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“It is difficult to get a person to understand something when their salary [or identity] depends on their not understanding it.” … Upton Sinclair [Me]
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Nick Eggleton
34.4K posts
Nick Eggleton
@NickEggleton
Marketer/Health Coach/Husband/Dad/Golf/ALAW/🥩 Open-minded, curious & skeptical. Does Not Comply.
Perth, Western Australia Katılım Ocak 2009
855 Takip Edilen2.2K Takipçiler
lol.
I muted you.
Think you were ranting about something.
Re 'Capitalism' It's not meant to 'solve' poverty. And.
Capitalism isn't the antithesis of socialism.
And.
Socialism isn't meant to solve poverty either.
I reposted this bc the point of socialism is to keep people believing the source of their oppression/inequality is someone else's fault and that someone else will save them if only they stay with the plan.
The cartoon illustrates how they should 'behave': keeping climbing the victim ladder while socialist government keep letting the rope out so they never reach 'utopia.
Nice to see you've dropped the Ukraine flag from your Bio.
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@NickEggleton @BasedMikeLee No. I can see what you post. No mute or block from me.
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Nick Eggleton retweetledi
@BasedMikeLee @NickEggleton Not defending socialism at all but when and where did capitalism solve poverty?
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Prophetic?
No. She knew who the general public's enemy was, it was her enemy.
'Give them an inch and they'll take a mile,' is never 'Give us an inch and we'll give you a mile. '
Fabian's/Socialist control come from false promises of Utopia where the takers win and the givers lose.
Fuck socialism.
Margaret Thatcher@realmrsthatcher
Freedom can also be lost little by little, by what the Fabians call the doctrine of gradualness. A little more taxation here, a little more government expenditure there, year after year until the people are no longer the masters of the state but its servants. There are always, it seems, good reasons advanced for the state to have more power. But rarely for the state to divest itself of power. Each new problem becomes an excuse for more government intervention and less individual responsibility.
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Two brilliant minds together talking, "How and why Insulin Resistance drives chronic disease" with Dr. Isabella Cooper and Dr. Zoe Harcombe, Bravo! @zoeharcombe #healthcoach #insulin @I_mitochondria
zoeharcombe.com/2026/03/dr-isa…
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@craigkellyAFEE They certainly were useful to the Islamicist revolutionaries during the Iranian 'Colour' Revolution of the 1979. Until they weren't. How do 'socialist activists' not know this. It's only 47 years ago. Bernie was around then.
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Perhaps Albanese should have read my post from yesterday.
Leftist’s are the "useful idiots" of radical Islam.
Whether or not enough leftists wake up to that fact quickly, depends upon whether or not Western Civilisation survives.
Craig Kelly:🇦🇺Foundation for Economic Education@craigkellyAFEE
The partnership between far left and Islamists is the greatest ever threat to Western Civilisation. Tragically, the far left are too stupid to understand that if the Islamists take over, they’ll be the first ones they come after.
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There is remarkably little sugar in your blood ONLY ONE TEASPOON of glucose in your entire bloodstream!! This is why small amounts of carbohydrates put blood sugar up so much if you have T2 Diabetes where insulin is not working properly @CampbellMurdoch I think you gave me this slide 🙏
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Hi Penelope
I'm afraid this conversation is almost 6 years old. And I think the evidence is now clearer. However, I'm having trouble following the thread bc I blocked most people in it at some time in that time. But I still believe in N = 1. And a paradox disproves a hypothesis. That is the scientific method 101. Complex systems are loaded with undiscovered black swans.
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@NickEggleton @MacroFour @TerryExSci @FoodFirst_Ty @neighborchick @JesseLunsford That will be a “ paradox” though won’t it, the black swan!
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Nothing bad. That’s the true answer. Maybe some lower LDL. Maybe some better BMs. Not whatever bullshit this clown is trying to sell you. Stay away from quacks kids.
Ken D Berry MD@KenDBerryMD
What will happen if you eat OATS every day?? Then answers might surprise you! WATCH: youtu.be/bzXqoY7SKcw
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Quoting Richard Feynman is ironic. He also said,
"The first principle is that you must not fool yourself—and you are the easiest person to fool"
N-6 : N-3 ratio isn't even the issue with these industrial synthetic Frankenstein oils. It's the quantity people consume them.
But even if it were an issue people consume too much n-6 overall from many sources. The SAD diet ranges from 12:1 to 20:1 n-6:n-3. In volumes that are evolutionarily supra physical doses. Please do not defend Canola.
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The post below is a great example of something Richard Feynman famously talked about: knowing the name of something, versus truly understanding it.
There are many so-called "seed oils" (also often called "vegetable oils").
They share the same linguistic designation, as they share certain things in common, including the part of plants they're derived from and overall fatty acid content compared to other oils.
"Seed oils" as a group nonetheless vary widely from one another in terms of their specific fatty acid profile.
The n-6 PUFA content of seed oils is what "anti-seed oil" people point to as the bad thing. Linoleic acid is the major n-6 PUFA in seed oils.
So, the "ultimate seed oil" would be a bottle of pure linoleic acid. But real-world seed oils aren't pure linoleic acid, they're different mixtures of various fatty acids.
Sunflower oil, for example, as VERY high n-6 PUFA content, even more than other seed oils, with almost no n-3 PUFA and low MUFA content.
In contrast, canola oil as MUCH lower n-6 PUFA content, with some n-3 PUFA content and much more MUFA content.
In fact, canola tends to have more MUFA than it does n-6 PUFA, by quite a bit. In other words, compared to other seed oils like sunflower oil, canola has one of the lowest n-6 PUFA profiles.
Take a look:
Oliver Venture@_OliverVenture
“Akshully seed oils are good,” Canola is famously a seed oil. (Presents data confirming canola is very good) Of course it's annoying that we have to pretend that context doesn't matter. Which is we hope people are replacing sfas with seed oils. Because replacing sfa with sunflower oil slightly lowers crp and cvd. And replacing sunflower with canola lowers crp and cvd. Canola and olive oil have the same crp and cvd benefits (perhaps different pathways). But canola has more LA than olive. Canola has less sfa than sunflower. Canola has more omega-3 than sunflower. So presumably if we were actually worried about sunflower or somehow canola then we'd be very worried about sfas.
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@natureboyrr Lefty's in the 10% Club.
Jibby Babby averse 15% (ish).
AB R-ve 1%
So statistically speaking I'm a freak.
Would be interesting if more than 10% of unjabbed are left handed.
But more than 10% of top test cricketers and architects are. So some cohorts...
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I do wonder if the percentage of left-handers not being jabby jabbed was significantly higher than right handers.
Don’t get me wrong. Some GIGANTIC Aholes lefty. And some super holistic real deal righties, my wife one. But in large numbers I wonder. Right mind and all.
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Dave actually says, 'We have already taken steps regarding last year's paper that contained the original Cleerly analysis. We are working with the journal on that now, and we expect news on this very soon.'
I don't think there is anything wrong with highlighting inconsistency and alerting ppl to steps being taken.
Calling for 'retraction' on a post pre-empting a revision is a little niggly, no?
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Ok, I misread the published v preprint part. That is a basic fact, but doesn't make my comments any less valuable.
Dave actually says, 'We have already taken steps regarding last year's paper that contained the original Cleerly analysis. We are working with the journal on that now, and we expect news on this very soon.'
I was questioning your additional call to retract in light of that, and the facts that Cleerly are 'owned' by Novartis, and they provided the data to make it look weaker than it should've been. The implication of a call to retract being the conclusions are incorrect: 'Importantly, the two principal findings reported in the original paper have been reproduced in both the Heartflow and QAngio analyses:
(1) baseline plaque strongly predicts future plaque progression, and
(2) ApoB was not associated with plaque progression.'
'An update with stronger data would be valuable'. That's what you could've said.
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Sounds like a retraction of the original paper is in order.
Dave Feldman@realDaveFeldman
I want to share a crucial update on our study, KETO-CTA. (The video for this article is in the next tweet) Our study recruited 100 participants, each undergoing two high-resolution heart scans, known as CT angiograms, one year apart. (For more background on this study design, see preprint in the following tweet) There are now four analyses of those same 200 scans. But one of those analyses stands out — and I have some new developments to report. For a quick background, the first quantitative analysis was from an AI company, Cleerly. We published their analysis of our scans last year. After the paper was published, the Citizen Science Foundation was free to look at the raw Cleerly data, and we found a number of patterns that appeared different from what is typically seen in other coronary plaque studies. For example, in Cleerly's analysis, not one of the participants showed lower plaque levels at follow-up — even though CTA scans typically show some natural variation in both directions, especially in people who start with very little plaque. For another example within their data, people with no detectable calcium in their scans appeared to have several times more plaque progression than those who already had some calcium present. This runs counter to what many in cardiology call the "power of zero" — the well-established finding that having no coronary calcium is typically associated with lower risk and slower disease progression. Another major development: shortly after publication, we learned that the scans Cleerly was analyzing were not fully blinded. In studies like this, the order of scans is typically kept unknown to the analyst to help prevent any potential for bias. But in this case, the chronological order was available in the scans. We therefore asked Cleerly to repeat their analysis using a properly blinded set of scans, which is standard practice in longitudinal studies. Cleerly declined to perform a blinded reanalysis. Because of this, we commissioned an additional, independent analysis from Heartflow. Heartflow has been a leader in this space and is the most extensively validated AI platform for coronary CTA analysis. The Heartflow analysis was conducted with full operational blinding and completed right before the prespecified third, and final quantitative analysis, which uses Medis QAngio. These two independent platforms were consistent with each other, yet both differed substantially from the Cleerly results. As these independent results became available, we shared them privately with Cleerly and again requested a blinded reanalysis of their original work. We offered to cover any costs involved just in case this was the barrier to reanalysis. Cleerly again declined. However, a new development emerged. Several participants requested their scans from the study and submitted them directly through their own, personal cardiologist. Any cardiologist with a proper Cleerly account can appropriately submit scans on their patient's behalf. So in a sense, our participants themselves were able to provide a portion of the blinded analysis we were originally requesting. This was then shared with me on behalf of the Citizen Science Foundation. In total, there are 19 of these individual submissions — about 10% of the total scans in our study so far. Individual Submissions vs. Study Data We focused on the 8 participants who have both a baseline and a follow-up individual submission of their scans (the other 3 submissions are unpaired). [Please Note: These data are preliminary] Figure 1 compares the change in soft plaque (Non-Calcified Plaque Volume or NCPV) reported by the original Cleerly study analysis against the results from each participant's individual submission. [See Figure 1] Of the 8 participants, four showed an increase in soft plaque in both datasets — but in three of those four cases, the individual submissions reported substantially less progression than the study data. The remaining four participants all showed progression in the study data, yet every one of their individual submissions showed a decrease — a complete reversal of direction. The largest discrepancy was a single participant whose study data reported an increase of 32 mm³, while their individual submission showed a decrease of 48 mm³ — a reversal of approximately 80 mm³. The median change in soft plaque for these 8 participants was +20.6 mm³ (a 31% increase) in the original study data, compared to just +0.7 mm³ (about a 2% increase) from their individual submissions (Figure 2). The mean average is even more pronounced: the study data shows an average increase of +20.9 mm³ (42% from baseline), while the individual submissions show an average decrease of 5.1 mm³ (an 8% decline). In other words, the study data says plaque went up; the individual submissions say it went down (Figure 3). Direction of Change Across Platforms To put these individual submissions in broader context, Figure 4 compares the direction of soft plaque change across three analyses of these same scans. On the left is the original Cleerly study analysis — 99 participants after excluding one who had a procedure between scans. 98% showed an increase in soft plaque. Only 2 showed no change. Zero showed regression. In the middle are the 8 individual submissions, split right down the middle: 50% showing progression and 50% showing regression. On the right is the full Heartflow analysis across 95 participants. While 8 is a small sample size, the direction-of-change in these individual submissions is far closer to the Heartflow analysis than the original Cleerly analysis. It is worth emphasizing: 4 out of the 8 participants — fully half — received individual submission results showing less plaque in their second scan than their first. But after accounting for the single exclusion mentioned above, not one of the 99 participants in the original Cleerly study analysis showed plaque regression. We are not sure what happened with the original Cleerly analysis. We just know the other analyses are largely consistent with each other — and now, that includes these individual submissions to Cleerly as well. Next Steps We have already taken steps regarding last year's paper that contained the original Cleerly analysis. We are working with the journal on that now, and we expect news on this very soon. In the meantime, the preprint of our current paper with both Heartflow and QAngio results is available at the link below. Importantly, the two principal findings reported in the original paper have been reproduced in both the Heartflow and QAngio analyses: (1) baseline plaque strongly predicts future plaque progression, and (2) ApoB was not associated with plaque progression I want to once again thank Dr. Budoff and the Lundquist team for providing these scans to study participants who request them. If you are a participant in our study and interested in sending in your scans through your cardiologist, we now have a budget to help cover the cost of that submission. You can contact us at info@citizensciencefoundation.org for more details. Thank you again to everyone for your support. 🙏 cc @nicknorwitz @AdrianSotoMota
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Isn't this the same as when a meta analysis finds one paper is weaker than originally thought. It doesn't impact the overall power. I'm not sure why you are being so pedantic. But it is clear that the Cleerly Analysis that confuses the results is problematic in two ways: it contradicts the unblinded results, and it refuses to review the analysis in the face of questions. My first thought was 'why', cui bono. Surely an LLM needs more data and not an autocratic attitude.
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@NickEggleton He said he's referring to the published paper, not the preprint.
If they have determined the analysis was bad, and can't be corrected, they should retract it.
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@RealAlexJones Who will be the next republican candidate
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JD Vance’s performance in this new film has 100% secured his victory for president in 2028..
Alex Jones@RealAlexJones
HBO’s new trailer for their upcoming documentary on JD Vance is incredible. I am totally blown away right now..
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Don't you mean 'Next time check before you cash a bloke with a wig on.'
I never like him. Now I know why. What an ego to think he can tell us he paid a male sex worker to perform for him while pretending to be a woman and not be judged as 1) immoral and 2) a pervert. Where's his decency? Where's his shame?
Who goes on to the media and volunteers this information as acceptable? He's a nonce.
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Next time check before you pash on with a bloke with a wig on you 🤡
Clown Down Under 🤡@clowndownunder
Australian radio host Kyle Sandilands describes his night with a trans woman, saying, “if you’re with someone who believes they’re a woman, looks like a woman, says they’re a woman, then they’re a woman.”
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@drjoesDIYhealth It's the game of hiding the unemployable to hide unemployment in bureaucracy, diversity and dependency. Thats the Uniparty way. Socialism and Pseudosocilaism. Meanwhile Norway's Sovereign Wealth Fund...
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Australia also has a trillion dollars of debt.
Could be a connection
Don't you worry about that.🇦🇺@Sauronlordking
Japan has a population of 122 million and has 3.5 million public servants. Australia has a population of 27 million and 2.5 million public servants. Just saying.
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1) The point is reframing the CICO bs. 2) I never mentioned Keto. 3) The 'fat' stored in adipose tissue is triglycerides which require glycerol formed from glucose and is controlled by insulin not thermogenesis. 4) It was only meant to be constructive not critical the other 39 points are great. Props.
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@NickEggleton Nick people go keto all the time and still hit weight loss plateaus.
I’m not a carb fanatic but this is simply not correct.
No macro is easier to store as fat than fats themselves, though they can help with satiety and therefore lead to eating less.
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40 sentences that will teach you more about nutrition than a $400,000 medical degree.
40) Meat, eggs and animal organs are the most nutrient dense foods on the planet.
39) Bone broth is loaded in collagen and helps repair the gut so you can heal from the inside out.
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