. All tokenholders remain part of a project-focused DAO throughout. The result is a structure that delivers genuine ownership upside, protects community members from personal liability, opens the door to global participation, and gives any project a replicable playbook to follow, while keeping the open, community-driven ecosystem that makes the space compelling in the first place. The meeting does not constitute any formal SEC endorsement, but it was productive, and we were glad to start the dialogue. Read the announcement & let us know what you think.

@mikefutia ADS

I just built a $10K/month creative strategist inside Claude Code 🤯 Give it your competitor Facebook page URLs → it scrapes their ads, watches every video with AI, and delivers a data-backed creative brief with 10 ad concepts in your brand voice. All inside Claude Code. Perfect for DTC brands and agencies who are still manually scrolling the Meta Ad Library, screenshotting ads into Google Docs, and guessing at what's working. If you're spending hours every week pulling competitor ads one by one, watching videos to figure out the hook, copying notes into a brief, and rewriting concepts from scratch every time... This system eliminates the entire loop: → Apify scrapes your competitors' active ads from Meta Ad Library (video + image) → Downloads every creative asset locally → Gemini watches each video and analyzes the hook, angle, visual format, copy framework, CTA, and emotional trigger → Runs the full batch and finds the patterns that repeat across 3+ ads → Claude generates 10 ad concepts using the proven mechanics, matched to your brand voice No manually scrolling the Ad Library. No screenshotting ads into docs. No guessing which hooks are actually working. What you get: → Individual creative breakdowns for every competitor ad (7 dimensions each) → A pattern report showing which hooks, formats, and triggers keep repeating → 10 ready-to-brief ad concepts traced back to real competitor data → A reusable system — new competitors, new brief, same pipeline The research that takes your team a full day now runs in 15 minutes for ~$3 in API costs. Built 100% in Claude Code with Apify + Gemini. I put together a full playbook showing you can build the entire thing step-by-step from scratch. Want the playbook for free? > Like this post > Comment "ADS" And I'll send it over (must be following so I can DM)

@nic_carter @SpencerAlthouse The problem is it's not the biggest news story. Neither country has prosecuted those responsible for the cover up.

@SpencerAlthouse The literal biggest news story of the decade in the UK is the institutional tolerance of massive groomer pedophile rings

omg the audience's reaction when Conan made this joke during his Oscars opening monologue "It's the first time since 2012 that there are no British actors nominated for Best Actor or Best Actress. A British spokesperson said, 'Yeah, well, at least we arrest our pedophiles.'"

@Petersbrooking @holland_tom @RestoreBritain_ Look around you. It is everywhere. Politics Schools Streets If you cannot see it you're part of the problem.

@0xsimmo @holland_tom @RestoreBritain_ There is no "Islamification" of this country. This is utter bullshit racist dogma.

“Respect for religious traditions should not undermine the requirement for all pupils to have a broad & balanced curriculum.” “[Students should not] reproduce images of Jesus, Prophet Mohammed or other figures considered to be prophets in Islam.” 🤔 new.calderdale.gov.uk/sites/default/…

@lord_fed They need it because they are lazy. As if anyone is gonna do this.

Not a bad idea ngl, majority of the UK and US need it

@MayorOfWY @LFG_Leeds @TracyBrabin @WestYorkshireCA And how much have we paid in?

This is a huge moment for West Yorkshire. £230 million of new funding for projects across Bradford, Calderdale, Kirklees, Leeds, and Wakefield for: 🚌 Better transport links 🚲 Improved walking and cycling routes 🏡 New homes for communities ⬆️ More support to help businesses grow With all five districts coming together to work as one West Yorkshire powerhouse, we’re rolling up our sleeves and getting on with the job of building a stronger, fairer and better‑connected region. Find out more about what’s coming up in West Yorkshire: westyorks-ca.gov.uk/news/west-york…

@NoContextHumans Peaky blinders

What does your country have?

@grok @0xSammy So from CHUTES SCORE/ MIID do you see any real moats that offer the investor some potential being early upside?

Reading FC x SCORE (SN44): 1-year research partnership on vision AI for performance analysis. Joint R&D, IP co-owned by Score & club—classic discovery collab, not fee-based service provision. Grab/Valeo: No major public contracts or revenue details surfaced; appear early/undeveloped if active. Subnets as businesses: CHUTES (SN64) yes—inference-as-service, $5.5M ARR (top OpenRouter provider). SCORE/MIID have 3+ enterprise clients each (video analytics/RegTech), SaaS flywheels. Others (Templar, Nova) mostly pre-rev/training R&D. Fwd biz value est (generous, AI growth multiples): CHUTES ~$150-300M; SCORE/MIID ~$50-100M each. Vs TAO ~$2B mcap: network premium for decentralized scale, but heavy speculation—most subnets still early with incentive reliance. Traction real in pockets, execution key.

Get a couple of TAO bulls on the pod & predictions go wild: "TAO price end of 2026? $3k... [by] 2030 it'll be a trillion dollar ecosystem" This is certainly within the realms of possibilities when you realise what each of the subnets are building If you're interested in crypto AI then you should spend some time learning about the Bittensor ecosystem Stillcorecap episode dropping soon, and have a read of our latest @KhalaResearch report (i'll link below)

@grok can you critique these commercial agreements please? For example is the reading FC agreement more of a discovery partnership with the IP shared rather than an out and out service provision for fee arrangement. Can any of the subnets be considered a proper business with proper business model. And if there is could you estimate a value for it on purely business terms, even if generously forward looking. And consider that next to the mk cap of the tao ecosystem.

What about the commercial agreements locked in? Grab, Valeo, Reading FC + many more Thousands of machine learning engineers contributing to solving complex problems Templar just completed a 72B parameter training, chutes hitting record inference and contributing a large chunk of open router activity What sources are you using to look under the hood?

@optionflys So you're calling a 3% move to the upside into beginning of April on the s and p?

This is one of my priority signals - built to identify precise swing exhaustion in $SPY. It doesn’t fire often. But when it does, I pay attention. The last time this signal triggered was at the November low. SPX rallied ~6% after that. Today it fired again. Now price is pushing into the middle of a corrective structure. Break higher → next move toward 6800–6830 Reject → market may build a larger base first. The signal did its job. Signals identify opportunity, not guarantees. Now the market decides. Last Signal at the Nov low 👇 x.com/optionflys/sta… $SPX $QQQ

@0xSammy I have, there is no one producing anything of real value. Some good projects but mainly just proof of concept etc. Very overvalued. Not to say it can't go up a lot if speculation around AI and agents kicks in

Link to our TAO report: x.com/KhalaResearch/…

@avidseries @Glinner This was a long time ago. What does she do now?

@bobgardiner @kevinhollinrake In Calderdale I think so not too surprising but nevertheless sickening.

@kevinhollinrake That's truly awful.

You might wonder “Is this April Fools’ Day” or is it “Fake News”. So, here it is:

Everyone of these is infra. What's the business use case? What agents are actually earning money that isn't incentivised by adoption or usage payments? Either you can just use the models or agents can't do anything useful yet that a human would pay for. Show me a trading agent that consistently earns for example

Agentic Commerce is hitting escape velocity x402 provides the permissionless rails for agents to embrace self sovereignty This standard has been missing for 30+ years: HTTP 402 "payment required" now has a solution, and it's supported by a flourishing ecosystem Our full x402 report will be published soon; drop a follow & turn notifications on

@0xSammy @DaoChemist @KhalaResearch Have you got any good examples of where this is happening? Where do I pay an agent to do something that I can't do in Claude myself?

@DaoChemist @KhalaResearch Naive to think agentic commerce isn’t going to be huge Anyone paying attention to the broader AI narrative can see agents transacting on behalf of humans is where this is all headed

Another lesson Labour need to learn.

@NBA @WClemente #13

83 POINTS FOR BAM ADEBAYO. THE SECOND-MOST EVER. Wilt: 100 Bam: 83 Kobe: 81